Among patients with acute ischemic stroke achieving successful large vessel recanalization (defined as expanded Thrombolysis in Cerebral Infarction [eTICI ≥2b]), incomplete tissue‐level reperfusion, distinct from visually identifiable distal occlusion on digital‐subtraction angiography, remains a significant challenge.
Yue Qiao +4 more
wiley +1 more source
IntroductionThis study investigates the association between white matter hyperintensities (WMH), specifically periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH), and the prognosis and recurrence risk in patients with ...
Hongwei Ren +7 more
doaj +1 more source
Recent Insights Into Alzheimer's Disease: Advances in Pathophysiology and Therapeutic Strategies
ABSTRACT Alzheimer's disease (AD) is a complex neurodegenerative disorder driven by interplay among amyloid‐β (Aβ) plaques, tau neurofibrillary tangles, inflammation and comorbid pathologies. Recent advances in biomarkers and therapeutic approvals have reshaped our understanding of its pathophysiology and treatment landscape.
Jiong Shi +3 more
wiley +1 more source
Uterine smooth muscle neoplasms that cannot be clearly diagnosed as benign or malignant based on generally applied histopathologic parameters are classified as “smooth muscle tumors of uncertain malignant potential (STUMP)”.
Kyung Ho Kim +4 more
doaj +1 more source
Restriction Spectrum Imaging Differentiates True Tumor Progression From Immune-Mediated Pseudoprogression: Case Report of a Patient With Glioblastoma. [PDF]
Immunotherapy is increasingly used in the treatment of glioblastoma (GBM), with immune checkpoint therapy gaining in popularity given favorable outcomes achieved for other tumors.
Bahrami, Naeim +9 more
core
ABSTRACT Introduction Tumefactive demyelinating lesions (TDLs) are large lesions (> 2 cm) seen in demyelinating syndromes such as multiple sclerosis, myelin oligodendrocyte glycoprotein antibody‐associated disorder, and neuromyelitis optica spectrum disorder. They rarely occur in children and most often have a monophasic course.
Elizabeth C. Ballinger +6 more
wiley +1 more source
Loss of Integrity of Corpus Callosum White Matter Hyperintensity Penumbra Predicts Cognitive Decline in Patients With Subcortical Vascular Mild Cognitive Impairment [PDF]
Yage Qiu +8 more
openalex +1 more source
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
A New Visual Scale to Assess White Matter Hyperintensities Within Cholinergic Pathways [PDF]
Mikołaj A. Pawlak, Jarosław Krejza
openalex +1 more source
Association of RNF213 polymorphism and cortical hyperintensity sign on fluid-attenuated inversion recovery images after direct revascularization surgery for moyamoya disease: possible involvement of intrinsic vascular vulnerability [PDF]
Haruto Uchino +6 more
openalex +1 more source

