Results 191 to 200 of about 103,854 (365)
ABSTRACT Background and Aims The role of the patatin‐like phospholipase domain‐containing protein 3 (PNPLA3)‐I148M variant in drug‐induced liver injury (DILI) remains unclear. This systematic review with meta‐analysis investigated whether carriage of PNPLA3 I148M may contribute to the development of hepatocellular DILI.
Alexandra Gatzios+6 more
wiley +1 more source
Association between insulin resistance, lean mass and muscle torque/force in proximal versus distal body parts in healthy young men [PDF]
Objectives:The purpose of this study was to investigate whether there is already an association of insulin resistance (IR) with muscle mass and –force/torque in an adult population and whether this relationship is the same in distal and proximal body ...
Calders, Patrick+7 more
core +1 more source
ABSTRACT Pregnancy is a crucial period during which maternal nutrition, weight and lifestyle behaviours have a direct impact on both maternal and fetal health. This briefing paper describes dietary and lifestyle recommendations for women during the preconceptional period and throughout pregnancy, identifying specific factors that can be modified to ...
Kathryn H. Hart+5 more
wiley +1 more source
Hyperinsulinemia as an independent risk factor for ischemic heart disease.
J. Despres+6 more
semanticscholar +1 more source
ABSTRACT Objectives Gestational diabetes mellitus (GDM), affecting one in seven pregnant women worldwide, can have short‐ and long‐term adverse outcomes for both the mother and her baby. Despite a raft of prognostic models aiming to predict adverse GDM outcomes, very few have impacted clinical practice.
Yasmina Al Ghadban+8 more
wiley +1 more source
ABSTRACT Background Existing evidence shows inconsistent associations between preterm birth and childhood obesity. The impact of full gestational age on the risk of childhood obesity and overweight remains unclear. Objectives This systematic scoping review aims to comprehensively explore the relationship between gestational age at birth across the ...
Yuantao Su+4 more
wiley +1 more source
Alternative Splicing Regulation in Metabolic Disorders
ABSTRACT Alternative splicing (AS) is a fundamental mechanism for enhancing transcriptome diversity and regulating gene expression, crucial for various cellular processes and the development of complex traits. This review examines the role of AS in metabolic disorders, including obesity, weight loss, dyslipidemias, and metabolic syndrome.
Dorota Kaminska
wiley +1 more source
Blood pressure response to hyperinsulinemia in salt-sensitive and salt-resistant rats.
Hirofumi Tomiyama+9 more
openalex +1 more source
Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice [PDF]
Atsuko Kushi+5 more
openalex +1 more source
The positive influence of berberine on the nervous system can be attributed to its diverse effects on multiple targets. The effects of berberine include its antioxidant, anti‐apoptotic, anti‐necroptotic, and anti‐inflammatory properties, as well as its ability to induce autophagy.
Xiaolan Wang+5 more
wiley +1 more source