Results 81 to 90 of about 19,107 (290)

Associations of Overweight, Obesity, and Underweight With High Serum Total Cholesterol Level Over 30 Years Among the Japanese Elderly: NIPPON DATA 80, 90, and 2010

open access: yesJournal of Epidemiology, 2019
Background: The trend of association between overweight and high serum total cholesterol (TC) among the elderly is unclear. In addition, there is little evidence of risk of underweight for high TC.
Yosuke Shibata   +15 more
doaj   +1 more source

Programmable Pentamolecular Cross‐Scale Imaging Reveals the Multiplicative Synergistic Effect of High‐Fat / High‐Salt Diet on Atherosclerosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li   +9 more
wiley   +1 more source

Association between Lipoprotein Lipase Hind III Polymorphism and Serum Levels of Lipids in Semnan City [PDF]

open access: yesJournal of Kerman University of Medical Sciences, 2012
Background & Aims: Lipoprotein lipase (LPL) is one of the key enzymes regulating the metabolism of triglycerides (TG) and HDL cholesterol. The lipoprotein lipase (LPL) gene polymorphisms are possibly involved in the pathophysiology of dyslipidemia.
A.R Bandegi   +2 more
doaj  

Statins: a tale of two pathways—cardiovascular savior, renal ineffectual [PDF]

open access: yesPrecision and Future Medicine
Statins are effective in improving outcomes in the general population. However, in patients with chronic kidney disease (CKD), clinical outcomes and therapeutic approaches require careful interpretation from multiple perspectives.
Jihyun Yang
doaj   +1 more source

Are Statins Anti-Inflammatory? [PDF]

open access: yes, 2012
Large scale clinical trials demonstrate significant reductions in cardiovascular event rates with statin therapy. The observed benefit of statin therapy, however, may be larger in these trials than that expected on the basis of lipid lowering alone ...
Blake, Gavin J., Ridker, Paul M.
core   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

open access: yesAdvanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen   +14 more
wiley   +1 more source

Patient Satisfaction With Medication Pricing in Community Pharmacy Settings: A Cross‐Sectional Study of Individuals With Comorbidities

open access: yesAGING MEDICINE, EarlyView.
The majority of patients in Malaysia purchase medications at community pharmacies for simple medical conditions. One‐fourth of them are not satisfied with the pricing practices at these pharmacies. The majority rely on medical insurance to purchase routine medications.
Amelia Ravindran   +3 more
wiley   +1 more source

Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas [PDF]

open access: yes, 2017
Background Lipid accumulation in the liver and pancreas is primarily caused by combined hyperlipidemia. However, the effect of isolated hypercholesterolemia without hypertriglyceridemia is not fully described.
A Kotronen   +73 more
core   +3 more sources

The intersection of health inequalities and COVID‐19: Evidence from National Health Insurance Big Data in South Korea

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract Health inequalities persist along lines of income and wealth, shaped by unequal access to healthcare, differences in health behaviors, and pre‐existing chronic conditions. The COVID‐19 pandemic further put families in Korea under health strain and worsened their health outcomes.
Jaehyun Nam   +3 more
wiley   +1 more source

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