Results 101 to 110 of about 55,182 (234)
Beyond Efficacy: Ensuring Safety in Peptide Therapeutics through Immunogenicity Assessment
Peptides are increasingly used in diagnosis and treatment due to their selectivity and low side effects. Over 11% of FDA‐approved drugs from 2016 to 2024 were synthetic peptides. However, immunogenicity—an adverse immune response—can limit their safety and efficacy.
Koulla Achilleos+3 more
wiley +1 more source
Thyrotoxicosis, hyperparathyroidism, and hyperuricaemia. [PDF]
J. K. Nelson, David R. Hadden
openalex +1 more source
Ferric Carboxymaltose (FCM)–Associated Hypophosphatemia (HPP): A Systematic Review
ABSTRACT Background Since 2015, ferric carboxymaltose (FCM), an intravenous (IV) iron formulation used for treating iron deficiency anemia (IDA), has been associated with an increasing number of reported hypophosphatemia (HPP) cases. Information on HPP clinical manifestations and incidence has not been reviewed.
Joseph Magagnoli+4 more
wiley +1 more source
Abstract The third edition of The Bethesda System for Reporting Thyroid Cytopathology includes category IV, follicular neoplasm (FN), which is used to classify fine‐needle aspirates of thyroid nodules that may correspond to invasive follicular‐derived neoplasia other than papillary thyroid carcinoma.
André Lametti+4 more
wiley +1 more source
Primary Hyperparathyroidism, Acute Urinary Infection and Pancreatitis [PDF]
S. Jawaheer
openalex +1 more source
OATP1B, P‐gp, BCRP, and CYP3A are the most contributing drug‐metabolizing enzymes or transporters (DMETs) for commonly prescribed medication. Their activities may change in end‐stage renal disease (ESRD) patients with large inter‐individual variabilities (IIVs), leading to altered substrate drug exposure and ultimately elevated safety risk.
Weijie Kong+15 more
wiley +1 more source
Diagnostic biases are potentially life‐threatening. We present a case of extreme hypercalcemia falsely diagnosed as premature ventricular complexes attributed to heavy coffee consumption, while symptoms and electrocardiographic findings of hypercalcemia were disregarded. Abstract Severe hypercalcemia has an arrhythmogenic effect. We present a case of a
Yuval Avidan, Sameer Kassem
wiley +1 more source