Results 171 to 180 of about 201,593 (197)

Schisantherin A: Remodeling Gut Microbiota to Activate the Gut–Immune–Neural–Adipose Axis for Thermogenesis

iNew Medicine, EarlyView.
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Hyperglycemia Modulates the Expression of MAPK13, TSP1, and CXCR2 During Wound Healing in Sprague Dawley Rats. [PDF]

Biology (Basel)
Tran T, Patel J, Ho V, Teshome B, Rai V.
europepmc   +1 more source

Mesenchymal Stem Cell‐Mediated Vascular Regeneration in Diabetic Foot Ulcers via the Notch Signaling Pathway

Journal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the experimental design and key findings of the study on the role of mesenchymal stem cells (MSCs) and Notch signaling in diabetic foot ulcer (DFU) healing. The study involved five groups of BALB/c mice: Control, Model, MSCs Treatment, MSCs + Notch Inhibition, and MSCs + Notch Activation.
Feifei Li, Li Xu, Xin Hou, Dengfeng Zhu, Jingming Ou, Zuwei Yang, Yuhong Gu   +6 more
wiley   +1 more source

Stress hyperglycemia ratio and physical frailty in HFpEF. [PDF]

Cardiovasc Diabetol
Mone P, Komici K, Guerra G, Dazzetti T, Kansakar U, Gennarelli G, Rainone A, Macina G, Di Mauro M, Iaccarino G, Testa G, Santulli G.   +11 more
europepmc   +1 more source

Wild‐Derived House Mice (Mus musculus) Are Able to Cope With a Constant Light Environment

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Exposure to altered nighttime lighting conditions has become common in today's modern world. Light at night disrupts circadian processes that govern feeding patterns, sleep/wake cycles, and metabolic homoeostasis, increasing the risk of developing pathologies associated with cardiometabolic disease. Yet, the underlying mechanism(s) responsible
Kevin Pham, KayLene Y. H. Yamada, Emma M. Rhodes, Agata. M. Rudolf, Wendy R. Hood   +4 more
wiley   +1 more source

From Pathophysiology to Treatment: Contemporary Approaches to CFRD in the Pediatric and Adolescent Population. [PDF]

Pediatr Diabetes
Vuralli D.
europepmc   +1 more source

Transforming healthcare with large language models: Current applications, challenges, and future directions—a literature review

Journal of Intelligent Medicine, EarlyView.
Abstract AI‐based large language models (LLMs) have gradually made their way into various fields, transforming industries and changing the way we solve problems. LLMs have great potential in healthcare, where they can share the burden of data management, retrieval, and decision‐making.
Muhammad Umar, Vanessa Ali, Laiba Shamim, Imshaal Musharaf, Rabia Hafsa, Muhammad Umar Ahsan, Osama Ahmad, Lamea Bint Sabhan, Muhammad Saeed, Somaiya Ahmed, Sana Iftikhar, Noor Ul Ain   +11 more
wiley   +1 more source

Diabetes: A Subspecialty of Medicine and a Matter of Public Health. [PDF]

Diabetes Metab Syndr Obes
Conway RB.
europepmc   +1 more source

Comparing perinatal outcomes in gestational and cystic‐fibrosis related diabetes

International Journal of Gynecology &Obstetrics, EarlyView.
Briana Clifton, Basra Osman, Katelyn M. Tessier, Kathleen S. Mahan, Amir Moheet, Sarah A. Wernimont   +5 more
wiley   +1 more source