Results 81 to 90 of about 2,331 (162)

Hypericin as a non-antioxidant inhibitor of NF-κB

, 1999
NF-κB is a transcription factor involved in immune and inflammatory responses. Here we show that micromolar concentrations of hypericin inhibited the PMA- and TNF-α-induced activation of NF-κB in HeLa and TC10 cells, respectively.
Schmitz, ML L, Bacher, S, Kaspers, U, Heinrich, M., Bork, PM M   +4 more
core   +1 more source

Inhibition of dengue virus type 2 by hypericin mediated through viral envelope protein interaction

Virology Journal
Background Dengue fever continues to exert significant global impact, affecting populations worldwide with considerable public health and economic consequences. There is no antiviral drug for dengue. This study focuses on hypericin, a naturally occurring
Lianxin Qi, Meiling Tang, Libo Liu, Jinzhi Cheng, Qiuqiu Xiao, Jianfei Qiu, Jiahong Wu   +6 more
doaj   +1 more source

L., Crantz., L. and L.: Phytochemical and Morphological Studies

Natural Product Communications, 2006
Four species of Hypericum growing in Italy were characterized morphologically and chemically: Hypericum perforatum L., H. maculatum Crantz., H. calycinum L. and H. pulchrum L. The composition of secondary metabolites (phloroglucinols, naphthodianthrones,
Gelsomina Fico, Sara Vitalini, Noemi Colombo, Franca Tomè   +3 more
doaj   +1 more source

Does hypericin boost the efficacy of high-power laser? A preliminary experimental study on rats

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Lasers are widely used in treating symptomatic benign prostatic hyperplasia. In current practice, potassium titanyl phosphate (KTP) lasers are the most common type of laser systems used.
Murat Zor, Serdar Goktas, Ibrahim Yildirim, Unal Orhan Zorba, Seref Basal, Bilal Firat Alp, Engin Kaya, Osman Erogul   +7 more
doaj   +1 more source

Comparison of hypericin content, antioxidant, antimicrobial and cytotoxic activities of Hypericum perforatum L. from three geographic regions of Iran

مجله دانشگاه علوم پزشکی گرگان, 2017
Background and Objective: Hypericin is found in different species of Hypericum genus, as a main compound with antimicrobial, antiviral, nonspecific kinas inhibition and dopamin β-hydroxilase inhibitoring effects.
M Akhbari, M Ebrahimian
doaj  

Hypericin Nanoparticles-Associated Photodynamic Therapy Modulates the Biological Behavior of Hepatocellular Carcinoma by SERPINE1 [PDF]

Xuanzhi Yan,1,* Jiaxing Fan,1,* Wanying Qin,1,* Minjun Liao,1,2,* Siming Li,1 Liya Suo,1 Yujin Xie,1 Xin Jiang,3 Dengfeng Zou,4 Weijia Liao1 1Laboratory of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical ...
Suo L, Li S, Xie Y, Fan J, Jiang X, Liao W, Qin W, Zou D, Yan X, Liao M   +9 more
core  

Hypericin repairs misregulated splicing events associated with myotonic dystrophy in type 1 myoblast lines

Genetics & Applications
Myotonic dystrophy is associated with the molecular event of misregulated splicing of a subset of RNAs, which contribute to some of the disease phenotypes.
Inyang Udofia Udosen, Monday Isaiah Akpanabiatu, Usenobong Friday Ufot   +2 more
doaj   +1 more source

Compatibility study of topical 0.25% hypericin (HyBryteTM) application in subjects with mycosis fungoides: Results of the HPN‐CTCL‐02 study

JEADV Clinical Practice
Background HyBryteTM is a photodynamic therapy of topical hypericin that has recently been shown to be safe and efficacious in early stage cutaneous T‐cell lymphoma (CTCL).
Carolina V. Alexander‐Savino, Adam Rumage, Christopher Pullion, Richard Straube, Christopher J. Schaber, Elaine S. Gilmore, Brian Poligone   +6 more
doaj   +1 more source

Effects of hypericin on human renal carcinoma cells in vitro

, 2010
Das Gewöhnliche Johanniskraut (Hypericum perforatum L.) ist eine seit der Antike bekannte Heilpflanze. Einer seiner Inhaltsstoffe, das so genannte Hypericin, ist namensgebend für diese Pflanzengattung und wird in
Busse, Ann-Christin
core   +1 more source

Hairy Root Cultures of Hypericum perforatum L.; A Promising Method for The High Scale Production of Hypericin

Journal of Medicinal Plants, 2018
Background: Biotechnologic methods are common for secondary metabolites production from the plants and other sources in pharmaceutical sciences. Hairy root cell lines as the biotechnologic method have been used for in vitro production of major plant ...
M Montazeri M (M.Sc.), M Azadbakht, H Najafi Zarrini, GhA NematZadeh, A Pakdin Parizi, A Davoodi   +5 more
doaj