Twenty Years of Therapeutic Leukocytapheresis in Newly Diagnosed Acute Myeloid Leukemia: Insights From A Single Center. [PDF]
J Clin ApherABSTRACT Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy, and 5%–20% of newly diagnosed patients present with hyperleukocytosis (HL). HL, most often defined as WBC > 100 000/μL, is a hematologic emergency associated with severe complications, early mortality, and poor prognosis, requiring immediate intervention.
Latal V +10 more
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Advanced Lymphoblastic Lymphoma, NOS in Leukaemic Phase Presenting With Sudden and Fatal CNS Haemorrhage. [PDF]
Case Rep PatholB/T‐lymphoblastic lymphoma (LBL), not otherwise specified (NOS), is a rare precursor lymphoid neoplasm that exists along a biological spectrum with acute lymphoblastic leukaemia (ALL). Although traditionally distinguished by the extent of bone marrow involvement, this separation becomes increasingly blurred in advanced or leukaemic presentations ...
Antiri EK, Gyasi RK, Ulzen-Appiah K.
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Leukapheresis in Pediatric T-ALL with Extreme Hyperleukocytosis: A Case Highlighting the Importance of Early Recognition [PDF]
Journal of Investigative Medicine High Impact Case ReportsHyperleukocytosis (HL) in acute leukemia is associated with increased morbidity and mortality, mainly secondary to the effects of leukostasis. Many strategies for cytoreduction exist, however prompt initiation of chemotherapy is paramount.
Allison Guild DO +4 more
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Emergence of Recombinant Myxoma Virus in Algerian Farmed Rabbits: Molecular and Phylogenetic Evidence. [PDF]
Transbound Emerg DisMyxomatosis is a severe viral disease of lagomorphs that has recently seen the emergence of a recombinant myxoma virus (MYXV). Data from Africa remain scarce. Here we report the first confirmed detection and genomic characterization of a recombinant MYXV in Algeria.
Maziz-Bettahar S +6 more
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Pulmonary leukostasis as a complication of leukemia
Southwest Respiratory and Critical Care Chronicles, 2015 Multiple acute pulmonary complications occur in patients with hematologic malignancies. They might be associated with the disease itself, with complications from treatment, or with the consequences of an impaired immune status.
Pantaree Aswanetmanee +2 more
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A young adult patient with Philadelphia positive acute lymphoblastic leukemia presenting with extreme hyperleukocytosis [PDF]
Clinical Case ReportsKey Clinical Message Extreme hyperleukocytosis (Leukocyte count >200 × 109/L) in an adolescent young adult (AYA) patient with B‐ALL could result in mild symptoms of leukostasis.
Gulten Tikit +4 more
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Unilateral sudden hearing loss as the first presenting symptom of chronic myeloid leukemia: a case report and literature review [PDF]
Frontiers in OncologyChronic myeloid leukemia (CML) with sudden deafness as the first symptom is clinically rare and easily overlooked. No conventional treatment for CML-associated sudden hearing loss exists and hearing outcomes remain poor. Here, we describe a case in which
Le Sun +4 more
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Priapismus as Leukostasis Manifestation in Chronic Myeloid Leukemia
Acta Medica Indonesiana, 2020 Chronic Myeloid Leukemia (CML) is a myeloproliferative disease characterized by the presence of Philadelphia chromosome or BCR-ABL oncogene fusion. Patients with CML commonly present in the chronic phase with chief complaint of abdominal pain or early ...
Wulyo Rajabto +3 more
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A Hyperacute Presentation of Small Cell, Non-Nodal Mantle Cell Lymphoma [PDF]
Case Reports in HematologyMantle cell lymphoma (MCL) is an aggressive mature B-cell non-Hodgkin lymphoma. Patients often present with lymphadenopathy, early satiety, and B-symptoms. Presentation with hyperleukocytosis is rare.
Jodi Chiu, Mark Crowther
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