Results 31 to 40 of about 8,749 (218)

Clinical Assessment of the Effect of Hypericum perforatum Chewing Gum on Salivary Streptococcus mutans Count, pH, Plaque Index, and Gingival Bleeding: A Randomized Clinical Trial. [PDF]

Clin Exp Dent Res
ABSTRACT Objectives Hypericum perforatum L. offers several beneficial effects, for example antioxidant, antitumor, wound healing. Our aim was to ascertain the effect of H. perforatum extract gum on salivary Streptococcus mutans count, pH, plaque index, and gingival bleeding. Materials and Methods A total of 54 participants were assigned into two groups
Jamali A, Hamishehkar H, Memar MY, Mousavi Kalajahi SE, Kouhsoltani M, Kosari-Nasab M.   +5 more
europepmc   +2 more sources

Endocrinological effects of high-dose Hypericum perforatum extract WS 5570 in healthy subjects [PDF]

, 2004
In this single-blind study, the effects of acute oral administration of high-dose Hypericum perforatum extract WS 5570 on the cortisol ( COR), adrenocorticotropic hormone ( ACTH), growth hormone (GH), and prolactin (PRL) secretions were examined in 12 ...
Baghai, Thomas C., Laakmann, G., Sauer, N., Schule, C.   +3 more
core   +1 more source

Pre-clinical Evaluation of a Cyanine-Based SPECT Probe for Multimodal Tumor Necrosis Imaging [PDF]

, 2016
Purpose: Recently we showed that a number of carboxylated near-infrared fluorescent (NIRF) cyanine dyes possess strong necrosis avid properties in vitro as well as in different mouse models of spontaneous and therapy-induced tumor necrosis, indicating ...
Beek, E.R. (Ermond) van, Bierau, K. (Katja), Chan, A. (Alan), Cordfunke, R.A. (Robert A.), Cruz, L.J. (Luis J.), DaCosta, R.S. (Ralph S.), Dubikovskaya, E.A. (Elena A.), Feitsma, H.R.I.J. (Hans R. I. J.), Kaijzel, E.L. (Eric), Knol-Blankevoort, V.T. (Vicky T.), Löwik, C.W.G.M. (Clemens), Maeda, A. (Azusa), Mezzanotte, L. (Laura), Sinisi, R. (Riccardo), Snoeks, T.J.A. (thomas), Stammes, M.A. (Marieke A.)   +15 more
core   +6 more sources

Enhancing the efficacy of cytotoxic agents for cancer therapy using photochemical internalisation. [PDF]

, 2015
Photochemical internalisation (PCI) is a technique for improving cellular delivery of certain bioactive agents which are prone to sequestration within endolysosomes.
Adigbli, Adigbli, Arentsen, Baglo, Berg, Berg, Berg, Berg, Berstad, Bodles-Brakhop, Bostad, Bostad, Bull-Hansen, Castano, Castano, Chong, Dietze, Dietze, Elisabeth Olsen, Fretz, Gaware, Gooding, Gottesman, Hirschberg, Høgset, Jørgensen, Kunz, Lai, Lai, Lakshmanan, Lou, Lu, Lund, Mathews, Mroz, Mroz, Norum, Norum, Norum, Norum, Pasparakis, Peng, Peng, Prasmickaite, Reginato, Rosenblum, Selbo, Selbo, Selbo, Selbo, Selbo, Selbo, Selbo, Selbo, Selbo, St Denis, Stratford, Todorova, Vikdal, Wang, Wang, Wang, Weyergang, Weyergang, Woodhams, Xu, Yaghini, Yao, Yip, Zahreddine   +69 more
core   +1 more source

Green synthesis and in vitro photodynamic efficacy of hypericin: Cytotoxicity assessment on MCF-7 breast cancer cells

Photodiagnosis and Photodynamic Therapy
Photodynamic therapy (PDT) is a minimally invasive therapy for treating cancers, infectious diseases and several other conditions. It uses light as an activator and component called photosensitizer. Hypericin is a natural photosensitizer which garnered a
Monosha Priyadarshini, N. Arunai Nambi Raj   +1 more
doaj   +1 more source

The Effects of Photosensitizing Dyes Fagopyrin and Hypericin on Planktonic Growth and Multicellular Life in Budding Yeast

Molecules, 2021
Naphthodianthrones such as fagopyrin and hypericin found mainly in buckwheat (Fagopyrum spp.) and St. John’s wort (SJW) (Hypericum perforatum L.) are natural photosensitizers inside the cell.
Oksana Sytar, Konstantia Kotta, Dimitrios Valasiadis, Anatoliy Kosyan, Marian Brestic, Venetia Koidou, Eleftheria Papadopoulou, Maria Kroustalaki, Christina Emmanouilidou, Alexandros Pashalidis, Ilias Avdikos, Zoe Hilioti   +11 more
doaj   +1 more source

Modulation of 5-Aminolevulinic acid mediated photodynamic therapy induced cell death in a human lung adenocarcinoma cell line [PDF]

, 2016
Photodynamic therapy (PDT) is a cancer treatment involving the administration of a photosensitising drug which selectively accumulates in tumor tissue, followed by irradiation with appropriate wavelength light.
Battle, A., Diez, Berenice Andrea, Fukuda, Haydee, Teijo, Maria Julieta   +3 more
core   +2 more sources

Seamlessly Overcoming Biological Barriers with a Small Photosensitizer to Treat Metastatic Tumors with Photodynamic Therapy

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
LUZ 51 is a relatively small and amphiphilic photosensitizer that accumulates in poorly‐vascularized tumors, is rapidly internalized by cancer cells, does not elicit skin photosensitivity and triggers robust immunological responses that reduce spontaneous metastasis.
Mafalda Penetra, Bárbara Lima, João P. A. Campos, Sara M. A. Pinto, Fábio A. Schaberle, Mariette M. Pereira, Luis G. Arnaut, Lígia C. Gomes‐da‐Silva   +7 more
wiley   +2 more sources

MALDI-HRMS Imaging Maps the Localization of Skyrin, the Precursor of Hypericin, and Pathway Intermediates in Leaves of Hypericum Species

Molecules, 2020
Hypericum perforatum and related species (Hypericaceae) are a reservoir of pharmacologically important secondary metabolites, including the well-known naphthodianthrone hypericin.
Bharadwaj Revuru, Miroslava Bálintová, Jana Henzelyová, Eva Čellárová, Souvik Kusari   +4 more
doaj   +1 more source

A Deep‐Red‐Absorbing Osmium(II) Complex as a Photosensitizer for Photodynamic Therapy Inducing Immunogenic Cell Death

Angewandte Chemie International Edition, EarlyView.
A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang, Pierre Mesdom, Eduardo Izquierdo‐García, João P. M. António, Ruonan Gao, Bruno Saubaméa, Johanne Seguin, Morgane Moinard, Philippe Arnoux, Céline Frochot, Kevin Cariou, Bich‐Thuy Doan, Gilles Gasser   +12 more
wiley   +1 more source