Results 211 to 220 of about 61,809 (286)

ASL 4D MRA Intracranial Vessel Segmentation With Deep Learning U‐Nets

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 2384-2396, April 2026.
ABSTRACT Purpose To propose a spatio‐temporal U‐Net based network (4DST) that exploits both spatial and dynamic information while avoiding memory‐intensive 4D convolutional layers for ASL‐based non‐contrast enhanced 4‐dimensional MR angiography (4D MRA) vessel segmentation.
Sang Hun Chung   +7 more
wiley   +1 more source

Marchiafava-Bignami disease mimicking acute corpus callosum infarction associated with chronic shochu consumption. [PDF]

open access: yesSurg Neurol Int
Michiwaki Y   +8 more
europepmc   +1 more source

Multimodal MRI Reveals Cerebral and Vascular Amyloid‐Driven Myeloarchitectural Disorganization in a Mouse Model of Alzheimer's Disease

open access: yesNMR in Biomedicine, Volume 39, Issue 4, April 2026.
This study investigates the effect of cerebral and vascular (beta‐amyloid) Aβ on regional myeloarchitecture and lipid composition in a murine model of Alzheimer's disease (AD). The study highlights the feasibility of quantitative MRI and chemical exchange saturation transfer (CEST) imaging to identify multiple biophysical mechanisms involved in ...
Syed Salman Shahid   +7 more
wiley   +1 more source

The role of neuroimaging in neurotoxicity after chimeric antigen receptor T-cell therapy. [PDF]

open access: yesTher Adv Neurol Disord
Lasocki A   +3 more
europepmc   +1 more source

Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency

open access: yesClinical Genetics, Volume 109, Issue 4, Page 784-787, April 2026.
We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou   +3 more
wiley   +1 more source

An Autopsy Case With Fragile X‐Associated Tremor/Ataxia Syndrome Presenting Intranuclear Inclusion Bodies Mainly in the Limbic System

open access: yesNeuropathology, Volume 46, Issue 2, April 2026.
ABSTRACT Fragile X‐associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder characterized by a late onset and slow progression caused by a premutation (55–200 CGG repeat) in the fragile X mental retardation (FMR1) gene. Here, we report the case of a Japanese patient with FXTAS which is the first case autopsied in Japan. The patient was
Ayako Shioya   +5 more
wiley   +1 more source

NOTCH3 CADASIL Variant Receptor Aggregation Requires NOTCH3 Wild‐Type Receptors: Identification of Highly Selective Inhibitors That Block the Process

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
CADASIL is the major cause of early‐onset stroke and cognitive dysfunction, including dementia. It is caused by mutations in the NOTCH3 receptor that result in the formation of protein aggregates in the small vessel walls of the brain. We demonstrated that NOTCH3 CADASIL variant receptor aggregation is strictly dependent on interactions with NOTCH3 ...
Haijiang Wang   +9 more
wiley   +1 more source

Examining neuroimaging biomarkers, plasma biomarkers and cognitive functions in patients with recovered COVID-19 infection: a multicentre study using 7T MRI. [PDF]

open access: yesBrain Commun
Liou JJ   +30 more
europepmc   +1 more source

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