Results 41 to 50 of about 194,043 (314)

A new method for measurement of total plasma PCSK9: clinical applications

Journal of Lipid Research, 2010
The proprotein convertase subtilisin kexin-9 (PCSK9) circulates in plasma as mature and furin-cleaved forms. A polyclonal antibody against human PCSK9 was used to develop an ELISA that measures total plasma PCSK9 rather than only the mature form. A cross-
Geneviève Dubuc, Michel Tremblay, Guillaume Paré, Hélène Jacques, Josée Hamelin, Suzanne Benjannet, Lucie Boulet, Jacques Genest, Lise Bernier, Nabil G. Seidah, Jean Davignon   +10 more
doaj   +1 more source

Hypolipidemic effects of chitosan and its derivatives in hyperlipidemic rats induced by a high-fat diet

Food & Nutrition Research, 2016
Background: Hyperlipidemia (HLP) is the primary risk factor of cardiovascular disease (CVD). Various factors, including genetics, physical inactivity, and daily nutritional habits, affect the prevalence of HLP.
Haitao Pan, Qingyun Yang, Guidong Huang, Chen Ding, Peiqiu Cao, Lanlan Huang, Tiancun Xiao, Jiao Guo, Zhengquan Su   +8 more
doaj   +1 more source

Anti-Obese Effect of Glucosamine and Chitosan Oligosaccharide in High-Fat Diet-Induced Obese Rats

Marine Drugs, 2015
Objective: This study is to evaluate the anti-obese effects of glucosamine (GLC) and chitosan oligosaccharide (COS) on high-fat diet-induced obese rats. Methods: The rats were randomly divided into twelve groups: a normal diet group (NF), a high-fat diet
Lanlan Huang, Jian Chen, Peiqiu Cao, Haitao Pan, Chen Ding, Tiancun Xiao, Pengfei Zhang, Jiao Guo, Zhengquan Su   +8 more
doaj   +1 more source

Impact of Gut Microbiota and Microbiota-Related Metabolites on Hyperlipidemia

Frontiers in Cellular and Infection Microbiology, 2021
Hyperlipidemia, defined as the presence of excess fat or lipids in the blood, has been considered as a high-risk factor and key indicator of many metabolic diseases.
Xiaokang Jia, Xiaokang Jia, Xiaokang Jia, Wen Xu, Wen Xu, Lei Zhang, Xiaoyan Li, Xiaoyan Li, Ruirui Wang, Shuisheng Wu, Shuisheng Wu   +10 more
doaj   +1 more source

Remnant-like particle cholesterol and triglyceride levels of hypertriglyceridemic patients in the fed and fasted state

Journal of Lipid Research, 2000
Potentially atherogenic triglyceride-rich lipoprotein (TRL) remnants can be isolated and quantitated as remnant-like particles (RLP), using an immunoaffinity gel containing specific anti-human apolipoprotein A-I (apoA-I) and apoB-100 monoclonal ...
Caroline Marcoux, Paul N. Hopkins, Tao Wang, Elizabeth Teng Leary, Katsuyuki Nakajima, Jean Davignon, Jeffrey S. Cohn   +6 more
doaj   +1 more source

A cross-sectional study exploring the relationship between the dietary inflammatory index and hyperlipidemia based on the National Health and Nutrition Examination Survey (2005–2018)

Lipids in Health and Disease, 2023
Background Hyperlipidemia is closely associated with dietary patterns and inflammation. However, the relationship between hyperlipidemia and the inflammatory potential of diets remains unexplored.
Yu Han, Xijuan Jiang, Yabin Qin, Yile Zhao, Guying Zhang, Chao Liu   +5 more
doaj   +1 more source

Elevation of serum E-selectin in Thai hyperlipidemia adults [PDF]

, 2021
Background: Hyperlipidemia is an important risk factor of cardiovascular diseases (CVD), whose pathogenesis involves vascular endothelial dysfunction.
Kongkhum, Sudawadee, Michuea, Apinya, Fongsupa, Somsak, Rerksngarm, Thaval   +3 more
core   +1 more source

Concept of Hyperlipidemia [PDF]

, 2017
In this modern era, due to varying factors of faulty dietary habits, work pressure, competitive lifestyles, longevity, all contribute to disease Hyperlipidemia, it is a high level of fats in the blood.
Kavita M. B., Divyasree C. H., Kavita MB, Dr. Shivakumar, Divyasree CH, Sreeharsha N., Shivakumar ., Sreeharsha N   +7 more
core   +1 more source

Hyperlipidemia in Patients with Calcific Tendinitis

, 2022
Objective: Calcific tendinitis is a disease of unclear etiology and is associated with metabolic diseases. Hyperlipidemia, one of the metabolic diseases with systemic effects, may be associated with tendinopathy and tendinitis. In this study, we aimed to
Yuce, Elif Ilkay, Inanc, Ibrahim Halil, Ozyer, Fatih, Polat, Esra   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source