Results 1 to 10 of about 4,419 (217)

Hyperleukocytosis and Leukostasis in Acute Myeloid Leukemia: Can a Better Understanding of the Underlying Molecular Pathophysiology Lead to Novel Treatments?

open access: yesCells, 2020
Up to 18% of patients with acute myeloid leukemia (AML) present with a white blood cell (WBC) count of greater than 100,000/µL, a condition that is frequently referred to as hyperleukocytosis.
Jan Philipp Bewersdorf, Amer M Zeidan
exaly   +3 more sources

Effects of Diabetes on Microcirculation and Leukostasis in Retinal and Non-Ocular Tissues: Implications for Diabetic Retinopathy

open access: yesBiomolecules, 2020
Changes in retinal microcirculation are associated with the development of diabetic retinopathy (DR). However, it is unclear whether such changes also develop in capillary beds of other non-retinal tissues.
Ana Santos Silva-Herdade   +2 more
exaly   +3 more sources

Bowel, lung, and retinal ischemia: Rare manifestations of leukostasis syndrome in a man with chronic lymphocytic leukemia—A case report and review of the literature

open access: yesCurrent Problems in Cancer: Case Reports, 2023
Leukapheresis is a resource-intensive and high-risk treatment with unclear benefits when used for leukostasis syndrome in hematologic malignancies.
Bowen He   +3 more
doaj   +1 more source

The role of therapeutic leukapheresis in hyperleukocytotic AML. [PDF]

open access: yesPLoS ONE, 2014
Hyperleukocytosis in AML with leukostasis is a serious life-threatening condition leading to a high early mortality which requires immediate cytoreductive therapy. Therapeutic leukapheresis is currently recommended by the American Society of Apheresis in
Friederike Pastore   +4 more
doaj   +1 more source

Intracranial Hemorrhage in a Pediatric Patient with Chronic Myeloid Leukemia in Chronic Phase: A Case Report

open access: yesCase Reports in Oncology, 2021
Chronic myeloid leukemia (CML) is an uncommon entity in pediatric patients. CML in chronic phase (CML-CP) has a relatively favorable outcome. Leukostasis occurs in 9.7% of patients with CML.
Nobuhisa Takahashi   +5 more
doaj   +1 more source

LEUKAPHERESIS AS A TEMPORIZING MEASURE IN LEUKOSTASIS DUE TO ACUTE MYELOID LEUKEMIA

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introduction: Leukapheresis is a procedure based on mechanical separation of leukocytes and it has been used in many hematological disorders such as Acute Myeloid Leukemia (AML).
ACP Silva   +9 more
doaj   +1 more source

Leukostasis by hyperleukocytic childhood acute leukemia: pathophysiology, clinical presentation, and emergency care [PDF]

open access: yesPediatric Emergency Medicine Journal, 2019
Hyperleukocytosis (HL), defined by a peripheral white blood cell (WBC) count exceeding 100,000/mm3, is occasionally observed in childhood acute leukemia.
Ki Lyong Nam   +2 more
doaj   +1 more source

Leukostasis in an Adult with AML Presenting as Multiple High Attenuation Brain Masses on CT [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Acute myeloid leukemia (AML) is a hematologic malignancy that can present with central nervous system (CNS) symptoms. Neurological symptoms may result from the local accumulation of malignant cells in or near the brain (chloroma), infection, hemorrhage,
Abdulaziz Ahmad AlGharras   +3 more
doaj   +1 more source

Hyperleukocytosis (Re)Visited- Is it always Leukaemia: A Report of Two Cases and Review of Literature [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Hyperleukocytosis is defined as total leukocyte count of more than 100×109 /L. Commonly seen in leukaemic conditions, nonleukaemic causes are usually not encountered and thought of. We report two such non-malignant cases of hyperleukocytosis.
Ashutosh Rath, Richa Gupta
doaj   +1 more source

The value of leukapheresis for treatment of priapism as presenting feature of chronic myeloid leukemia—Case report and review of literature

open access: yeseJHaem, 2022
Priapism is a rare presenting feature of chronic myeloid leukemia (CML) in male patients. Treatment aims to relieve symptoms and to prevent erectile dysfunction. Several treatment modalities exist, however no standard treatment is recommended.
Marleen G. A. M. van derVelde   +3 more
doaj   +1 more source

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