Results 11 to 20 of about 2,697 (226)

Effects of Hypergravity on Osteopontin Expression in Osteoblasts. [PDF]

PLoS ONE, 2015
Mechanical stimuli play crucial roles in bone remodeling and resorption. Osteopontin (OPN), a marker for osteoblasts, is important in cell communication and matrix mineralization, and is known to function during mechanotransduction.
Shuai Zhou, Yan Zu, Zhenglong Sun, Fengyuan Zhuang, Chun Yang   +4 more
doaj   +5 more sources

Modulation of vestibular function and receptor expression by experimental hypergravity in a rat model [PDF]

Scientific Reports
Motion sickness develops because of a mismatch or conflict between the information gathered from the visual input, somatosensory input, and the vestibular system. Altered gravity can cause motion sickness while traveling in space. In this study, we aimed
Jin Sil Choi, Ji Eun Hong, Yoon Kun Jung, Kyu-Sung Kim, Hyun Ji Kim   +4 more
doaj   +2 more sources

Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes [PDF]

Cells, 2019
Functional studies of human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (hCMs) under different gravity conditions contribute to aerospace medical research.
Aviseka Acharya, Sonja Brungs, Yannick Lichterfeld, Jürgen Hescheler, Ruth Hemmersbach, Helene Boeuf, Agapios Sachinidis   +6 more
doaj   +2 more sources

Effects of altered gravity on adrenergic-mediated cAMP signalling in intact cells [PDF]

npj Microgravity
Spaceflight-induced cardiac atrophy and rhythm disorders are linked to dysregulation of the adrenergic-cAMP-PKA pathway. Gravity-dependent alterations in adrenergic signaling, particularly cAMP dynamics, remain poorly understood.
Marc Bathe-Peters, Iqra Sohail, Alexei Sirbu, Katharina Schneider, Tommaso Patriarchi, Anantha Anilkumar, Yannick Lichterfeld, Christian Liemersdorf, Primal de Lanerolle, Paolo Annibale   +9 more
doaj   +2 more sources

Hypergravity is more challenging than microgravity for the human sensorimotor system [PDF]

npj Microgravity
The importance of gravity for human motor control is well established, but it remains unclear how the central nervous system accounts for gravitational changes to perform complex motor skills.
Loïc Chomienne, Patrick Sainton, Fabrice R. Sarlegna, Lionel Bringoux   +3 more
doaj   +2 more sources

Hypergravity Attenuates Reactivity in Primary Murine Astrocytes [PDF]

Biomedicines, 2022
Neuronal activity is the key modulator of nearly every aspect of behavior, affecting cognition, learning, and memory as well as motion. Hence, disturbances of the transmission of synaptic signals are the main cause of many neurological disorders. Lesions
Yannick Lichterfeld, Laura Kalinski, Sarah Schunk, Theresa Schmakeit, Sebastian Feles, Timo Frett, Harald Herrmann, Ruth Hemmersbach, Christian Liemersdorf   +8 more
doaj   +5 more sources

Tunable flexible capacitive sensor for dynamic pressure monitoring [PDF]

Microsystems & Nanoengineering
Flexible capacitive pressure sensors have gained widespread application in health monitoring, robotics, and structural diagnostics. However, conventional designs that rely on flat or micropatterned dielectric layers typically offer high sensitivity only ...
Haoran Fu, Zhehui Zhao, Jianqun Jiang, Yunmin Chen, Haoyu Zhang, Haoran Li, Guanwen Liang   +6 more
doaj   +2 more sources

Hypergravity Enhances Stretch Sensitivity in Rat Cardiomyocytes via Increased Expression and Activity of Stretch-Activated Channels. [PDF]

Int J Mol Sci
Kamkin AG, Zolotarev VI, Kamkina O, Mitrokhin VM, Kazansky VE, Bilichenko A, Rodina AS, Zolotareva AD, Mladenov M.   +8 more
europepmc   +3 more sources

Numerical simulation of the effect of hypergravity on the dendritic growth characteristics of aluminum alloys [PDF]

Heliyon
The cellular automata-lattice Boltzmann method is used to simulate the dendritic growth process of aluminum alloys under the action of hypergravity by performing coupling heat and mass transfer, solidification and flow.
Yanying Zhang, Ruifeng Dou, Junsheng Wang, Xunliang Liu, Zhi Wen   +4 more
doaj   +2 more sources

A Prebiotic Diet Containing Galactooligosaccharides and Polydextrose Attenuates Hypergravity-Induced Disruptions to the Microbiome in Female Mice. [PDF]

Nutrients
Thompson RS, Hopkins S, Kelley T, Wilson CG, Pecaut MJ, Fleshner M.   +5 more
europepmc   +3 more sources