Results 31 to 40 of about 166,195 (263)

A new method for measurement of total plasma PCSK9: clinical applications

Journal of Lipid Research, 2010
The proprotein convertase subtilisin kexin-9 (PCSK9) circulates in plasma as mature and furin-cleaved forms. A polyclonal antibody against human PCSK9 was used to develop an ELISA that measures total plasma PCSK9 rather than only the mature form. A cross-
Geneviève Dubuc, Michel Tremblay, Guillaume Paré, Hélène Jacques, Josée Hamelin, Suzanne Benjannet, Lucie Boulet, Jacques Genest, Lise Bernier, Nabil G. Seidah, Jean Davignon   +10 more
doaj   +1 more source

Hypolipidemic effects of chitosan and its derivatives in hyperlipidemic rats induced by a high-fat diet

Food & Nutrition Research, 2016
Background: Hyperlipidemia (HLP) is the primary risk factor of cardiovascular disease (CVD). Various factors, including genetics, physical inactivity, and daily nutritional habits, affect the prevalence of HLP.
Haitao Pan, Qingyun Yang, Guidong Huang, Chen Ding, Peiqiu Cao, Lanlan Huang, Tiancun Xiao, Jiao Guo, Zhengquan Su   +8 more
doaj   +1 more source

Anti-Obese Effect of Glucosamine and Chitosan Oligosaccharide in High-Fat Diet-Induced Obese Rats

Marine Drugs, 2015
Objective: This study is to evaluate the anti-obese effects of glucosamine (GLC) and chitosan oligosaccharide (COS) on high-fat diet-induced obese rats. Methods: The rats were randomly divided into twelve groups: a normal diet group (NF), a high-fat diet
Lanlan Huang, Jian Chen, Peiqiu Cao, Haitao Pan, Chen Ding, Tiancun Xiao, Pengfei Zhang, Jiao Guo, Zhengquan Su   +8 more
doaj   +1 more source

Remnant-like particle cholesterol and triglyceride levels of hypertriglyceridemic patients in the fed and fasted state

Journal of Lipid Research, 2000
Potentially atherogenic triglyceride-rich lipoprotein (TRL) remnants can be isolated and quantitated as remnant-like particles (RLP), using an immunoaffinity gel containing specific anti-human apolipoprotein A-I (apoA-I) and apoB-100 monoclonal ...
Caroline Marcoux, Paul N. Hopkins, Tao Wang, Elizabeth Teng Leary, Katsuyuki Nakajima, Jean Davignon, Jeffrey S. Cohn   +6 more
doaj   +1 more source

A cross-sectional study exploring the relationship between the dietary inflammatory index and hyperlipidemia based on the National Health and Nutrition Examination Survey (2005–2018)

Lipids in Health and Disease, 2023
Background Hyperlipidemia is closely associated with dietary patterns and inflammation. However, the relationship between hyperlipidemia and the inflammatory potential of diets remains unexplored.
Yu Han, Xijuan Jiang, Yabin Qin, Yile Zhao, Guying Zhang, Chao Liu   +5 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Effect of atorvastatin on plasma apoE metabolism in patients with combined hyperlipidemia

Journal of Lipid Research, 2002
Atorvastatin, a synthetic HMG-CoA reductase inhibitor used for the treatment of hyperlipidemia and the prevention of coronary artery disease, significantly lowers plasma cholesterol and low-density lipoprotein cholesterol (LDL-C) levels.
Jeffrey S. Cohn, Michel Tremblay, Rami Batal, Hélène Jacques, Lyne Veilleux, Claudia Rodriguez, P.Hugh R. Barrett, Denise Dubreuil, Madeleine Roy, Lise Bernier, Orval Mamer, Jean Davignon   +11 more
doaj   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Hyperlipidemia and mortality associated with diabetes mellitus co-existence in Chinese peritoneal dialysis patients

Lipids in Health and Disease, 2020
Background To evaluate associations between diabetes mellitus (DM) coexisting with hyperlipidemia and mortality in peritoneal dialysis (PD) patients. Methods This was a retrospective cohort study with 2939 incident PD patients in China from January 2005 ...
Xin Wei, Yueqiang Wen, Qian Zhou, Xiaoran Feng, Fen Fen Peng, Niansong Wang, Xiaoyang Wang, Xianfeng Wu   +7 more
doaj   +1 more source