Results 71 to 80 of about 2,586 (213)

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

Theoretical model of interstitial diffusion in solid solution under hypergravity conditions

AIP Advances
Diffusion of atoms and molecules is usually driven by concentration gradients, with the influence of gravitational energy being negligible. However, for alloying components operating at exceptional rotational speeds, such as engine blades, the resulting ...
Changyou Li, He Zhang, Haifei Zhan, Chaofeng Lü   +3 more
doaj   +1 more source

Stability Studies of UV Laser Irradiated Promethazine and Thioridazine after Exposure to Hypergravity Conditions

Molecules, 2022
Pharmaceuticals carried into space are subjected to different gravitational conditions. Hypergravity is encountered in the first stage, during spacecraft launching.
Ágota Simon, Tatiana Tozar, Adriana Smarandache, Mihai Boni, Alexandru Stoicu, Alan Dowson, Jack J. W. A. van Loon, Mihail Lucian Pascu   +7 more
doaj   +1 more source

Hyper‐buoyancy flotation increases cervical disc height and reduces vertebral stiffness, with only partial reversal after acute 1 g axial loading

Experimental Physiology, EarlyView.
Abstract Exposure to microgravity is associated with stature increases, moderate‐to‐severe back/neck pain and elevated lumbar and cervical intervertebral disc (IVD) herniation risk post‐flight. Whilst lumbar pathophysiology has been investigated, little attention has been placed on the cervical spine.
D. Marcos‐Lorenzo, P. Hernández Bernal, R. Fernández Corujo, A. Gil Martínez, J. Swanenburg, D. A. Green   +5 more
wiley   +1 more source

The Hormetic Effects of Hypergravity on Longevity and Aging [PDF]

Dose-Response, 2006
This paper reviews the literature on the effects of hypergravity (HG, gravity levels higher than 1g, the terrestrial gravity) on longevity and aging. The different studies showed that life-long exposures to high gravity levels decreased longevity and accelerated the age-related decline observed on some physiological and behavioral variables.
openaire   +3 more sources

Stability of Antimicrobial Drug Molecules in Different Gravitational and Radiation Conditions in View of Applications during Outer Space Missions

Molecules, 2021
The evolution of different antimicrobial drugs in terrestrial, microgravity and hypergravity conditions is presented within this review, in connection with their implementation during human space exploration.
Ágota Simon, Adriana Smarandache, Vicentiu Iancu, Mihail Lucian Pascu   +3 more
doaj   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source

Bubble Formation and Behaviour Under Hypergravity Conditions [PDF]

, 2010
Bubble formation and behaviour have been studied over decades, but the complex two-phase flow phenomena involved are still not fully understood. In view of the importance of two-phase flow processes in a broad range of industrial applications, such as ...
Christina Giannopapa, Balazs Toth, Anna Eiden, Alan Dowson   +3 more
core   +1 more source

Pharmacological Stimulation of Type 5 Adenylyl Cyclase Stabilizes Heart Rate Under Both Microgravity and Hypergravity Induced by Parabolic Flight

Journal of Pharmacological Sciences, 2012
We previously demonstrated that type 5 adenylyl cyclase (AC5) functions in autonomic regulation in the heart. Based on that work, we hypothesized that pharmacological modulation of AC5 activity could regulate the autonomic control of the heart rate under
Yunzhe Bai, Takashi Tsunematsu, Qibin Jiao, Yoshiki Ohnuki, Yasumasa Mototani, Kouichi Shiozawa, Meihua Jin, Wenqian Cai, Hui-Ling Jin, Takayuki Fujita, Yasuhiro Ichikawa, Kenji Suita, Reiko Kurotani, Utako Yokoyama, Motohiko Sato, Kousaku Iwatsubo, Yoshihiro Ishikawa, Satoshi Okumura   +17 more
doaj   +1 more source

Accuracy of next‐generation wireless skin temperature sensors during exercise–heat stress

Experimental Physiology, Volume 111, Issue 8, Page 3463-3479, 1 August 2026.
Abstract Skin temperature is fundamental in characterising human thermoregulatory responses. Wired probes, although accurate, restrict movement and are impractical outside laboratory settings. The iButton (DS1922L; Maxim Integrated, USA) is a widely used wireless alternative but does not meet the precision recommended by ISO 9886 and permits only ...
Aaron J. E. Bach, Norman R. Morris, Surendran Sabapathy, David N. Borg, Isabella Ennever, Pramod Sharma, Fergus K. O'Connor   +6 more
wiley   +1 more source