Results 21 to 30 of about 2,331 (162)
Different effects of single and fractionated light delivery regimes in photodynamic therapy with hypericin on HT-29 cells in vitro [PDF]
, 2009 Photodynamic therapy (PDT) is an alternative cancer cure which involves the selective uptake and retention of a photosensitizer in a cancer tissue, followed by irradiation with light of a specific wavelength to kill tumour cells via the production of ...
Grada Kulikova, Lucia
core +1 more source
Acta Pharmaceutica Sinica B, 2019 Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection.
Genzhu Wang +8 more
doaj +1 more source
Photodynamic therapy and tumor imaging of hypericin-treated squamous cell carcinoma
World Journal of Surgical Oncology, 2006 Background Conventional cancer therapy including surgery, radiation, and chemotherapy often are physically debilitating and largely ineffective in previously treated patients with recurrent head and neck squamous cell carcinoma (SCC).
Sercarz Joel +3 more
doaj +1 more source
Hypericin in photobiological assays: An overview
Photodiagnosis and Photodynamic Therapy, 2021 Hypericin is considered a potent photosensitizer for use in antitumor and antimicrobial photodynamic therapy (PDT). This review presents the primary biological results obtained with hypericin in photodynamic therapy applications, such as photodynamic cancer treatment, photoinactivation of microorganisms (PDI), tissue scarring, and photo diagnosis.
Gislaine Patricia, de Andrade +5 more
openaire +2 more sources
Spectrofluorimetric determination of hypericin in drugs and vegetable raw materials [PDF]
, 2021 Hypericin was isolated from Diahyperon tincture for use as a standard sample. The chromatographic purity of the hypericin was confi rmed by high-performance liquid chromatography/mass spectrometry.
Kosyak, D. A. +4 more
core +1 more source
An investigation into the cellular mechanisms underlying photodynamic rejuvenation in human skin [PDF]
, 2012 Includes abstract.Includes bibliographical references.Photodynamic Rejuvenation (PDR) is a novel therapy used to treat the signs of skin ageing. It is a promising dermatological therapy due to its less severe side effects and superior results when ...
Van Kets, Victoria Louise
core +1 more source
Angewandte Chemie, Volume 138, Issue 27, 1 July 2026.A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang +12 more
wiley +2 more sources
Photoactivated hypericin is not genotoxic
General physiology and biophysics, 2016 The study was designed to test the potential photogenotoxicity of hypericin (HYP) at three different levels: primary DNA damages, gene mutations and chromosome aberrations. Primary genetic changes were detected using the comet assay. The potential mutagenic activity of HYP was assessed using the Ames/Salmonella typhimurium assay.
Jana, Feruszová +7 more
openaire +3 more sources
Elucidation of the tumoritropic principle of hypericin [PDF]
British Journal of Cancer, 2005 Hypericin is a potent agent in the photodynamic therapy of cancers. To better understand its tumoritropic behaviour, we evaluated the major determinants of the accumulation and dispersion of hypericin in subcutaneously growing mouse tumours. A rapid exponential decay in tumour accumulation of hypericin as a function of tumour weight was observed for ...
Van de Putte, Marie +4 more
openaire +3 more sources
, 2020 Rhabdomyosarkome gehören zu den häufigsten soliden Tumoren des Kindesalters. Besonders der alveoläre Subtyp zeigt ein invasives Wachstum mit frühzeitiger Metastasierung.
Ocker, Lennart Tim +1 more
core +2 more sources