Results 91 to 100 of about 7,125 (253)

Hypoxemia During Extreme Hyperleukocytosis: How Spurious? [PDF]

Respiratory Care, 2015
Spurious hypoxemia has been described in case reports during extreme hyperleukocytosis and has led to recommendations for immediate cooling and analysis of arterial blood gases (ABGs). We sought to determine, in samples processed as recommended, the magnitude of spurious hypoxemia in acute leukemia subjects with hyperleukocytosis.A retrospective chart ...
Andry, Van de Louw, Ruchi J, Desai, Coursen W, Schneider, David F, Claxton   +3 more
openaire   +2 more sources

Chronic Myeloid Leukemia Presenting With T‐Lymphoid Blast Crisis in a Young Female With Marked Hyperleukocytosis: A Case Report

eJHaem, Volume 7, Issue 2, April 2026.
Abstract Background Chronic myeloid leukemia (CML) presenting in blast crisis (BC) is uncommon in the era of tyrosine kinase inhibitor (TKI) treatment, and T‐lymphoblastic BC is exceptionally rare. We report a case of T‐lymphoid BC presenting with extreme hyperleukocytosis.
E. Somasundaram, R. P. Hasserjian, B. J. Aubrey, A. T. Fathi, H. Hock   +4 more
wiley   +1 more source

A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia [PDF]

, 2018
MYC-translocated T-lineage acute lymphoblastic leukemia (T-ALL) is a rare subgroup of T-ALL associated with CDKN2A/B deletions, PTEN inactivation, and absence of NOTCH1 or FBXW7 mutations.
Amadori, Alberto, Bongiovanni, Deborah, Buldini, Barbara, Macri, Nadia, Martines, Annalisa, Matthijssens, Filip, Milani, Gloria, Minuzzo, Sonia, Piovan, Erich, Schumacher, Richard Fabian, Tosello, Valeria, Van Loocke, Wouder, Van Vlierberghe, Pieter   +12 more
core   +2 more sources

Leukapheresis in Pediatric Acute Leukemia with Hyperleukocytosis: A Single Center Experience

Iranian Journal of Pediatrics
Background: Hyperleukocytosis (HL) in pediatric acute leukemia is associated with increased morbidity and mortality. The indications for leukapheresis (LPH) in these patients remain unclear, and the use of LPH remains controversial.
Özlem Terzi, Ali Aycicek, Ezgi Paslı Uysalol, Saide Erturk, Ozgu Hancerli, Huseyin Avni Solgun, Halil Ibrahim Simsek, Osman Gokturk, Mehmet Selim Ekinci, Cengiz Bayram   +9 more
semanticscholar   +1 more source

Azacitidine-Induced Pneumonitis in a Patient With Acute Myeloid Leukemia and Hyperleukocytosis

Cureus, 2022
Chemotherapy-related toxicity is a complex aspect of oncologic care. Pulmonary toxicity, in particular, poses a significant challenge, as it can have diverse presentations and can closely mimic other common complications of cancer treatment, such as ...
R. Litvin, M. Dasgupta, Mohamed Saad Eldin, Mihir B Shah, S. Fakhran   +4 more
semanticscholar   +1 more source

Pegfilgrastim-induced leukocytosis and hyperleukocytosis

Case Reports in Internal Medicine, 2021
Objective: To report a case of leukocytosis (LCT) and hyperleukocytosis (HLCT) episodes post Pegfilgrastim (Neulasta) administration.Case Summary: A 74-year-old female presented with several episodes of LCT and HLCT following administration of Pegfilgrastim while undergoing adjunct dose dependent chemotherapy for adenocarcinoma of the gallbladder.
Aditi Singh, Morgan M Bailey, Neha J Patel, Danae Hamouda   +3 more
openaire   +2 more sources

Congenital acute myeloid leukemia with unique translocation t(11;19)(q23;p13.3) [PDF]

, 2015
Congenital leukemia is rarely encountered in clinical practice, even in tertiary children's hospitals. Leukemia may cause significant coagulopathy, putting the patient at risk of intracranial hemorrhage.
Bandt, S. Kathleen, Frater, John L, Hurth, Kyle, Kulkarni, Shashikant, Leonard, Jeffrey R, Rao, Rakesh, Wambach, Jennifer A, White, Francis V, Yarbrough, Chester K   +8 more
core   +3 more sources

Chronic myeloid leukaemia presenting as priapism: A report of 2 cases and review of literature

International Journal of Medicine and Health Development, 2010
Introduction: Chronic myeloid leukaemia (CML) patients with hyperleukocytosis may demonstrate signs or symptoms of leukostasis including priapism. Methods: We report two patients with CML who presented with priapism.
S Ocheni, O G Ibegbulam, D B Olusina, A A Oyekunle, M A Durosinmi   +4 more
doaj   +1 more source

LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome [PDF]

, 2011
BACKGROUND: LMO2 is highly expressed at the most immature stages of lymphopoiesis. In T-lymphocytes, aberrant LMO2 expression beyond those stages leads to T-cell acute lymphoblastic leukemia, while in B cells LMO2 is also expressed in germinal center ...
Agirre-Ena, X. (Xabier), Altobelli, G.G. (Giovanna G.), Aznar, M.A. (María Ángela), Bobadilla, M. (Míriam), Calasanz-Abinzano, M.J. (Maria Jose), Fresquet, V. (Vicente), Lossos, I.S. (Izidore S.), Malumbres, R. (Raquel), Martin-Palanco, V. (Vanesa), Martinez-Climent, J.A. (José Ángel), Prosper, F. (Felipe), Robles, E.F. (Eloy Francisco), Roman-Gomez, J. (José), Smeland, E.B. (Erlend B.)   +13 more
core  

Lemierre's syndrome and genetic polymorphisms: a case report. [PDF]

, 2006
BACKGROUND: Lemierre's syndrome presents a classic clinical picture, the pathophysiology of which remains obscure. Attempts have been made to trace genetic predispositions that modify the host detection of pathogen or the resultant systemic reaction ...
Jean-Michel Constantin, Jean-Paul Mira, Renaud Guerin, Sophie Cayot-Constantin, Olivier Lesens, Florence Gourdon, Jean-Pierre Romaszko, Philippe Linval, Henri Laurichesse, Jean-Etienne Bazin, A Lemierre, LH Hagelskjaer, DM Citron, ZL Tan, M Desvaux, TR Hawn, T Schmid, G Balta, J Texereau, R Segui, RG Westendorp, T Menges, E Haralambous, I Ott   +23 more
core   +4 more sources