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Glucose metabolism and hyperglycemia [PDF]
Islet dysfunction and peripheral insulin resistance are both present in type 2 diabetes and are both necessary for the development of hyperglycemia. In both type 1 and type 2 diabetes, large, prospective clinical studies have shown a strong relation between time-averaged mean values of glycemia, measured as glycated hemoglobin (HbA1c), and vascular ...
GIUGLIANO, Dario+2 more
openaire +5 more sources
Hyperglycemia induced by pasireotide in patients with Cushing’s disease or acromegaly [PDF]
PURPOSE: Cushing’s disease (CD) and acromegaly are characterized by excessive hormone secretion resulting in comorbidities such as impaired glucose metabolism, diabetes and hypertension.
Silverstein, Julie M
core +2 more sources
Acute Hyperglycemia Associated with Anti-Cancer Medication [PDF]
Hyperglycemia during chemotherapy occurs in approximately 10% to 30% of patients. Glucocorticoids and L-asparaginase are well known to cause acute hyperglycemia during chemotherapy.
Yul Hwangbo, Eun Kyung Lee
doaj +1 more source
The Influence of Hyperactivity of the Hypothalamic-pituitary-adrenal Axis and Hyperglycemia on the 5-HT2A Receptor-mediated Wet-dog Shake Responses in Rats [PDF]
Hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis induces hyperglycemia and serotonin (5-HT)2A receptor supersensitivity. In the present study, to investigate the effect of hyperglycemia on the function of 5-HT2A receptors, we compared the 5-
Amano, Manabu+7 more
core +1 more source
Insular cortex hypoperfusion and acute phase blood glucose after stroke: a CT perfusion study [PDF]
<p><b>Background and Purpose:</b> Insular cortex ischemia is proposed to mediate a sympathetic stimulus that leads to acute hyperglycemia after stroke.</p> <p><b>Methods:</b> We retrospectively analyzed ...
McCormick, M., Moreton, F.C., Muir, K.W.
core +1 more source
Hyperglycemia triggers HIPK2 protein degradation [PDF]
Homeodomain interacting protein kinase-2 (HIPK2) is an evolutionary conserved kinase that modulates several key molecular pathways to restrain tumor growth and induce p53-depending apoptotic cell-death in response to anticancer therapies. HIPK2 silencing
Baldari, Silvia+6 more
core +2 more sources
Background: Hyperglycemia is implicated as deleterious in acute stroke, although the impact may vary by stroke subtype. We sought to determine the frequency of admission hyperglycemia (subcategorized as diabetes related or reactive) and explore the ...
Osigwe Paul Agabi+4 more
doaj +1 more source
Hyperglycemia is the elevation of blood glucose concentrations above the normal range. Prolonged uncontrolled hyperglycemia is associated with serious life-threatening complications. Hyperglycemia arises from an imbalance between glucose production and glucose uptake and utilization by peripheral tissues.
Lucy A. Ochola, Eric M. Guantai
openaire +4 more sources
Sugar and Stops in Drivers with Insulin-Dependent Type 1 Diabetes [PDF]
Diabetes is a major public health challenge worldwide. Abnormal physiology in diabetes, particularly hypoglycemia, can cause driver impairments that affect safe driving. While diabetes driver safety has been previously researched, few studies link real-time physiologic changes in drivers with diabetes to objective real-world driver safety, particularly
arxiv +1 more source
Association of preoperative blood glucose level with delirium after non-cardiac surgery in diabetic patients [PDF]
Background Hyperglycemia has shown a negative association with cognitive dysfunction. We analyzed patients with high preoperative blood glucose level and hemoglobin A1c (HbA1c) level to determine the prevalence of postoperative delirium.
Soo Jung Park+4 more
doaj +1 more source