Results 61 to 70 of about 255,764 (296)

Association of admission blood glucose and postoperation fast blood glucose with futile recanalization in patients with endovascular therapy

BMC Neurology
Background Futile recanalization (FR), defined as patients with long-term functional dependence despite successful recanalization, is common in patients with large-vessel stroke undergoing endovascular treatment (EVT). The present study aimed to identify
Dandan Chen, Yunqing Chen, Linghong Guo, Zubing Xu, Xian Liu, Xilin Xiong, Hudie Zhang, Yan Gong, Qiulong Yu, Chenying Zeng, Lanjiao Zhang, Qin Huang, Jinchong Zhang, Keji Zou, Xiaobing Li, Daojun Hong, Pu Fang, Jing Lin   +17 more
doaj   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Hyperglycemia

The Professional Medical Journal, 2015
Objectives: To investigate blood glucose regulaitng effects of CatharanthusRoseus (C.roseus) and Nigella sativa (N.sativa) in alloxan induced diabetic rats. Study Design:Experimental study. Place and Duration: Animal house Isra University Hyderabad. From Aprilto Novermber 2013.
Francesco Paneni, Francesco Cosentino
openaire   +3 more sources

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Erythropoietin ameliorates hyperglycemia in type 1-like diabetic rats [PDF]

, 2016
Ho-Shan Niu,1 Chin-Hong Chang,2,3 Chiang-Shan Niu,1 Juei-Tang Cheng,3,4 Kung-Shing Lee5–7 1Department of Nursing, Tzu Chi University of Science and Technology, Hualien City, Taiwan, Republic of China; 2Department of Neurosurgery, 3Department of ...
Niu CS, Lee KS, Niu HS, Chang CH, Cheng JT   +4 more
core  

Neonatal Hyperglycemia [PDF]

, 2010
Neonatal hyperglycemia is one of the most common metabolic abnormalities encountered in preterm and critically ill newborns. Although the definition varies, a blood glucose concentration greater than 125 mg/dL (6.9 mmol/L) or a plasma or serum glucose ...
Paul J. Rozance, William W. Hay
core   +1 more source

Detrimental Effect of Acute Hyperglycemia on the Outcomes of Large Ischemic Region Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Although endovascular therapy (EVT) is effective for large ischemic region strokes, the impact of hyperglycemia remains unclear. Methods and Results We analyzed data from the RESCUE‐Japan LIMIT (Recovery by Endovascular Salvage for Cerebral ...
Kanta Tanaka, Takeshi Yoshimoto, Junpei Koge, Hiroshi Yamagami, Hirotoshi Imamura, Nobuyuki Sakai, Kazutaka Uchida, Mikiya Beppu, Yuji Matsumaru, Yasushi Matsumoto, Kazumi Kimura, Reiichi Ishikura, Manabu Inoue, Fumihiro Sakakibara, Takeshi Morimoto, Shinichi Yoshimura, Kazunori Toyoda   +16 more
doaj   +1 more source

Postprandial hyperglycemia as an etiological factor in vascular failure

Cardiovascular Diabetology, 2009
Postprandial hyperglycemia is characterized by hyperglycemic spikes that induce endothelial dysfunction, inflammatory reactions and oxidative stress, which may lead to progression of atherosclerosis and occurrence of cardiovascular events.
Inoue Teruo, Node Koichi
doaj   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source