Results 171 to 180 of about 194,902 (312)

Amorphous Solid Dispersions for BCS Class II Antihyperlipidemic Drugs: From Drug-Polymer Interactions to in vivo Performance. [PDF]

Drug Des Devel Ther
Ridwan S, Pratiwi R, Hildayani SZ, Budiman A.   +3 more
europepmc   +1 more source

Challenging the Leukocyte‐Centric Model of Innate Immunity: The Emerging Role of Structural Cells in Immune Defense

iNew Medicine, EarlyView.
Structural cells (endothelial, epithelial, neural, and muscle) actively participate in innate immunity as primary responders, challenging the traditional leukocyte‐centric paradigm and opening new therapeutic avenues for precision medicine. ABSTRACT Innate immunity has long been viewed as the domain of circulating mobile immune cells orchestrating ...
Sofya Urvanova, Suowen Xu
wiley   +1 more source

Association of Maternal Hyperlipidemia Combined with Gestational Diabetes Mellitus with Adverse Maternal and Neonatal Outcomes: A Retrospective Cohort Study. [PDF]

Int J Womens Health
Wang J, Chen M, Wu H, Zhou M, Chen D, Gao Y.   +5 more
europepmc   +1 more source

Drugs for the Treatment of Hyperlipidemia

, 2001
Hyperlipidemia is a major risk factor for the development of cardiovascular disease. Considerable evidence suggests that drugs with the ability to lower low density lipoprotein-cholesterol also lower cardiovascular deaths.
Stone, William L., Chin, T K.
core  

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Resveratrol Ameliorated Hyperlipidemia: Association with Modulation of the Gut Microbiota and Bile Acid Metabolism. [PDF]

Nutrients
Luo R, Peng Q, Wu S, Liu S, Wang C.
europepmc   +1 more source

Multimodal Comparison of Left Ventricular Function and Volume Assessment Methods in Patients With Coronary Artery Disease: Echocardiography, Nuclear Myocardial Perfusion Imaging, and Cardiac Magnetic Resonance

iRADIOLOGY, EarlyView.
Nitrogen‐13 ammonia, positron emission tomography myocardial perfusion imaging shows excellent correlation and agreement with cardiac magnetic resonance (CMR) in the assessment of left ventricular function and volumes in patients with coronary artery disease. It offers a reliable alternative when CMR is contraindicated.
Fanghu Wang, Xiaochun Zhang, Entao Liu, Xinchao Yao, Zeyin Xiang, Hui Yuan, Lei Jiang   +6 more
wiley   +1 more source

Recent Advances in the Antihyperlipidemic Activity of Marine Polysaccharides. [PDF]

Mar Drugs
Liu Y, Liu H, Li D, Ma S, Li C.
europepmc   +1 more source

Establishment and Application of a Quantitative Lipemia Index as a Novel Indicator for Assessing Lipemic Interference in Clinical Chemistry

Journal of Clinical Laboratory Analysis, EarlyView.
A rigorously validated quantitative lipemia index (LI) assay was established for direct serum turbidity measurement. This standardized LI metric demonstrated significantly stronger correlation with lipemic interference (rs = 0.822) than conventional triglyceride concentration (rs = 0.770), consistent with its direct measurement of optical turbidity ...
Haifeng Xie, Shuhua Bao, Pengcheng Tong, Peng Li, Zhe Shen, Jinlong Wei   +5 more
wiley   +1 more source

Identification of Hypolipidemic Constituents from <i>Microctis folium</i> Using an Integrated Strategy of Chemical Profiling, Pharmacokinetics, Network Pharmacology and Experimental Validation. [PDF]

Pharmaceuticals (Basel)
Zeng Z, Liu Y, Bi X, Chen W, Ouyang Y, Zhang J, Chen W, Xiao G.   +7 more
europepmc   +1 more source