Results 91 to 100 of about 367,425 (291)

Mechanisms and Pathophysiological Significance of Insulin Resistance in Offspring With Intrauterine Growth Restriction Mediated by Hepatic GR/miR‐1224 Programming

Advanced Science, EarlyView.
This work found that early‐stage insulin sensitization but late‐stage insulin resistance in prenatal caffeine exposure (PCE)‐ induced intrauterine growth restriction (IUGR) offspring may be related to the hepatic AGEs accumulation via intrauterine GR/miR‐1224 programming by glucocorticoids.
Yongguo Dai, Xiaoling Guo, Pengxia Yu, Dingmei Zhang, Hao Kou, Hui Wang   +5 more
wiley   +1 more source

Hyperglycemia in Pet African Pygmy Hedgehogs (Atelerix albiventris): Prevalence, Clinical Characteristics, and Prognostic Indicators of Severe Hyperglycemia

Animals
Hyperglycemia is known to negatively affect various animal species, but data on African pygmy hedgehogs remain limited. This study aimed to investigate the prevalence of hyperglycemia and evaluate the clinical characteristics and prognostic factors of ...
Do-Hyun Kwak, Myung-Chul Kim, Woo-Jin Song, Young-Min Yun   +3 more
doaj   +1 more source

Relationship between admitting nonfasting blood glucose and in-hospital mortality stratified by diabetes mellitus among acute coronary syndrome patients in Oman

Heart Views, 2011
Background and Objectives: Hyperglycemia in patients admitted for acute coronary syndrome (ACS) is associated with increased in-hospital mortality. We evaluated the relationship between admitting (nonfasting) blood glucose and in-hospital mortality in ...
Prashanth Panduranga, Kadhim Sulaiman, Jawad Al-Lawati, Ibrahim Al-Zakwani   +3 more
doaj   +1 more source

Pasireotide for the Medical Management of Feline Hypersomatotropism [PDF]

, 2015
BACKGROUND: Feline hypersomatotropism (HST) is a cause of diabetes mellitus in cats. Pasireotide is a novel multireceptor ligand somatostatin analog that improves biochemical control of humans with HST.
Abraham, Adams, Alt, Appleton, Bhayana, Bruns, Castillo, Church, Colao, Colao, Cuevas-Ramos, Fedele, Fernandez-Rodriguez, Fougner, Golor, Henry, Hofland, Juul, Katznelson, Kvols, Lamb, Lamberts, Maxwell, Meij, Miller, Murray, Myers, Niessen, Niessen, Niessen, Niessen, Petrus, Polska, Rand, Ray, Schmid, Schmid, Sheppard, Slingerland, Sohmiya, Starkey, Stolk, Taboada, Wajchenberg, Zatelli, Zou   +45 more
core   +2 more sources

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

Advanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Enhanced Integrin α4β1-Mediated Adhesion Contributes to a Mobilization Defect of Endothelial Progenitor Cells in Diabetes. [PDF]

, 2016
Diabetes is associated with a deficit of circulating endothelial progenitor cells (EPCs), which has been attributed to their defective mobilization from the bone marrow.
Abplanalp, Wesley T, Bhatnagar, Aruni, Cantor, Joseph M, Conklin, Daniel J, Ginsberg, Mark H, O'Toole, Timothy E, Wysoczynski, Marcin   +6 more
core   +2 more sources

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

Advanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu, Jintao Song, Mengjiao Guo, RuZe Ma, Mingyang Du, Zhe Xun, Xu Liu, RongXia Xu, Xiaochun Xie, Peilin Qi, Yujie Chen, Dan Shao, Chao Yang, Liang Wang, Xiaoyu Song, Difei Wang   +15 more
wiley   +1 more source

Nanozyme‐Engineered Probiotic Microneedle Patch for Chronic Diabetic Wound Therapy

Advanced Science, EarlyView.
This work introduces a robust living‐materials‐based strategy that integrates microbial therapy with catalytic nanotechnology for effective management of chronic infected wounds via alleviating reactive oxygen species (ROS), combating bacterial infection, relieving hypoxia, and exerting anti‐inflammatory effects.
Xueyang Wang, Shuhua Liu, Shisuo Jing, Siyu Zhang, Yinli Jin, Wen Zhang, Qiongfang Ruan, Wei Li   +7 more
wiley   +1 more source

New Technologies for Blood Glucose Management in Elderly Diabetics: An Interpretation of the Guidelines for the Management of Diabetes Mellitus in the Elderly in China (2024 Edition)

AGING MEDICINE, EarlyView.
This article reviews the latest advances in diabetes management technologies, and expound the technical principles, clinical benefits, and application dilemmas for elderly diabetes patients. ABSTRACT The burden of diabetes in the elderly is becoming increasingly severe due to the aging population.
Qingyun Cai, Peiyi Zhao, Xinda Chen, Shuyi Yu, Lixin Guo, Qi Pan   +5 more
wiley   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source