Results 71 to 80 of about 7,701 (216)

The intestine and the kidneys : a bad marriage can be hazardous [PDF]

, 2015
The concept that the intestine and chronic kidney disease influence each other, emerged only recently. The problem is multifaceted and bidirectional. On one hand, the composition of the intestinal microbiota impacts uraemic retention solute production ...
Glorieux, Griet, Vanholder, Raymond
core   +1 more source

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism [PDF]

, 2017
In humans, glyoxylate is an intermediary product of metabolism, whose concentration is finely balanced. Mutations in peroxisomal alanine:glyoxylate aminotransferase (hAGT1) cause primary hyperoxaluria type 1 (PH1), which results in glyoxylate ...
Calvo, Ana C., Cellini, Barbara, Mesa-Torres, Noel, Miranda-Vizuete, Antonio, Montioli, Riccardo, Oppici, Elisa, Pey, Ángel L., Salido, Eduardo, Titelbaum, Nicholas   +8 more
core   +1 more source

Computerized tomography‐derived body composition metrics are associated with 24‐h urine lithogenic parameters

BJUI Compass, Volume 7, Issue 1, January 2026.
Abstract Background The relationship between body composition and lithogenic urine parameters remains poorly defined. This study aimed to evaluate associations between computerized tomography (CT)‐derived body composition metrics and 24‐h urine findings. Methods Stone‐forming patients in our Nephrolithiasis Database who underwent 24‐h urine testing and
Reza Lahiji, Lorenzo Storino Ramacciotti, Ernie Morton, Edouard H. Nicaise, Adam Braunschweig, Gregory Palmateer, Benjamin Schmeusser, Dattatraya Patil, Maxwell Richardson, Frank Glover, Ethan Kearns, Aaron Lay, Mohammad Hajiha, Viraj A. Master, Kenneth Ogan   +14 more
wiley   +1 more source

Gut microbiota modulation via fecal microbiota transplantation mitigates hyperoxaluria and calcium oxalate crystal depositions induced by high oxalate diet

Gut Microbes
Hyperoxaluria, including primary and secondary hyperoxaluria, is a disorder characterized by increased urinary oxalate excretion and could lead to recurrent calcium oxalate kidney stones, nephrocalcinosis and eventually end stage renal disease.
Lingyue An, Shujue Li, Zhenglin Chang, Min Lei, Zhican He, Peng Xu, Shike Zhang, Zheng Jiang, Muhammad Sarfaraz Iqbal, Xinyuan Sun, Hongxing Liu, Xiaolu Duan, Wenqi Wu   +12 more
doaj   +1 more source

Microscopic Haematuria [PDF]

, 2005
A 30 year old man is referred for a medical check up before taking a life insurance policy. He is asymptomatic, gives no relevant history, is on no treatment and physical examination is unremarkable. Routine dip-stick analysis of a mid­stream specimen of
Vella, Mario P.
core  

Epidemiology of paediatric renal stone disease: a 22-year single centre experience in the UK [PDF]

, 2017
BACKGROUND: Whilst still rare, the incidence of paediatric stone disease is increasing in developed countries and it is important to evaluate the aetiology.
Bockenhauer, D, Dufek, S, Issler, N, Kleta, R, Smeulders, N, Van't Hoff, W   +5 more
core   +1 more source

Fermentation‐Assisted Valorization: A Sustainable Strategy for Turning Fruit By‐Products Into Value‐Added Food Supplements

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT A substantial proportion of fresh fruit undergoes processing, resulting in underutilized fruit by‑products (FBPs) that are rich in dietary fiber and bioactive compounds. Recent FBP valorization trends demonstrate that fermentation significantly enhances microbiological, nutritional, and sensory attributes, yielding value‑added food supplements.
Abouzar Ghasemi, Salwa Karboune, Denis Groleau, Ismail Fliss   +3 more
wiley   +1 more source

Primary hyperoxaluria type 1 in Tunisian children

Saudi Journal of Kidney Diseases and Transplantation, 2012
To determine the clinical, biological, and radiological futures of primary hyper-oxaluria type 1 in Tunisian children, we retrospectively studied 44 children with primary hyper-oxaluria type 1 who were treated in our center from 1995 to 2009.
Tahar Gargah, Nourchene Khelil, Gharbi Youssef, Wiem Karoui, Mohamed Rachid Lakhoua, Jaouida Abdelmoula   +5 more
doaj   +1 more source

Combined liver-kidney transplant in a 21-month-old child with type 1 primary hyperoxaluria—The perioperative challenges

Indian Journal of Anaesthesia, 2020
Primary hyperoxaluria type 1(PH 1) is the most common indication for a paediatric combined liver-kidney transplant. It is a technically challenging procedure. We describe the challenges in managing a 21-month-old female child weighing 7 kg for a combined
Nidhin Eldo, Sangeeth P Srinivasan, Nisha Rajmohan, Mathew Jacob   +3 more
doaj   +1 more source