Results 41 to 50 of about 8,749 (218)

St John’s wort (Hypericum perforatum) products – an assessment of their authenticity and quality [PDF]

open access: yes, 2018
St John’s wort products (Hypericum perforatum L.) are widely available for sale in many countries including the UK via the internet. In the UK, these products are required to hold either a marketing authorisation or Traditional herbal registration (THR ...
Agapouda, A.   +11 more
core   +2 more sources

Photoactivated hypericin is not genotoxic

open access: yesGeneral physiology and biophysics, 2016
The study was designed to test the potential photogenotoxicity of hypericin (HYP) at three different levels: primary DNA damages, gene mutations and chromosome aberrations. Primary genetic changes were detected using the comet assay. The potential mutagenic activity of HYP was assessed using the Ames/Salmonella typhimurium assay.
Jana, Feruszová   +7 more
openaire   +3 more sources

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

Seasonal Variation of Hypericin and Pseudohypericin Contents in L. Growing Wild in Turkey

open access: yesNatural Product Communications, 2008
The present study was conducted to determine ontogenetic and morphogenetic variations of hypericin and pseudohypericin contents in Hypericum scabrum growing in Turkey.
Ali Kemal Ayan   +2 more
doaj   +1 more source

Theoretical and Experimental Evidence of Two‐Step Tautomerization in Hypericin

open access: yesAdvanced Photonics Research, 2021
Hypericin has large potential in modern medicine and exhibits fascinating structural dynamics, such as multiple conformations and tautomerization. However, it is difficult to study individual conformers/tautomers, as they cannot be isolated due to the ...
Quan Liu   +7 more
doaj   +1 more source

A New UHPLC Analytical Method for St. John’s Wort (Hypericum perforatum) Extracts

open access: yesSeparations, 2023
Commonly used to treat mood disorders, St. John’s Wort (Hypericum perforatum) is a popular herb in the natural health products industry. The potency of its active ingredients can be determined using a number of different analytical methods, but it is ...
Lisa Wang   +3 more
doaj   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

open access: yesBMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo   +9 more
wiley   +1 more source

Agents for fluorescence-guided glioma surgery: a systematic review of preclinical and clinical results [PDF]

open access: yes, 2016
Background: Fluorescence-guided surgery (FGS) is a technique used to enhance visualization of tumor margins in order to increase the extent of tumor resection in glioma surgery.
Aditya V. Karhade   +6 more
core   +2 more sources

Advancements in Inorganic Chiral Nanomaterials for Anti‐Tumor Immunotherapy

open access: yesCancer Science, EarlyView.
Schematic illustration of how inorganic chiral nanomaterials enhance immune activation to promote tumor cell elimination through targeted delivery, immunogenic cell death, and immune microenvironment modulation. ABSTRACT While the past decade has witnessed unprecedented technological advancements, cancer remains a major health threat, with conventional
Siyu Chen   +9 more
wiley   +1 more source

In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library

open access: yesPharmaceuticals, 2022
The main protease (Mpro or 3CLpro) in coronaviruses represents a promising specific drug target as it is essential for the cleavage of the virus polypeptide and has a unique cleavage site that does not exist in human host proteases.
Nasim Shahhamzehei   +2 more
doaj   +1 more source

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