Results 61 to 70 of about 7,125 (253)

Hyperleukocytosis in a neuroblastoma patient after treatment with natural killer T cells expressing a GD2-specific chimeric antigen receptor and IL-15

Journal for ImmunoTherapy of Cancer
The ability of immune cells to expand numerically after infusion distinguishes adoptive immunotherapies from traditional drugs, providing unique therapeutic advantages as well as the potential for unmanageable toxicities.
Gengwen Tian, Amy N. Courtney, Hangjin Yu, S. Bhar, Xin Xu, Gabriel A Barragán, Claudia Martinez Amador, Nisha Ghatwai, Michael S Wood, Deborah Schady, A. Montalbano, Shantan Reddy, A. Roche, David A. de la Cerda, Donald Williams Parsons, Erica J Di Pierro, Frederic D. Bushman, A. Heczey, L. Metelitsa   +18 more
semanticscholar   +1 more source

GScluster: Network-weighted gene-set clustering analysis [PDF]

, 2019
Background: Gene-set analysis (GSA) has been commonly used to identify significantly altered pathways or functions from omics data. However, GSA often yields a long list of gene-sets, necessitating efficient post-processing for improved interpretation ...
Baik, Bukyung, Chi, Sang-Mun, Kim, Jinhwan, Kim, Seon-Kyu, Kim, Seon-Young, Nam, Dougu, Yoon, Sora   +6 more
core   +1 more source

Haploidentical, unmanipulated,G-CSF primed bona marrow transplantation for patients with high risk hematological malignancies [PDF]

, 2013
Eighty patients with high-risk hematologic malignancies underwent unmanipulated, G-CSF–primed BM transplantation from an haploidentical family donor. Patients were transplanted in first or second complete remission (CR, standard-risk: n =45) or in > ...
Adorno, G, Andreani, M, Angelini, S, Arcese, W, Bavaro, P, Cerretti, R, Cudillo, L, De Angelis, G, De Felice, L, Di Bartolomeo, P, Di Nicola, M, Montanari, M, Nagler, A, Papalinetti, G, Papola, F, Picardi, A, Rapanotti, M, Santarone, S, Sarmati, L   +18 more
core   +1 more source

Hyperleukocytosis Does Not Present a Worse Prognosis in Acute Myeloid Leukemia (Non-APL) with Favorable Risk According to ELN-2022 Criteria: A Retrospective Study

Blood, 2023
Introduction: Acute myeloid leukemia (AML) with hyperleukocytosis, characterized by a white blood cell count ≥100,000/µL, is usually considered a subtype associated with poor prognosis. For AML patients with hyperleukocytosis, more aggressive treatment
Shuyue Bao, Jinya Lin, Yuan-yuan Zhu, Weijia Huang, Wei-yan Zheng, G. Wei, Z. Cai, Yi Luo, Yi Zhao, Jimin Shi, He Huang, Jie Sun   +11 more
semanticscholar   +1 more source

SPECIFIC HYPERLEUKOCYTOSIS [PDF]

Archives of Internal Medicine, 1914
We have already briefly described the specific and extreme grade of hyperleukocytosis that follows the intravenous injection of living typhoid bacilli in rabbits that have been immunized against this microorganism.1In the present communication we wish to consider more fully the detail and mechanism of this phenomenon and its analog in other types of ...
openaire   +1 more source

Squamous cell carcinoma associated with Xeroderma pigmentosum: an unusual presentation with a tremendously huge mass over the face and paraneoplastic hypercalcemia-hyperleukocytosis

The Turkish Journal of Pediatrics, 2017
Xeroderma pigmentosum (XP) is a rare autosomal recessive disorder that results from genetic defects in DNA repair and manifests with a marked hypersensivity to ultraviolet rays. Children with X-P are at high risk of developing skin cancers. On the other
Suna Emir, Şadan Hacısalihoğlu, Derya Özyörük, Dilek Kaçar, Arzu Erdem, Esra Karakuş   +5 more
doaj   +1 more source

KLK2 single-nucleotide polymorphism rs198977 is associated with increased susceptibility and hyperleukocytosis in AML

Frontiers in Genetics, 2023
Introduction: Acute myeloid leukemia (AML) is a heterogeneous myeloid malignancy with abnormal molecular diversity. Tissue kallikrein 2 (KLK2) is a kind of serine protease, and has a close relationship with the occurrence and development of malignant ...
Guangqiang Meng, Peng Li, Mingying Li, Yuyan Wu, Yuechan Ma, Tao Sun, Tao Sun, Chunyan Ji   +7 more
doaj   +1 more source

Risk factors of acute kidney injury in pediatric acute lymphoblastic leukemia with hyperleukocytosis ymphoblastic Leukemia

Paediatrica Indonesiana, 2023
Background Acute kidney injury (AKI) can be found in pediatric acute lymphoblastic leukemia (ALL) patients with hyperleukocytosis. Acute kidney Injury (AKI) increases hospital length of stay and mortality.
Rengganis Ayu Kinanti, R. Palupi-Baroto, S. Sutaryo   +2 more
semanticscholar   +1 more source

MLL-MLLT10 fusion in acute monoblastic leukemia: variant complex rearrangements and 11q proximal breakpoint heterogeneity [PDF]

, 2004
Cytogenetic studies of acute monoblastic leukemia cases presenting MLL-MLLT10 (alias MLL-AF10) fusion show a broad heterogeneity of chromosomal breakpoints.
DI CATALDO A, LANINO E, LO NIGRO L, MASERATI E, MORERIO C, PANARELLO C, PASQUALI F., RAPELLA A, ROSANDA C   +8 more
core   +1 more source

Facial nerve paralysis in acute otomastoiditis as presenting symptom of FAB M2, T8;21 leukemic relapse. Case report and review of the literature [PDF]

, 1996
Granulocytic sarcoma (chloroma) is a rare solid, extramedullary tumour composed of immature granulocytes, occurring during granulocytic leukemia. Leukemic involvement of the temporal bone is not uncommon and may present in a variety of ways.
A. DI MARIO, G. ALMADORI, G. CADONI, M. DEL NINNO, OTTAVIANI F   +4 more
core   +1 more source