Results 11 to 20 of about 5,778 (206)

Hypericin and hypericin-like substances: Analytical problems

, 1998
Abstract Hypericin is a substance derived from Hypericum perforatum L., a plant utilized in the production of extracts used to aromatize alcoholic beverages and soft drinks and limited in food and beverages by the E.E.C. Directives on Flavouring. This paper deals with the H.P.L.C.
F. Tateo, S. Martello, E. Lubian, M. Bononi   +3 more
openaire   +3 more sources

Isolation and functional analysis of cDNAs similar to Hyp-1 involved in hypericin biosynthesis from Hypericum erectum

Biologia Plantarum, 2010
Hypericin, a naphthodianthrone, has been identified as the principal active compound found in St. John's wort (Hypericum perforatum L.). To generate a gene resource for hypericin and other valuable metabolites, we generated expressed sequence tags (ESTs)
M. L. Jin, J. C. Ahn, B. Hwang, H. -S. Park, H. S. Lee, D. -W. Choi   +5 more
doaj   +2 more sources

Hypericin in the light and in the dark: Two sides of the same coin [PDF]

Frontiers in Plant Science, 2016
Hypericin (4,5,7,4',5',7'-hexahydroxy-2,2'-dimethylnaphtodiantrone) is a naturally occurring chromophore found in plants of the genus Hypericum, especially Hypericum perforatum L. (St.
Zuzana eJendzelovska, Rastislav eJendzelovsky, Barbora eKucharova, Peter eFedorocko   +3 more
doaj   +2 more sources

Aromaticity and Electron Density of Hypericin

Journal of Natural Products, 2019
The influence of the substituents on the geometry of the central ring system of hypericin has been analyzed. Substitution that causes flattening of the hypericin central rings is connected with introducing the aromatic character of the empty rings. All the hypericin rings have an aromatic character illustrated by the Harmonic Oscillator Measure of ...
Sebastian Szymanski, Irena Majerz
openaire   +4 more sources

Hypericin enhances superlubricity of glycerol by acting as graphene precursor

Friction
Hypericin (C30H16O8) is a naturally occurring substance, an anthraquinone derived from St. John’s wort, possessing outstanding antiviral, antitumor, antibacterial, and antioxidant properties.
Paul Marie Zubieta-Laborde, Yun Long, Thomas Lubrecht, Graham L. W. Cross, Frédéric Dubreuil, Jean Michel Martin, Maria Isabel De Barros Bouchet   +6 more
doaj   +2 more sources

Properties and Permeability of Hypericin and Brominated Hypericin in Lipid Membranes

Journal of Chemical Theory and Computation, 2009
The promising photosensitizing properties of hypericin, a substituted phenanthroperylene quinone naturally found in Saint John's wort, has led to the proposal that it can be utilized in photodynamic therapy. Structurally modified derivatives are at the present time being investigated to generate a more effective hypericin photosensitizer.
Eriksson, Emma S. E., dos Santos, Daniel J. V. A., Guedes, Rita C., Eriksson, Leif A.   +3 more
openaire   +4 more sources

The Multifaceted Photocytotoxic Profile of Hypericin

Molecular Pharmaceutics, 2009
Photodynamic therapy (PDT) is an established anticancer treatment employing a phototoxin (photosensitizer), visible light and oxygen. The latter is photochemically converted into reactive oxygen species, which are highly toxic to the cells. Hypericin, a natural pigment of hypericum plants, is prominent among photosensitizers. The unique perylenequinone
Theodossis A, Theodossiou, John S, Hothersall, Peter A, De Witte, Alexandros, Pantos, Patrizia, Agostinis   +4 more
openaire   +3 more sources

Hypericin-bearing magnetic iron oxide nanoparticles for selective drug delivery in photodynamic therapy

International Journal of Nanomedicine, 2015
Harald Unterweger,1 Daniel Subatzus,1 Rainer Tietze,1 Christina Janko,1 Marina Poettler,1 Alfons Stiegelschmitt,2 Matthias Schuster,3 Caroline Maake,4 Aldo R Boccaccini,5 Christoph Alexiou11ENT Department, Section of Experimental Oncology and ...
Unterweger H, Subatzus D, Tietze R, Janko C, Poettler M, Stiegelschmitt A, Schuster M, Maake C, Boccaccini AR, Alexiou C   +9 more
doaj   +1 more source

Lipid-Mediated Preferential Localization of Hypericin in Lipid Membranes [PDF]

, 2010
Subcellular localization of a photosensitizer is critical to its therapeutic outcome during photodynamic therapy (PDT). We delineated the distribution of hypericin, a new generation photosensitizer, in model membrane systems to identify the operating ...
何藴芳;吳明煌;陳雅雯;施明智, HO, YUNN-FANG;WU, MING-HUANG;CHEN, YA-WEN;SHIH, MING-CHIH   +1 more
core   +3 more sources

Fluorescence lifetime imaging unravels the pathway of glioma cell death upon hypericin-induced photodynamic therapy [PDF]

, 2023
Malignant primary brain tumors are a group of highly aggressive and often infiltrating tumors that lack adequate therapeutic treatments to achieve long time survival. Complete tumor removal is one precondition to reach this goal.
Marc, Brecht, Tim, Rammler, Rainer, Ritz, Marcus, Scheele, Frank, Wackenhut, Miriam, Bassler, Philipp, Frech, Kai, Braun, Jonas, Hiller, Christoph, Kertzscher, Sven, zur Oven-Krockhaus, Felix, Schmidt, Alfred, J. Meixner   +12 more
core   +2 more sources