Results 61 to 70 of about 8,749 (218)

Quality Control of Hypericum perforatum L. Analytical challenges and recent progress [PDF]

, 2017
Objectives The most widely applied qualitative and quantitative analytical methods in the quality control of Hypericum perforatum extracts will be reviewed, including routine analytical tools and most modern approaches.
Anastasia Agapouda, Ang CYW, Anthony Booker, Anyzewska MM, Dezső Csupor, Freytag WE, Gray DE, Hazler Pilepić K, Judit Hohmann, Michael Heinrich, Nichita C, Powdered St. John's Wort, Robson NKB, Smelcerovic A, Tewari N, Tewari N, Tivadar Kiss, Zhu B   +17 more
core   +3 more sources

Hypericin enhances superlubricity of glycerol by acting as graphene precursor

Friction
Hypericin (C30H16O8) is a naturally occurring substance, an anthraquinone derived from St. John’s wort, possessing outstanding antiviral, antitumor, antibacterial, and antioxidant properties.
Paul Marie Zubieta-Laborde, Yun Long, Thomas Lubrecht, Graham L. W. Cross, Frédéric Dubreuil, Jean Michel Martin, Maria Isabel De Barros Bouchet   +6 more
doaj   +1 more source

Hypericin, a potential new BH3 mimetic

Frontiers in Pharmacology, 2022
Many types of cancer such as prostate cancer, myeloid leukemia, breast cancer, glioblastoma display strong chemo resistance, which is supported by enhanced expression of multiple anti-apoptotic Bcl-2, Bcl-XL and Mcl-1 proteins. The viable anti-cancer strategies are based on developing anti-apoptotic Bcl-2 proteins inhibitors, BH3 mimetics. Our focus in
Anastasia Doroshenko, Silvia Tomkova, Tibor Kozar, Katarina Stroffekova   +3 more
openaire   +3 more sources

Extraction isolation of hypericins from particular kinds of St. john's wort (hypericum perforatum) [PDF]

, 2012
The paper deals with development of the effective mode of isolation of hypericins from St. John's Wort including Soxhlet extraction with ethanol as a solvent. In Central Botanical Garden of the NAS of the RB were found out the kinds of St. John's Wort,
Kovalenko, N. A., Leontiev, V. N., Stasevich, O. V., Supichenko, G. N.   +3 more
core  

Hypericum androsaemum water extract inhibits proliferation in human colorectal cancer cells through effects on MAP kinases and PI3K/Akt pathway [PDF]

, 2012
MAP kinase and PI3K/Akt signalling pathways are commonly altered in colorectal carcinoma (CRC) leading to tumor growth due to increased cell proliferation and inhibition of apoptosis. Several species of the genus Hypericum are used in Portugal to prepare
Ferreira, Manuel Fernandes, Lima, Cristóvão F., Wilson, Cristina Pereira, Xavier, Cristina P. R.   +3 more
core   +1 more source

Hypericin in photobiological assays: An overview

Photodiagnosis and Photodynamic Therapy, 2021
Hypericin is considered a potent photosensitizer for use in antitumor and antimicrobial photodynamic therapy (PDT). This review presents the primary biological results obtained with hypericin in photodynamic therapy applications, such as photodynamic cancer treatment, photoinactivation of microorganisms (PDI), tissue scarring, and photo diagnosis.
Gislaine Patricia, de Andrade, Thaiza Ferreira Menegassi, de Souza, Giselle, Cerchiaro, Maria Aparecida da Silva, Pinhal, Anderson Orzari, Ribeiro, Manoel João Batista Castello, Girão   +5 more
openaire   +2 more sources

Nanoenabled Phytochemical Mining: Gold Nanoparticle‐Mediated Recovery of Low‐Polar Secondary Metabolites From Plant Extract

Small Structures, Volume 7, Issue 3, March 2026.
Green‐synthesized gold nanoparticles serve as tunable nanoadsorbents for selectively enriching low‐polarity secondary metabolites from Hypericum perforatum extracts. Structure‐ and polarity‐dependent interactions, optimized by solvent composition and incubation time, enable efficient recovery of phloroglucinols and xanthones for phytochemical ...
Matam Pradeep, Suman Kalyan Sahoo, Dibyendu Mondal, Gregory Franklin   +3 more
wiley   +1 more source

Recent Advances in Homogeneous Metal-Catalyzed Aerobic C–H Oxidation of Benzylic Compounds [PDF]

, 2018
Csp(3)-H oxidation of benzylic methylene compounds is an established strategy for the synthesis of aromatic ketones, esters, and amides. The need for more sustainable oxidizers has encouraged researchers to explore the use of molecular oxygen.
Domínguez Pérez, Pilar Esther, Herrero Corral, María Teresa, San Martín Faces, Raúl, Urgoitia Gabikaetxebarria, Garazi   +3 more
core   +3 more sources

Photodynamic proprieties of Hypericin and its aqueous soluble derivative Glucamine-Hypericin

Photodiagnosis and Photodynamic Therapy, 2015
s / Photodiagnosis and Photodynamic Therapy 12 (2015) 325–375 351 for low and high light dose, respectively for Vero and HEp-2. The results suggest that HY-G may be as potent photosensitizer as HY with the advantage of being more soluble. Acknowledgements: CEPOF, CAPES, FAPESP. http://dx.doi.org/10.1016/j.pdpdt.2015.07.102 Cellular distribution and PDT
Joyce L.S. Gonçalves, Claudia Bernal, Anderson O. Ribeiro, Janice R. Perussi, Hidetake Imasato   +4 more
openaire   +1 more source

Enhanced hypericin production in Hypericum perforatum and Hypericum pruinatum in response to inoculation with two fungal pathogens

Plant Protection Science, 2005
Recent years has seen increasing interest in the genus Hypericum because it is the source of a variety of compounds and the biological activities of the genus are mainly derived from its hypericin content.
Cüneyt Çirak, Hasan Murat Aksoy, Ali Kemal Ayan, Sağlam Birsen, Kevseroğlu Kudret   +4 more
doaj   +1 more source