Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells [PDF]
, 2019 Modern molecular medicine demands techniques to efficiently deliver molecules directly into mammalian cells. As proteins are the final mediators of most cellular pathways, efficient intracellular protein delivery techniques are highly desired.
Braeckmans, Kevin +10 more
core +2 more sources
Biologia Plantarum, 2010 Hypericin, a naphthodianthrone, has been identified as the principal active compound found in St. John's wort (Hypericum perforatum L.). To generate a gene resource for hypericin and other valuable metabolites, we generated expressed sequence tags (ESTs)
M. L. Jin +5 more
doaj +1 more source
Clinical Medicine Insights: Case Reports, 2023 This case report describes the sudden presentation and successful cessation of psychiatric symptoms following the first administration of the Moderna mRNA vaccine against the SARS-CoV-2 virus during early 2021.
Daniel S Helman
doaj +1 more source
Arbuscular mycorrhizal fungi altered the hypericin, pseudohypericin, and hyperforin content in flowers of Hypericum perforatum grown under contrasting P availability in a highly organic substrate [PDF]
, 2016 St. John’s Wort (Hypericum perforatum) is a perennial herb able to produce water-soluble active ingredients (a.i.), mostly in flowers, with a wide range of medicinal and biotechnological uses.
CARRUBBA, Alessandra +4 more
core +1 more source
The Promise of Solid Lubricants for a Sustainable Future
Advanced Materials, Volume 38, Issue 8, 6 February 2026.Lubricants are vital for technology, saving energy and resources. The industry seeks sustainable solutions beyond fossil fuels. Solid lubricants offer extremely low friction and reduce environmental impact, especially in harsh conditions. Can these solids truly replace liquid lubricants, or are they limited to extreme applications?
Philipp G. Grützmacher +7 more
wiley +1 more source
Usporedna fitokemijska i antimikrobna istraživanja širokolisne i uskolisne rupičaste pljuskavice [Hypericum perforatum L. subsp. perforatum et H. perforatum subsp. angustifolium (DC.) Gaudin] [PDF]
, 2006 The aerial parts of H. perforatum subsp. perforatum and H. perforatum subsp. angustifolium were investigated for their chemical composition and antimicrobial activity. Spectrophotometric analysis indicated that H. perforatum subsp.
ADELHEID H. BRANTNER +4 more
core +3 more sources
Variation in quantitative yield and hypericin content of St. John’s wort., Hypericum perforatum L.
Journal of Medicinal Plants, 2004 St John’s wort, Hypericum Perforatum L. (Culsiaceae) is an important medicinal plant, which has different bioactive constituents and hypericin (a naphtodianthrone) is one of this compounds.
H Naghdi Badi +6 more
doaj
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, Volume 8, Issue 1, Page 231-244, January 2026.Besides being important components of landscape‐level biodiversity, medicinal plants are essential resources for traditional and modern healthcare. However, human‐driven biodiversity loss has resulted in the decline of medicinal plant populations. By maintaining connections between nature, culture, and people, sacred natural sites can help counteract ...
Rita Engel +4 more
wiley +1 more source
Comparative transcriptome reconstruction of four Hypericum species focused on hypericin biosynthesis
Frontiers in Plant Science, 2016 Next generation sequencing technology (NGS) rapidly developed research applications in thefield of plant functional genomics. Several Hypericum spp. with an aim to generate andenhance gene annotations especially for genes coding the enzymes supposedly ...
Miroslav Soták +6 more
doaj +1 more source