Results 51 to 60 of about 2,697 (226)

The importance of gravity vector on adult mammalian organisms: Effects of hypergravity on mouse testis.

PLoS ONE, 2023
In the age of space exploration, the effect of hypergravity on human physiology is a relatively neglected topic. However, astronauts have several experiences of hypergravity during their missions. The main disturbance of altered gravity can be imputed to
Valentina Bonetto, Valeria Magnelli, Maurizio Sabbatini, Flavia Caprì, Jack J W A van Loon, Sara Tavella, Maria Angela Masini   +6 more
doaj   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

50% body weight loading reduces stature increases and lumbar disc expansion from 4 h hyper‐buoyancy floatation versus 15 min sitting upright

Experimental Physiology, EarlyView.
Abstract Microgravity is associated with stature increases, back pain and post‐flight intervertebral disc (IVD) herniation. This study aims to determine whether 30 s seated 50% body weight (BW) axial loading is comparable to 15 min sitting upright in 1 g upon changes in stature, anterior lumbar IVD height (via ultrasound), passive vertebral stiffness ...
David Marcos‐Lorenzo, Christina Lysandrou, Laura Sudres, Alfonso Gil‐Martinez, Jaap Swanenburg, James Edward Clark, David Andrew Green   +6 more
wiley   +1 more source

An experimentally informed computational model of neurovestibular adaptation to altered gravity

Experimental Physiology, EarlyView.
Abstract Transitions to altered gravity environments result in acute sensorimotor impairment for astronauts, leading to serious mission and safety risks in the crucial first moments in a new setting. Our understanding of the time course and severity of impairment in the early stages of adaptation remains limited and confounded by unmonitored head ...
Victoria G. Kravets, Torin K. Clark
wiley   +1 more source

Effect of hypergravity on the biomechanics of the musculoskeletal system in human lumbar spine: a numerical study

Frontiers in Bioengineering and Biotechnology
The aim of this study was to investigate the effects of hypergravity on the biomechanics of the human lumbar spinal musculoskeletal system. We quantitatively analyzed the biomechanics of the intervertebral disc (IVD), lumbar spinal muscles, and ligament ...
Bing Qin, Lu Zhou, Xiaoyu Zhang, Yuheng Liu, Zhiyu Qian, Qiaoqiao Zhu   +5 more
doaj   +1 more source

Hypergravity as a Tool for Cell Stimulation: : Implications in Biomedicine

Frontiers in Astronomy and Space Sciences, 2016
Gravity deeply influences numerous biological events in living organisms. Variations in gravity values induce adaptive reactions that have been shown to play important roles, for instance in cell survival, growth, and spatial organization. In this paper,
Giada Graziana Genchi, Antonella Rocca, Antonella Rocca, Attilio Marino, Attilio Marino, Agostina Grillone, Agostina Grillone, Virgilio Mattoli, Gianni Ciofani, Gianni Ciofani   +9 more
doaj   +1 more source

Hypergravity Increases Blood–Brain Barrier Permeability to Fluorescent Dextran and Antisense Oligonucleotide in Mice

Cells, 2023
The earliest effect of spaceflight is an alteration in vestibular function due to microgravity. Hypergravity exposure induced by centrifugation is also able to provoke motion sickness.
David Dubayle, Arnaud Vanden-Bossche, Tom Peixoto, Jean-Luc Morel   +3 more
doaj   +1 more source

Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans

Experimental Physiology, EarlyView.
Abstract Hyperthermia can cause intestinal injury, facilitating endotoxin translocation and an inflammatory response that has been associated with heat illness. However, the potential occurrence of these responses has been incompletely reported during passive hyperthermia, and the independent effect of hyperthermia is equivocal.
Oliver R. Gibson, Orlando Laitano, Kazuhito Watanabe, José González‐Alonso   +3 more
wiley   +1 more source

The Impact of Altered Gravity and Vibration on Endothelial Cells During a Parabolic Flight

Cellular Physiology and Biochemistry, 2013
Background: Endothelial cells (EC) cultured under altered gravity conditions show a cytoskeletal disorganization and differential gene expression (short-term effects), as well as apoptosis in adherently growing EC or formation of tubular 3D structures ...
Markus Wehland, Xiao Ma, Markus Braun, Jens Hauslage, Ruth Hemmersbach, Johann Bauer, Jirka Grosse, Manfred Infanger, Daniela Grimm   +8 more
doaj   +1 more source

MCA1 and MCA2 Are Involved in the Response to Hypergravity in Arabidopsis Hypocotyls

Plants, 2020
Plants respond to and resist gravitational acceleration, but the mechanism of signal perception in the response is unknown. We studied the role of MCA (mid1-complementing activity) proteins in gravity perception by analyzing the expression of the MCA1 ...
Takayuki Hattori, Yasuhiro Otomi, Yohei Nakajima, Kouichi Soga, Kazuyuki Wakabayashi, Hidetoshi Iida, Takayuki Hoson   +6 more
doaj   +1 more source