Hypergravity down-regulates c-fos gene expression via ROCK/Rho-GTP and the PI3K signaling pathway in murine ATDC5 chondroprogenitor cells. [PDF]
PLoS ONE, 2017 Chondrocytes are known to be physiologically loaded with diverse physical factors such as compressive stress, shear stress and hydrostatic pressure. Although the effects of those mechanical stimuli onto various cell models have been widely studied, those
Jeonghyun Kim +4 more
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The effect of different gravity fields on mass transfer in the rat bone lacunar-canalicular system
Medicine in Novel Technology and Devices, 2023 The bone lacunar-canalicular system (LCS) is an important microscopic infrastructure for signaling and solute transport in bone tissue, which guarantees normal physiological processes of the tissue, but the mass transfer laws in the LCS under different ...
Hao Wang +7 more
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The Impact of Microgravity and Hypergravity on Endothelial Cells [PDF]
BioMed Research International, 2015 The endothelial cells (ECs), which line the inner surface of vessels, play a fundamental role in maintaining vascular integrity and tissue homeostasis, since they regulate local blood flow and other physiological processes. ECs are highly sensitive to mechanical stress, including hypergravity and microgravity.
Jeanette A. M. Maier +3 more
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Adrenalectomy abolishes hypergravity-induced gastric acid hyposecretion [PDF]
, 2017 Jet fighter pilots experience high gravitational acceleration forces in the cephalocaudal direction (+Gz), causing severe stress. Stress affects different physiological functions of the gastrointestinal tract.
김현수
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Hypergravity-induced changes in actin response of breast cancer cells to natural killer cells
Scientific Reports, 2021 Although immunotherapy holds promising cytotoxic activity against lymphoma or leukemia, the immunosuppressive mechanisms of solid tumors remain challenging.
Minseon Lee, Dongjoo Kim, Soonjo Kwon
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Effect of 8 days of a hypergravity condition on the sprinting speed and lower-body power of elite rugby players [PDF]
, 2015 -Sprinting speed and lower-body power are considered to be key physical abilities for rugby players. A method of improving the lower-body power of athletes is simulated hypergravity.
Newton, Robert U. +3 more
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data_in_EFA;3D_plot_example_fig7a;2D_plot_example_fig12 from Equivalent in-plane elastic moduli of honeycomb materials under hypergravity conditions [PDF]
, 2023 Honeycomb materials frequently encounter hypergravity conditions in both aerospace and biological contexts during phases such as launch, reentry or under centrifugal motion. The significant body force engendered by hypergravity induces alterations in the
Lei Wang (6656) +2 more
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Impacts of the Spaceflight to the Immune System
Hanggong uju uihakoeji, 2021 Changes the gravity has a significant affect on the immune system. Astronauts experience the gravity changing during spaceflight, especially when launching and landing they experience hypergravity, and during spaceflight they feel microgravity.
Doston Sultonov, Young Hyo Kim
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Case Report: No Evidence of Intracranial Fluid Shifts in an Astronaut Following an Aborted Launch
Frontiers in Neurology, 2021 Spaceflight induces lasting enlargement of the brain's ventricles as well as intracranial fluid shifts. These intracranial fluid shifts have been attributed to prolonged microgravity exposure, however, the potential effects of hypergravity exposure ...
Heather R. McGregor +8 more
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