Results 41 to 50 of about 283,047 (289)

Management of Phosphatidylinositol-3-Kinase Inhibitor-Associated Hyperglycemia

open access: yesIntegrative Cancer Therapies, 2022
Phosphatidylinositol-3-kinase (PI3K) pathway hyperactivation has been associated with the development of cancer and treatment resistance. PI3K inhibitors are now used to treat hormone receptor-positive (HR+), human epidermal growth factor receptor-2 ...
Marcus D. Goncalves MD, PhD   +1 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Incidence, risk factors and complications of hyperglycemia in very low birth weight infants

open access: yesEgyptian Pediatric Association Gazette, 2017
Background: Prevalence of hyperglycemia in preterm infants varies widely between 20% and 88%. Hyperglycaemia in very low birth weight infants (VLBW) is associated with increased morbidity (necrotizing enterocolitis, late onset sepsis, intraventricular ...
Dina Mohammed Akmal   +3 more
doaj   +1 more source

Stress Hyperglycemia in Children and Adolescents as a Prognostic Indicator for the Development of Type 1 Diabetes Mellitus

open access: yesFrontiers in Pediatrics, 2021
Hyperglycemia is a common manifestation in the course of severe disease and is the result of acute metabolic and hormonal changes associated with various factors such as trauma, stress, surgery, or infection.
Theodoros Argyropoulos   +6 more
doaj   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk   +10 more
wiley   +1 more source

Hyperglycemia-induced Nonconvulsive Status Epilepticus (NCSE) and Cranial Magnetic Resonance Imaging Results: A Case Presentation

open access: yes, 2017
Epileptic seizure occur in up to 25% of cases of, non-ketotic hyperglycemia (NKH). These seizures are the first finding of diabetes mellitus in 50% of the patients.
Melek ÇOLAK ATMACA, Murat Mert ATMACA
core   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Glycemic Characteristics and Clinical Outcomes in Patients with COVID-19 Admitted to Referral Shahid Sayad Shirazi Hospital in Gorgan, North of Iran

open access: yesInterdisciplinary Perspectives on Infectious Diseases, 2023
Background. Diabetes mellitus (DM) is one of the most common chronic diseases, the main manifestation of which is hyperglycemia, and is accompanied by many complications.
Saba Kordrostami   +3 more
doaj   +1 more source

Impact of glycemia and insulin treatment in fatal outcome of severe fever with thrombocytopenia syndrome

open access: yesInternational Journal of Infectious Diseases, 2022
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease with a high fatality rate. How the glucose level might affect the clinical outcome remains obscure. Methods: A multicenter study was performed in 2 hospitals
Honghan Ge   +15 more
doaj   +1 more source

Postprandial hyperglycemia: a new frontier in diabetes management? [PDF]

open access: yes, 2018
Postprandial hyperglycemia is one of the earliest abnormalities of glucose homeostasis associated with type-2 diabetes and it is markedly exaggerated in diabetic patients with fasting hyperglycemia.
Massimo Rinaldi   +2 more
core   +1 more source

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