Introduction Type 2 diabetes mellitus (T2DM) is among the world's top 10 leading causes of death. Additionally, prediabetes is a major risk factor for diabetes.
Negar Dinarvand +5 more
doaj +1 more source
Plasma kinetics of VLDL and HDL apoC-I in normolipidemic and hypertriglyceridemic subjects
ApoC-I has several different lipid-regulating functions including, inhibition of receptor-mediated uptake of plasma triglyceride-rich lipoproteins, inhibition of cholesteryl ester transfer activity, and mediation of tissue fatty acid uptake. Since little
Jeffrey S. Cohn +8 more
doaj +1 more source
Comparison of the anti-inflammatory and antilipidemic activity of diosmin and saroglitazar in a model of nonalcoholic fatty liver induced by a high-fat diet in Wistar rats [PDF]
Objective(s): Non-alcoholic fatty liver disease (NAFLD) is the most common liver-related metabolic disorder in the world, with a global prevalence of 25%.
Reza Afarin +6 more
doaj +1 more source
Background This cohort study was conducted to examine the association between modifiable risk factors, including hypertension, smoking, physical activity, diabetes, cholesterol, and high-density lipoprotein with Framingham risk score in the prediction of
Nader Saki +8 more
doaj +1 more source
In vitro factors affecting the concentration of gamma-LpE (γ-LpE) in human plasma
Gamma-LpE (γ-LpE), a sphingomyelin-rich lipoprotein that contains apolipoprotein (apo) E as its only protein component, has been proposed to play a role in cellular cholesterol efflux by acting, like pre-β1-LpA-I, as an initial acceptor of cell-derived ...
Larbi Krimbou +4 more
doaj +1 more source
Previous studies have investigated the potential atherogenicity and thrombogenicity of triglyceride-rich lipoprotein (TRL) remnants by isolating them from plasma within a remnant-like particle (RLP) fraction, using an immunoaffinity gel containing ...
Caroline Marcoux +4 more
doaj +1 more source
Association of apolipoprotein E with α2-macroglobulin in human plasma
Apolipoprotein (apo) E plays a central role in the transport of lipids among different organs and cell types, whereas α2-macroglobulin (α2M) is responsible for the binding and inactivation of plasma proteases, as well as the transport of various ...
Larbi Krimbou +3 more
doaj +1 more source
Characterization of Common β-Thalassemia Major Mutations in Southwest Iran with Respect to Biochemical Parameters, Oxidative Status and Complications [PDF]
Background & Objective: Beta-thalassemia are among the most common autosomal recessive genetic disorders in Iran, especially in Khuzestan province. Beta-thalassemia exhibits significant phenotype heterogeneity and there are currently more than 200 known ...
Hamid Yaghooti +3 more
doaj
Curcumin and saroglitazar attenuate diet-induced nonalcoholic steatohepatitis by activating the Nrf2 pathway and suppressing ERK1/2 signaling [PDF]
Objective(s): Non-alcoholic fatty liver disease (NAFLD) is a chronic steatohepatitis disorder. If left untreated, it can progress to hepatocellular carcinoma.
Reza Afarin +6 more
doaj +1 more source
Up-regulated microRNA-185-3p inhibits the development of hyperlipidemia in rats
Introduction: MicroRNA (miR)-185-3p functions in multiple cancers, while the underlying function of miR-185-3p in hyperlipidemia remained obscure. This research was conducted to unravel its function in hyperlipidemia development via modulating mastermind-
Hua Zhao, Yanbing Li
doaj +1 more source

