BMC Pediatrics, 2010 Background Hyperglycemia in premature infants is associated with increased morbidity and mortality, but data on long-term outcome are limited. We investigated the effects of neonatal hyperglycemia (blood glucose ≥ 10 mmol/l, treated with insulin for ≥ 12
van Zwieten Paul HT +3 more
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TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice [PDF]
, 2017 Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure. We previously reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure overload-induced maladaptive ...
Birnbaumer, Lutz +10 more
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Correlation of hyperglycemia with mortality after acute ischemic stroke
Therapeutic Advances in Neurological Disorders, 2018 Background: Hyperglycemia has been considered a predictor of stroke outcomes. In this article we study the correlation between blood glucose levels within the first 24 h after stroke onset and patients’ outcomes in mortality and hemorrhagic ...
Donghua Mi +5 more
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Management of Phosphatidylinositol-3-Kinase Inhibitor-Associated Hyperglycemia
Integrative Cancer Therapies, 2022 Phosphatidylinositol-3-kinase (PI3K) pathway hyperactivation has been associated with the development of cancer and treatment resistance. PI3K inhibitors are now used to treat hormone receptor-positive (HR+), human epidermal growth factor receptor-2 ...
Marcus D. Goncalves MD, PhD +1 more
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Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats [PDF]
, 2013 Background: Metabolic syndrome (coexisting visceral obesity, dyslipidemia, hyperglycemia, and hypertension) is a prominent risk factor for cardiovascular morbidity and mortality, however, its effect on cardiac gene expression pattern is unclear ...
Csonka, Csaba +10 more
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Acta Medica Indonesiana, 2016 Aim: to determine the difference in serum matrix metalloproteinase-9 (MMP-9) levels among acute coronary syndrome patients with and without hyperglycemia.
Budi Y Setianto +2 more
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The Role of Intensive Insulin Therapy on Superoxide Dismutase (Sod), Tumor Necrosis Factor-? (Tnf-?), and Interleukin-6 (Il-6) on Hyperglycemia in Critically Ill Patients [PDF]
, 2009 Hyperglycemia and insulin resistance are common in critically ill patientsin the ICU, although they have not previously had diabetes. It has been reportedthat pronounced hyperglycemia may lead to complications in such patients, andcause the reactive ...
Bagianto, H. (Hari) +3 more
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Frontiers in Pediatrics, 2021 Hyperglycemia is a common manifestation in the course of severe disease and is the result of acute metabolic and hormonal changes associated with various factors such as trauma, stress, surgery, or infection.
Theodoros Argyropoulos +6 more
doaj +1 more source
Combined therapy with GABA and proinsulin/alum acts synergistically to restore long-term normoglycemia by modulating T-cell autoimmunity and promoting β-cell replication in newly diabetic NOD mice. [PDF]
, 2014 Antigen-based therapies (ABTs) fail to restore normoglycemia in newly diabetic NOD mice, perhaps because too few β-cells remain by the time that ABT-induced regulatory responses arise and spread.
Chen, Zheying +4 more
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Incidence, risk factors and complications of hyperglycemia in very low birth weight infants
Egyptian Pediatric Association Gazette, 2017 Background: Prevalence of hyperglycemia in preterm infants varies widely between 20% and 88%. Hyperglycaemia in very low birth weight infants (VLBW) is associated with increased morbidity (necrotizing enterocolitis, late onset sepsis, intraventricular ...
Dina Mohammed Akmal +3 more
doaj +1 more source