Results 41 to 50 of about 194,902 (312)

Effect of atorvastatin on plasma apoE metabolism in patients with combined hyperlipidemia

open access: yesJournal of Lipid Research, 2002
Atorvastatin, a synthetic HMG-CoA reductase inhibitor used for the treatment of hyperlipidemia and the prevention of coronary artery disease, significantly lowers plasma cholesterol and low-density lipoprotein cholesterol (LDL-C) levels.
Jeffrey S. Cohn   +11 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Hyperlipidemia and male infertility [PDF]

open access: yes, 2021
Hyperlipidemia is a common disease affecting 25% of adults in developed nations. Approximately 50% of the middle-aged adult population have been reported to have total cholesterol level above the normal range. Worldwide, the incidence of dyslipidaemia is
Hamad Alfarisi, Hamad Abdulsalam   +1 more
core   +1 more source

Interaction of Intraprocedural Antiplatelets and Intravenous Thrombolysis in Acute Intracranial Stenting: RESISTANT Registry Subanalysis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes   +75 more
wiley   +1 more source

Hyperlipidemia and mortality associated with diabetes mellitus co-existence in Chinese peritoneal dialysis patients

open access: yesLipids in Health and Disease, 2020
Background To evaluate associations between diabetes mellitus (DM) coexisting with hyperlipidemia and mortality in peritoneal dialysis (PD) patients. Methods This was a retrospective cohort study with 2939 incident PD patients in China from January 2005 ...
Xin Wei   +7 more
doaj   +1 more source

New advances in the hyperlipidemia treatment

open access: yes, 2021
Current therapies of cardiovascular diseases have potency in reducing the risks. However, there are limitations and residual risks that remain. Non-adherence, drug resistance and side effects much often hinder the treatments that the optimal lipid level ...
YoungRyun, Mo
core  

Attenuates Hyperglycemia, Hyperlipidemia, and Oxidative Stress in Diabetic Rats

open access: yes, 2020
This study investigates the effect of fatty acid and sterol rich extract from the stem back of S. roxburghii (MESS) on hyperglycemia, hyperlipidemia, and oxidative stress induced by high fat diet/streptozotocin (HFD/STZ) in rats.
Makinde, Emmanuel Ayobami   +7 more
core   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon   +9 more
wiley   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Association between serum Klotho concentration and hyperlipidemia in adults: a cross-sectional study from NHANES 2007–2016

open access: yesFrontiers in Endocrinology, 2023
ObjectiveThe Klotho protein is a well-documented anti-aging protein known for its diverse biological functions. Hyperlipidemia is an established independent risk factor for various chronic diseases.
Shaohua Yan   +4 more
doaj   +1 more source

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