From central to pulmonary capillary blood volume: Evidence for a non-linear relationship with pulmonary diffusing capacity. [PDF]
J PhysiolThe Journal of Physiology, Volume 604, Issue 18, Page 7523-7524, 15 September 2026.
Berg RMG.
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Simulated Hypergravity Activates Hemostasis in Healthy Volunteers
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background Hypergravity may promote human hemostasis thereby increasing thrombotic risk. Future touristic suborbital spaceflight will expose older individuals with chronic medical conditions, who are at much higher thromboembolic risk compared with ...
Ulrich Limper +9 more
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Effects of gravity changes on gene expression of BDNF and serotonin receptors in the mouse brain. [PDF]
PLoS ONE, 2017 Spaceflight entails various stressful environmental factors including microgravity. The effects of gravity changes have been studied extensively on skeletal, muscular, cardiovascular, immune and vestibular systems, but those on the nervous system are not
Chihiro Ishikawa +9 more
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Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment. [PDF]
Adv Healthc MaterChitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Adebowale M +4 more
europepmc +2 more sources
Hypergravity down-regulates c-fos gene expression via ROCK/Rho-GTP and the PI3K signaling pathway in murine ATDC5 chondroprogenitor cells. [PDF]
PLoS ONE, 2017 Chondrocytes are known to be physiologically loaded with diverse physical factors such as compressive stress, shear stress and hydrostatic pressure. Although the effects of those mechanical stimuli onto various cell models have been widely studied, those
Jeonghyun Kim +4 more
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From microgravity to hypergravity: Perspectives on circulatory adaptation through multiscale modelling. [PDF]
J PhysiolThe Journal of Physiology, Volume 604, Issue 13, Page 5076-5077, 1 July 2026.
Collia D, Zovatto L, Pedrizzetti G.
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Life, 2022 Terrestrial plants respond to and resist gravitational force. The response is termed “gravity resistance”, and centrifugal hypergravity conditions are efficient for investigating its nature and mechanism.
Takayuki Hattori +3 more
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The effect of different gravity fields on mass transfer in the rat bone lacunar-canalicular system
Medicine in Novel Technology and Devices, 2023 The bone lacunar-canalicular system (LCS) is an important microscopic infrastructure for signaling and solute transport in bone tissue, which guarantees normal physiological processes of the tissue, but the mass transfer laws in the LCS under different ...
Hao Wang +7 more
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Application of hypergravity in Eucalyptus and Corymbia seeds
Ciência Rural, 2018 : The aim of this study was to evaluate the growth responses of various Eucalyptus and Corymbia species subjected to different intensities of simulated hypergravity relative to the control. A centrifuge was used to simulate hypergravity. It was developed
Andrei Caíque Pires Nunes +6 more
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Hypergravity-induced changes in actin response of breast cancer cells to natural killer cells
Scientific Reports, 2021 Although immunotherapy holds promising cytotoxic activity against lymphoma or leukemia, the immunosuppressive mechanisms of solid tumors remain challenging.
Minseon Lee, Dongjoo Kim, Soonjo Kwon
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