Results 31 to 40 of about 66,395 (336)

Brain White Matter Structure and Amyloid Deposition in Black and White Older Adults: The ARIC‐PET Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background White matter abnormalities are a common feature of aging and Alzheimer disease, and tend to be more severe among Black individuals. However, the extent to which white matter abnormalities relate to amyloid deposition, a marker of Alzheimer ...
Keenan A. Walker, Noah Silverstein, Yun Zhou, Timothy M. Hughes, Clifford R. Jack, David S. Knopman, A. Richey Sharrett, Dean F. Wong, Thomas H. Mosley, Rebecca F. Gottesman   +9 more
doaj   +1 more source

Neuroticism and white matter hyperintensities

Journal of Psychiatric Research, 2023
Neuroticism is a major risk factor for neurodegenerative disorders, such as Alzheimer's disease and related dementias. This study investigates whether neuroticism is associated with white matter hyperintensities and whether this measure of brain integrity is a mediator between neuroticism and cognitive function. Middle-aged and older adults from the UK
Antonio Terracciano, Bertin Cenatus, Xianghe Zhu, Selin Karakose, Yannick Stephan, Sofia Marcolini, Peter P. De Deyn, Martina Luchetti, Angelina R. Sutin   +8 more
openaire   +4 more sources

Visible T1-hyperintensity of the dentate nucleus after multiple administrations of macrocyclic gadolinium-based contrast agents: yes or no?

Insights into Imaging, 2019
Objectives To investigate the appearance of visible dentate nucleus (DN) T1-hyperintensity and quantify changes in DN/pons (DN/P) signal intensity (SI) ratio in MS patients after the exclusive administration of macrocyclic GBCAs.
Alessandra Splendiani, Antonella Corridore, Silvia Torlone, Milvia Martino, Antonio Barile, Ernesto Di Cesare, Carlo Masciocchi   +6 more
doaj   +1 more source

Resting state connectivity and cognitive performance in adults with cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy [PDF]

, 2016
Cognitive impairment is an inevitable feature of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), affecting executive function, attention and processing speed from an early stage.
Cullen, Breda, Kalladka, Dheeraj, Krishnadas, Rajeev, López-González, Maria R., Moreton, Fiona C., Muir, Keith W., Santosh, Celestine, Schwarzbauer, Christian, Stringer, Michael S.   +8 more
core   +1 more source

Diffusion Tensor Imaging Evaluation of Corticospinal Tract Hyperintensity in Upper Motor Neuron-Predominant ALS Patients

Journal of Aging Research, 2011
Amyotrophic lateral sclerosis (ALS) patients with predominant upper motor neuron (UMN) signs occasionally have hyperintensity of corticospinal tract (CST) on T2- and proton-density-(PD-) weighted brain images.
Venkateswaran Rajagopalan, Didier Allexandre, Guang H. Yue, Erik P. Pioro   +3 more
doaj   +1 more source

Imaging Spectrum of the Developing Glioblastoma: A Cross-Sectional Observation Study

Current Oncology, 2023
Glioblastoma (GBM) has the typical radiological appearance (TRA) of a centrally necrotic, peripherally enhancing tumor with surrounding edema. The objective of this study was to determine whether the developing GBM displays a spectrum of imaging changes ...
Stuart Currie, Kavi Fatania, Russell Frood, Ruth Whitehead, Joanna Start, Ming-Te Lee, Benjamin McDonald, Kate Rankeillor, Paul Roberts, Aruna Chakrabarty, Ryan K. Mathew, Louise Murray, Susan Short, Andrew Scarsbrook   +13 more
doaj   +1 more source

Age Related Changes in Cerebrovascular Reactivity and Its Relationship to Global Brain Structure [PDF]

, 2015
ACKNOWLEDGMENTS This study was funded by Alzheimer’s Research UK (ARUK) and the Aberdeen Biomedical Imaging Centre, University of Aberdeen. GDW, ADM and CS are part of the SINASPE collaboration (Scottish Imaging Network - A Platform for Scientific ...
Ahearn, Trevor S., Cameron, George G., Murray, Alison D., Schwarzbauer, Christian, Waiter, Gordon D.   +4 more
core   +1 more source

Periventricular Hyperintensities Mimicking Multiple Sclerosis [PDF]

Cureus, 2019
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a small-to-medium-sized vessel disease that causes degeneration of vascular smooth muscles. The most frequently found mutation is NOTCH3 on chromosome 19, the presence of which confirms the diagnosis of CADASIL.
Saleem, Sidra, Anwar, Arsalan, Abbasi, Zainab, Anjum, Zauraiz, Tariq, Zemal   +4 more
openaire   +2 more sources

Clinical presentation, diagnostic findings and outcome of dogs with presumptive spinal-only meningoencephalomyelitis of unknown origin [PDF]

, 2017
Objectives: To summarise clinical presentation, diagnostic findings and long-term outcome for dogs clinically diagnosed with meningoencephalomyelitis of unknown origin affecting the spinal cord alone.
Cardy, Coates, Csebi, Da Costa, De Risio, Dewey, Eminaga, Fenn, Granger, Griffin, Meric, Parry, Scott, Tipold   +13 more
core   +2 more sources

A case of chronic subdural hematoma demonstrating the epileptic focus at the area with sulcal hyperintensity on fluid-attenuated inversion recovery image

Radiology Case Reports, 2019
Although the sulcal hyperintensity on fluid-attenuated inversion recovery (FLAIR) images is detected in some chronic subdural hematoma (CSDH) cases, its clinical significance remains determined.
Sotaro Oshida, MD, Yosuke Akamatsu, MD, Yoshiyasu Matsumoto, MD, Shinya Ishigame, MD, Yasushi Ogasawara, MD, Kenta Aso, MD, Hiroshi Kashimura, MD   +6 more
doaj   +1 more source