Results 21 to 30 of about 206,476 (232)

Glycemic Characteristics and Clinical Outcomes in Patients with COVID-19 Admitted to Referral Shahid Sayad Shirazi Hospital in Gorgan, North of Iran

Interdisciplinary Perspectives on Infectious Diseases, 2023
Background. Diabetes mellitus (DM) is one of the most common chronic diseases, the main manifestation of which is hyperglycemia, and is accompanied by many complications.
Saba Kordrostami, Maryam Zahedi, Abdolhalim Rajabi, Shahab Eskandari-Nejad   +3 more
doaj   +1 more source

Impact of glycemia and insulin treatment in fatal outcome of severe fever with thrombocytopenia syndrome

International Journal of Infectious Diseases, 2022
Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease with a high fatality rate. How the glucose level might affect the clinical outcome remains obscure. Methods: A multicenter study was performed in 2 hospitals
Honghan Ge, Jing Zhao, Shuai Zhang, Yanli Xu, Yuanni Liu, Xuefang Peng, Gang Wang, Xiaoyi Gong, Ligang Zhang, Shuang Li, Hao Li, Xiao-Ai Zhang, Ning Cui, Chun Yuan, Ling Lin, Wei Liu   +15 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Hyperglycemia

The Professional Medical Journal, 2015
Objectives: To investigate blood glucose regulaitng effects of CatharanthusRoseus (C.roseus) and Nigella sativa (N.sativa) in alloxan induced diabetic rats. Study Design:Experimental study. Place and Duration: Animal house Isra University Hyderabad. From Aprilto Novermber 2013.
Francesco Paneni, Francesco Cosentino
openaire   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Persistent Hyperglycemia Is Associated With Increased Mortality After Intracerebral Hemorrhage

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundHyperglycemia may be associated with worse outcome after intracerebral hemorrhage (ICH). We assessed the association of early glycemic trajectory on ICH mortality and edema growth.
Teddy Y. Wu, Jukka Putaala, Gagan Sharma, Daniel Strbian, Turgut Tatlisumak, Stephen M. Davis, Atte Meretoja   +6 more
doaj   +1 more source

Intermediate Hyperglycemia Increases the Risk of All-Cause Mortality in Premature Coronary Artery Disease Patients Undergoing Percutaneous Coronary Intervention

Reviews in Cardiovascular Medicine, 2023
Background: Hyperglycemia has been associated with an adverse prognosis in patients with premature coronary artery disease (CAD). However, whether the intermediate hyperglycemia status affects the risk of mortality in premature CAD patients treated with ...
Ziyou Zhou, Linfang Qiao, Yihang Ling, Yibo He, Tian Chang, Hongyu Lu, Sijia Yu, Jin Liu, Wei Guo, Shiqun Chen, Yong Liu, Jiyan Chen   +11 more
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Incidence and risk factors of intraoperative hyperglycemia in non-diabetic patients: a prospective observational study

BMC Anesthesiology, 2022
Background Intraoperative hyperglycemia has been associated with multiple postoperative complications such as surgical site infection, myocardial infarction, stroke, and death. These complications are not confined to only diabetic patients.
Varunya Sermkasemsin, Mali Rungreungvanich, Worapot Apinyachon, Inthuon Sangasilpa, Wanlee Srichot, Chawika Pisitsak   +5 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source