Results 91 to 100 of about 30,982 (276)
This Mendelian randomization study indicates that specific drinking habits influence the risk of senile cataract (SC) through inflammatory modulation. Genetic analyses revealed that, compared to consuming alcohol apart from meals, alcohol intake aligned with meals reduces the risk of SC among current drinkers, partially through lowered inflammation ...
Jian Deng +6 more
wiley +1 more source
Risk Factors for Cardiovascular and Metabolic Disease: Integrating Traditional and Novel Paradigms
ABSTRACT Cardiovascular and metabolic diseases (CVMD), encompassing atherosclerotic cardiovascular disease (ASCVD), heart failure, obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD), remain the leading global cause of morbidity and mortality.
Zhihua Wang +3 more
wiley +1 more source
Homocysteine and cardiovascular disease
Hyperhomocysteinemia is a condition which , in the absence of kidney disease , indicates a disturpted sulfur amino acid metabolism , either because of vitamin deficiency (folate , B12 and B6 ) or a genetic defect. Epidemiologicevidence suggests that mild
p yavari
doaj
Hyperhomocysteinemia in liver cirrhosis: mechanisms and role in vascular and hepatic fibrosis [PDF]
Numerous clinical and epidemiological studies have identified elevated homocysteine levels in plasma as a risk factor for atherosclerotic vascular disease and thromboembolism.
Arias, R. (Roberto) +8 more
core +1 more source
Anesthetic management of a pediatric patient with methylmalonic acidemia combined with hyperhomocysteinemia: A case report [PDF]
Yunting Pang +3 more
openalex +1 more source
Hypoxia induces HMGB1's nucleus‐to‐cytoplasm translocation, which binds to Nrf2 to repress Nrf2 nuclear translocation to suppress Nrf2/HO‐1 activation to promote NLRP3 inflammasome/Caspase‐1‐mediated pyroptosis, thereby exacerbating MIRI. ABSTRACT Objective Myocardial ischemia–reperfusion injury (MIRI) represents an inevitable risk event for acute ...
Fuzhen Zheng +7 more
wiley +1 more source
Economic Impact of Hyperhomocysteinemia in Switzerland [PDF]
Summary: Since more than 20 years elevated homocysteine plasma levels have been associated with an elevated cardiovascular risk. It can be assumed that approx. 5-7% of the Swiss population suffers from hyperhomocysteinemia.
Käser, Andreas +2 more
core
Elevated homocysteine results from genetic variants, impaired one‐carbon metabolism, nutritional deficiencies, and metabolic disorders. Hyperhomocysteinemia drives oxidative stress, inflammation, excitotoxicity, and epigenetic disruption, affecting multiple organs and systems.
Osmar Vieira Ramires Júnior +5 more
wiley +1 more source
Hyperhomocysteinemia - An unidentified risk factor for stroke in our population [PDF]
Introduction: Various studies show that moderate elevation of plasma homocysteine level has been associated with increased risk for cardiovascular and cerebrovascular disease.
Alvi, Shafaq +3 more
core +1 more source
Serum Homocysteine Levels and its Methylenetetrahydrofolate Gene (MTHFR) C677t Polymorphism in Patients with Hemodialysis [PDF]
Homocysteine plays an important role in cardiovascular disease as an independent risk factor, especially in patients with renal insufficiency. The present study aimed to determine whether Hcy levels, or those of its C677T polymorphism, were associated ...
ALMONACID URREGO, CARMEN CECILIA +17 more
core +1 more source

