Results 101 to 110 of about 97,082 (225)

Phenotypical Characterization of Gastroenterological and Metabolic Manifestations in Patients With Williams–Beuren Syndrome

American Journal of Medical Genetics Part A, Volume 197, Issue 6, June 2025.
ABSTRACT Gastrointestinal (GI) symptoms are common in patients with Williams–Beuren syndrome (WBS), but their prevalence and possible causes are not yet fully known. This study assessed GI symptoms' prevalence and their possible origin by performing a predefined set of tests in adult WBS patients.
Maria Francesca Bedeschi, Annarita Baldassarri, Roberta Villa, Federico Tanzi, Simona Salera, Vincenza Lombardo, Alessandro Draghi, Nicole Piazza O'Sed, Giovanni Casazza, Maurizio Vecchi, Mirella Fraquelli   +10 more
wiley   +1 more source

Beyond Efficacy: Ensuring Safety in Peptide Therapeutics through Immunogenicity Assessment

Journal of Peptide Science, Volume 31, Issue 6, June 2025.
Peptides are increasingly used in diagnosis and treatment due to their selectivity and low side effects. Over 11% of FDA‐approved drugs from 2016 to 2024 were synthetic peptides. However, immunogenicity—an adverse immune response—can limit their safety and efficacy.
Koulla Achilleos, Christos Petrou, Vicky Nicolaidou, Yiannis Sarigiannis   +3 more
wiley   +1 more source

On the functoriality of Lott's secondary analytic index [PDF]

arXiv, 2000
We verify that the formula of X. Ma for the analytic torsion form of an iterated fibration implies that Lott's secondary analytic index is functorial.
arxiv  

Is serum 25‐hydroxyvitamin D deficiency a risk factor for the incidence of slow gait speed in older individuals? Evidence from the English longitudinal study of ageing

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3104-3112, June 2025.
Abstract Aims Cross‐sectional studies demonstrate an association between low serum levels of vitamin D and slower gait speed in older individuals. However, longitudinal studies remain inconclusive. This study investigates whether vitamin D deficiency and insufficiency are risk factors for the incidence of slowness. Materials and Methods A total of 2815
Mariane Marques Luiz, Roberta de Oliveira Máximo, Aline Fernanda de Souza, Thales Batista de Souza, Sara Souza Lima, Leticia Coelho Silveira, Thaís Barros Pereira da Silva, Andrew Steptoe, Cesar de Oliveira, Tiago da Silva Alexandre   +9 more
wiley   +1 more source

Roles of Parathyroid Hormone and Fibroblast Growth Factor 23 in Advanced Chronic Kidney Disease [PDF]

Endocrinology and Metabolism
Parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) each play a central role in the pathogenesis of chronic kidney disease (CKD)-mineral and bone disorder.
Yosuke Nakagawa, Hirotaka Komaba
doaj   +1 more source

Persistent hyperparathyroidism secondary to ectopic parathyroid adenoma in lung: Case report. [PDF]

Front Endocrinol (Lausanne), 2022
Valizadeh M, Ebadinejad A, Amouzegar A, Zakeri A.   +3 more
europepmc   +1 more source

On Reidys and Stadler's metrics for RNA secondary structures [PDF]

arXiv, 2003
We compute explicitly several abstract metrics for RNA secondary structures defined by Reidys and Stadler.
arxiv  

Global, regional and country‐specific burden of chronic kidney disease due to type 1 diabetes mellitus: A systematic analysis of the 2021 global disease burden study

Diabetes, Obesity and Metabolism, Volume 27, Issue 6, Page 3397-3409, June 2025.
Abstract Aims Chronic kidney disease (CKD) affects individual welfare, healthcare systems and societal progress. Of the multifaceted etiological factors, type 1 diabetes mellitus (T1DM) is a prominent contributor to CKD. Materials and Methods We analysed the global incidence, prevalence, deaths and disability‐adjusted life‐years (DALYs) with age ...
Jianran Sun, Wan Hu, Shandong Ye, Min Xu, Datong Deng, Mingwei Chen   +5 more
wiley   +1 more source

Lack of vitamin D signalling per se does not aggravate cardiac functional impairment induced by myocardial infarction in mice.

PLoS ONE, 2018
Epidemiological studies have linked vitamin D deficiency to an increased incidence of myocardial infarction and support a role for vitamin D signalling in the pathophysiology of myocardial infarction.
Kristopher Ford, Nejla Latic, Svetlana Slavic, Ute Zeitz, Marlies Dolezal, Oleh Andrukhov, Reinhold G Erben, Olena Andrukhova   +7 more
doaj   +1 more source

Cost-effectiveness analysis of cinacalcet vs. paricalcitol in the treatment of hyperparathyroidism secondary to chronic kidney disease. [PDF]

J Bras Nefrol, 2023
Ponce D, Cardoso MMA, Rúgolo JRM, Molina SA, Andrade LGM, Curado DDSP.   +5 more
europepmc   +1 more source