Results 61 to 70 of about 2,697 (226)

The Study of Hypergravity and Flight Stress on Different Cell Lines Function in Sounding Rocket [PDF]

فصلنامه علوم و فناوری فضایی, 2014
Stress environment of space flights including hypergravity and microgravity effect cell functions and processes. We studied effect of hypergravity and flight stress on function, death, growth and cellular damage of five cell lines including human ...
Z. Hajebrahimi, L. Alidoust, M. Arabian, E. Alavi, M. Ebrahimi, M. Bahrami   +5 more
doaj  

Stability Studies of UV Laser Irradiated Promethazine and Thioridazine after Exposure to Hypergravity Conditions

Molecules, 2022
Pharmaceuticals carried into space are subjected to different gravitational conditions. Hypergravity is encountered in the first stage, during spacecraft launching.
Ágota Simon, Tatiana Tozar, Adriana Smarandache, Mihai Boni, Alexandru Stoicu, Alan Dowson, Jack J. W. A. van Loon, Mihail Lucian Pascu   +7 more
doaj   +1 more source

Modulation of cerebral blood flow and cognition by hyperthermia and hypoxia: An electroencephalographic event‐related potentials perspective

Experimental Physiology, EarlyView.
Abstract Cerebral blood flow (CBF) is essential for sustaining neuronal metabolism and cognitive performance; however, the precise relationship between perfusion and cognition remains unclear. Although ageing and disease are associated with progressive declines in CBF and cognitive impairment, the acute effects of altered CBF under environmental ...
Hiroki Nakata, Shigehiko Ogoh, Manabu Shibasaki   +2 more
wiley   +1 more source

Theoretical model of interstitial diffusion in solid solution under hypergravity conditions

AIP Advances
Diffusion of atoms and molecules is usually driven by concentration gradients, with the influence of gravitational energy being negligible. However, for alloying components operating at exceptional rotational speeds, such as engine blades, the resulting ...
Changyou Li, He Zhang, Haifei Zhan, Chaofeng Lü   +3 more
doaj   +1 more source

Hypergravity-induced malfunction was moderated by the regulation of NMDA receptors in the vestibular nucleus

Scientific Reports, 2021
Gravity alteration is one of the critical environmental factors in the space, causing various abnormal behaviors related with the malfunctioned vestibular system. Due to the high plastic responses in the central vestibular system, the behavioral failures
Gyutae Kim, Kyu-Sung Kim
doaj   +1 more source

Stability of Antimicrobial Drug Molecules in Different Gravitational and Radiation Conditions in View of Applications during Outer Space Missions

Molecules, 2021
The evolution of different antimicrobial drugs in terrestrial, microgravity and hypergravity conditions is presented within this review, in connection with their implementation during human space exploration.
Ágota Simon, Adriana Smarandache, Vicentiu Iancu, Mihail Lucian Pascu   +3 more
doaj   +1 more source

The Hormetic Effects of Hypergravity on Longevity and Aging [PDF]

Dose-Response, 2006
This paper reviews the literature on the effects of hypergravity (HG, gravity levels higher than 1g, the terrestrial gravity) on longevity and aging. The different studies showed that life-long exposures to high gravity levels decreased longevity and accelerated the age-related decline observed on some physiological and behavioral variables.
openaire   +3 more sources

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

Hyper‐buoyancy flotation increases cervical disc height and reduces vertebral stiffness, with only partial reversal after acute 1 g axial loading

Experimental Physiology, EarlyView.
Abstract Exposure to microgravity is associated with stature increases, moderate‐to‐severe back/neck pain and elevated lumbar and cervical intervertebral disc (IVD) herniation risk post‐flight. Whilst lumbar pathophysiology has been investigated, little attention has been placed on the cervical spine.
D. Marcos‐Lorenzo, P. Hernández Bernal, R. Fernández Corujo, A. Gil Martínez, J. Swanenburg, D. A. Green   +5 more
wiley   +1 more source

Mechanisms of haemoglobin mass expansion following heat stress

The Journal of Physiology, EarlyView.
Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins, Brittany A. Edgett, Michael G. Hughes, Joshua C. Tremblay, Mike Stembridge   +4 more
wiley   +1 more source