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Hypertrophy of liver peroxisomes in type II and type IV hyperlipoproteinemia
Atherosclerosis, 1986A morphometric study on liver biopsies from patients with primary hyperlipoproteinemia (IIa n = 4, IIb n = 7, IV n = 7) and in controls (n = 7) was performed by light and electron microscopy. We found hypertrophy of peroxisomes in all subjects with hyperlipoproteinemia.
P Drouin
exaly +3 more sources
The spectrum of type III hyperlipoproteinemia
BACKGROUND: Type III hyperlipoproteinemia is a highly atherogenic dyslipoproteinemia characterized by hypercholesterolemia and hypertriglyceridemia due to markedly increased numbers of cholesterol-enriched chylomicron and very-low-density lipoprotein ...
Jacqueline de Graaf, Allan Sniderman
exaly +2 more sources
Clofibrate in Type II Hyperlipoproteinemia
Acta Medica Scandinavica, 1976ABSTRACT. As part of a double‐blind randomized study, the safety and the lipid‐ and uric acid‐lowering effect of clofibrate have been evaluated in 28 patients with type II hyperlipoproteinemia (HLP). A highly significant reduction of serum cholesterol occurred in type II a and of serum triglyceride and cholesterol in type IIb HLP throughout the 60 ...
J, Ditzel, H O, Bang
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Pseudohomozygous Type II Hyperlipoproteinemia
Dermatologica, 2009Nodular xanthomas on both elbows and a streak-like xanthoma on the intergluteal area developed in a 4-year-old girl with type IIa hyperlipoproteinemia. She had no disease associated with secondary hypercholesterolemia and no family history of hypercholesterolemia. Her xanthomas regressed under fat restriction diet and cholestyramine therapy.
M, Fujita +4 more
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Pseudohomozygous type II hyperlipoproteinemia
The Journal of Pediatrics, 1974Familial hypercholesterolemia (a form of familial type II hyperlipoproteinemia) is transmitted as a dominant trait with homozygotes presenting in childhood with marked elevation of LDL and planar xanthormas. We studied two patients who presented as children with marked elevation of LDL and planar xanthomas but who, after family studies and clinical ...
J, Morganroth +3 more
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Sitosterol in juvenile type II hyperlipoproteinemia
Atherosclerosis, 1978The effect of beta-sitosterol on plasma lipids and lipoproteins was evaluated in a randomized double-blind cross-over trial in 15 children and adolescents with familial hypercholesterolemia over a period of 6 months. Twelve patients completed the study, with good adherence to drug intake.
G, Schlierf +4 more
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Clinics in Endocrinology and Metabolism, 1973
Type II hyperlipoproteinemia is characterized by an abnormally high plasma β-lipoprotein concentration. Hence, an alternative name for the Type II lipoprotein pattern is hyper-β-lipoproteinemia. Although this pattern commonly occurs in the absence of any other lipoprotein abnormality, it may also occur in association with a raised concentration of ...
N B, Myant, J, Slack
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Type II hyperlipoproteinemia is characterized by an abnormally high plasma β-lipoprotein concentration. Hence, an alternative name for the Type II lipoprotein pattern is hyper-β-lipoproteinemia. Although this pattern commonly occurs in the absence of any other lipoprotein abnormality, it may also occur in association with a raised concentration of ...
N B, Myant, J, Slack
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Special Diet for Familial Type II Hyperlipoproteinemia
Archives of Pediatrics & Adolescent Medicine, 1974A suggested diet containing less than 200 mg cholesterol per day, with a polyunsaturate: saturate ratio of 0.9:1 was prepared for young children with familial hypercholesterolemia. A representative meal plan and calculations for a seven-day food intake allow for a practical, economical diet, low in cholesterol and saturated fat, but high in essential ...
R, Larsen, C J, Glueck, R, Tsang
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Treatment of type II hyperlipoproteinemia with d-thyroxine
Atherosclerosis, 1976The effectiveness of a new, almost l-thyroxine free preparation of d-thyroxine (Dynothel) was tested in 15 patients with Type IIa and 4 patients with Type IIb hyperlipoproteinemia. Eleven patients with Type IIa and 3 with Type IIb were responsive to treatment and showed an average 26% decrease in plasma TC. This decrement in plasma TC was mirrored in a
A D, Rakow +4 more
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