Hypergravity Attenuates Reactivity in Primary Murine Astrocytes [PDF]
Neuronal activity is the key modulator of nearly every aspect of behavior, affecting cognition, learning, and memory as well as motion. Hence, disturbances of the transmission of synaptic signals are the main cause of many neurological disorders. Lesions
Yannick Lichterfeld +8 more
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Insect exoskeletons react to hypergravity [PDF]
A typical feature of biological materials is their ability to adapt to mechanical load. However, it is not known whether the cuticle exoskeleton, one of the most common biological structures, also shares this trait. Here, we show direct experimental evidence that prolonged exposure to hypergravity conditions affects the morphology and biomechanics of ...
Karen Stamm, Jan-Henning Dirks
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Simulated Hypergravity Activates Hemostasis in Healthy Volunteers [PDF]
Background Hypergravity may promote human hemostasis thereby increasing thrombotic risk. Future touristic suborbital spaceflight will expose older individuals with chronic medical conditions, who are at much higher thromboembolic risk compared with ...
Ulrich Limper +9 more
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Measuring Intracellular Viscosity in Conditions of Hypergravity [PDF]
Gravity-sensitive cellular responses are regularly observed in both specialized and nonspecialized cells. One potential mechanism for this sensitivity is a changing viscosity of the intracellular organelles. Here, we report a novel, to our knowledge, viscosity-sensitive molecular rotor based on mesosubstituted boron-dipyrrin used to investigate the ...
Woodcock, EM +7 more
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Hypergravity Conditioning on Ileal Movements in Rats [PDF]
Stress is a common trigger for various physiological disturbances, including feeding disorders. One of the possible mechanisms for feeding disorders may be linked to changes in intestinal movement caused by stress. Therefore, here we investigated in vitro stress-induced changes in ileal movement.Rats (female Wistar, SPF) were divided into Control (1 G)
Mari, Kimoto +2 more
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Application of hypergravity in Eucalyptus and Corymbia seeds [PDF]
: The aim of this study was to evaluate the growth responses of various Eucalyptus and Corymbia species subjected to different intensities of simulated hypergravity relative to the control. A centrifuge was used to simulate hypergravity. It was developed
Andrei Caíque Pires Nunes +6 more
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Hippocampal gene expression is modulated by hypergravity [PDF]
AbstractWe used the cDNA microarray technique to monitor simultaneously possible changes induced by hypergravity in the expression level of thousands of hippocampal genes. We tested the mRNA level of about 5000 genes in the hippocampus of mice subjected to 1.09 g (1g) or to 1.85 g (2g) for five repeated 1‐h daily rotations in a centrifuge (g = 9.81 m ...
A. Del Signore +7 more
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Hypergravity as a Tool for Cell Stimulation: : Implications in Biomedicine [PDF]
Gravity deeply influences numerous biological events in living organisms. Variations in gravity values induce adaptive reactions that have been shown to play important roles, for instance in cell survival, growth, and spatial organization. In this paper,
Giada Graziana Genchi +9 more
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An instrumented centrifuge for studying mouse locomotion and behaviour under hypergravity [PDF]
Gravity may influence multiple aspects of legged locomotion, from the periods of limbs moving as pendulums to the muscle forces required to support the body.
Benjamin J. H. Smith, James R. Usherwood
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Barium titanate nanoparticles and hypergravity stimulation improve differentiation of mesenchymal stem cells into osteoblasts [PDF]
Antonella Rocca,1,2 Attilio Marino,1,2 Veronica Rocca,3 Stefania Moscato,4 Giuseppe de Vito,5,6 Vincenzo Piazza,5 Barbara Mazzolai,1 Virgilio Mattoli,1 Thu Jennifer Ngo-Anh,7 Gianni Ciofani1 1Istituto Italiano di Tecnologia, Center for Micro-BioRobotics
Rocca A +9 more
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