Results 71 to 80 of about 283,047 (289)

Evaluation of Mild Hyperglycemia During Early Pregnancy

open access: yes
Hyperglycemia and its association with adverse pregnancy outcomes have been comprehensively described in the literature. Moreover, researchers have just about reached a consensus regarding the diagnostics and intervention algorithms for hyperglycemia ...
Mustafa Aydemir   +2 more
core   +1 more source

Hierarchical Nanoplatform Integrating Oxidative–Acidic Microenvironment Remodeling and Bone Homeostasis Modulation for Diabetic Bone Defect Therapy

open access: yesAdvanced Science, EarlyView.
A hierarchical CM/LDH nanoplatform integrates ROS‐scavenging Ce‐MOF nanozymes with acid‐neutralizing CaAl‐LDH and is delivered within GelMA hydrogel to diabetic bone defects. By remodeling the oxidative‐acidic microenvironment, preserving mitochondrial homeostasis, and suppressing mtDNA–cGAS–STING inflammatory signaling, CM/LDH reduces proinflammatory ...
Xu Chen   +10 more
wiley   +1 more source

Development of a requirement for exogenous insulin treatment in dogs with hyperglycemia

open access: yesJournal of Veterinary Internal Medicine
Background It has been suggested that overt diabetes mellitus in dogs be defined based on a persistent fasting blood glucose concentration (BGC) >144 mg/dL.
Angielee DiNinni, Rebecka S. Hess
doaj   +1 more source

Prevalence of undiagnosed hyperglycemia and hypertension among middle-aged adults in Vietnam: A community-based study

open access: yesClinical Epidemiology and Global Health
Background: The information on prevalence of undiagnosed hyperglycemia, and hypertension among the adult in Vietnam is limited. The aim of this study was to identify the prevalence of undiagnosed intermediate hyperglycemia, hyperglycemia, and ...
Nguyen Thi Thi Tho   +10 more
doaj   +1 more source

The epidemiology of tuberculosis-associated hyperglycemia in individuals newly screened for type 2 diabetes mellitus: systematic review and meta-analysis

open access: yesBMC Infectious Diseases, 2020
Background There is scarce evidence that tuberculosis (TB) can cause diabetes in those not previously known to be diabetic. Whilst the World Health Organization (WHO) recommends screening for Diabetes Mellitus (DM) at the onset of TB treatment ...
Sonia Menon   +5 more
doaj   +1 more source

Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer’s disease

open access: yesCommunications Biology, 2021
To investigate the effects of chronic hyperglycemia on hippocampal network activity Wirt et al induced sustained hyperglycemia in rats and tested them in a spatial delayed alternation task while recording from the hippocampus and anterior cingulate ...
Ryan. A. Wirt   +6 more
doaj   +1 more source

Programmable Self‐Heating Microneedle Patch for on‐Demand Postprandial Glucose Management

open access: yesAdvanced Science, EarlyView.
A programmable self‐heating microneedle patch enables on‐demand, timed‐sequence insulin delivery via user‐triggered quadrant activation. Each activation generates localized heat that melts a phase‐change barrier, accelerating drug release. In diabetic rats, sequential quadrant activation counteracts four meal‐mimicking glucose spikes over 24 h without ...
Yang Zhao   +9 more
wiley   +1 more source

Complications of Acute and Chronic Hyperglycemia

open access: yes, 2017
Hyperglycemia is due to a dysregulation in the complex mechanisms implicated in glucose homeostasis. Chronic hyperglycemia, as measured by hemoglobin A1c (HbA1c), is a key risk factor for the development of microvascular and macrovascular complications ...
null null, M Loredana Marcovecchio
core   +3 more sources

Influence of Hyperglycemia on the Prognosis of Patients with Diffuse Large B-Cell Lymphoma

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2022
Weiling Zhou,1 Weijing Li,2 Cuiying He,2 Ruijuan Ma,2 Qian Gao,1 Yuan Wang,1 Lei Feng,1 Lihong Liu2 1Department of Endocrine and Metabolic Diseases, The Fourth Hospital of Hebei Medical University (Hebei Tumor Hospital), Shijiazhuang, People’s Republic ...
Zhou W   +7 more
doaj  

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

open access: yesAdvanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He   +7 more
wiley   +1 more source

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