Results 71 to 80 of about 25,820 (298)

Hyperphosphatemia and risks of acute kidney injury, end-stage renal disease, and mortality in hospitalized patients

open access: yesBMC Nephrology, 2019
BackgroundHyperphosphatemia is associated with vascular calcification and bone mineral disorders and is a major concern among patients with chronic kidney disease (CKD).
Hongran Moon   +6 more
semanticscholar   +1 more source

Alkaline phosphatases in the complex chronic kidney disease-mineral and bone disorders [PDF]

open access: yes, 2018
Alkaline phosphatases (APs) remove the phosphate (dephosphorylation) needed in multiple metabolic processes (from many molecules such as proteins, nucleotides, or pyrophosphate). Therefore, APs are important for bone mineralization but paradoxically they
Aguilar, Armando   +8 more
core   +1 more source

Polymeric Anti‐Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution

open access: yesSmall, Volume 21, Issue 21, May 26, 2025.
This study introduces sevelamer (SEV) microparticles as a repurposed adjuvant therapy to combat antimicrobial resistance. SEV microparticles effectively capture vancomycin (VAN) and daptomycin (DAP), preventing these last‐resort antibiotics from driving resistance.
Roya Koshani   +8 more
wiley   +1 more source

The calcilytic agent NPS 2143 rectifies hypocalcemia in a mouse model with an activating calcium-sensing-receptor (CaSR) mutation:relevance to autosomal dominant hypocalcemia type 1 (ADH1) [PDF]

open access: yes, 2015
Autosomal dominant hypocalcemia type 1 (ADH1) is caused by germline gain-of-function mutations of the calcium-sensing receptor (CaSR) and may lead to symptomatic hypocalcemia, inappropriately low serum parathyroid hormone (PTH) concentrations and ...
Allen M. Spiegel   +44 more
core   +1 more source

Fluorinated Zirconium‐Based Metal‐Organic Frameworks as Novel Sorbents to Improve the Efficacy of Hemodialysis Treatment

open access: yesSmall Science, EarlyView.
The incorporation of perfluoroalkyl chains into porous NU‐1000 leads to superior performance in the removal of uremic toxins from samples of CKD patients for two main reasons: improved stability and enhanced removal efficiency of protein‐bound toxins.
Fátima Guerrero   +4 more
wiley   +1 more source

Polymyositis associated with dyspnoea and interstitial lung disease in a dog (Canis familiaris)

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 5‐year‐old, female, spayed coonhound was evaluated for progressive dyspnoea, weakness and weight loss. The patient had increased inspiratory and expiratory respiratory effort and generalised skeletal muscle atrophy. Thoracic radiographs and computed tomography revealed interstitial lung disease. Magnetic resonance imaging revealed multifocal
Kaycee Daentl   +2 more
wiley   +1 more source

Effects of Use of Proton Pump Inhibitors with Calcium Acetate on Serum Phosphorus Levels in Hemodialysis Patients [PDF]

open access: yesCaspian Journal of Internal Medicine, 2023
Background: The increase in serum phosphorus level is an independent risk factor for mortality in patients with chronic renal failure or undergoing dialysis due to end-stage renal disease.
Deniz Çekiç   +2 more
doaj  

Control of hyperphosphatemia beyond phosphate [PDF]

open access: yesKidney International, 2007
Hyperphosphatemia is a prevalent condition in the dialysis population and is associated with bad outcome. Block et al. present data from a post hoc analysis indicating that sevelamer, a noncalcium-containing phosphate binder, may confer a survival benefit in incident hyperphosphatemic hemodialysis patients.
openaire   +3 more sources

Personalized parathyroid hormone therapy for hypoparathyroidism: Insights from pharmacokinetic‐pharmacodynamic modelling

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 1233-1240, April 2025.
Aims A 42‐year‐old male developed chronic primary hypoparathyroidism after total thyroidectomy. Conventional therapy led to recurrent nephrolithiasis and therefore rhPTH(1‐84) (parathyroid hormone [PTH]) treatment was considered. According to the dosing guideline for PTH, calcium plasma levels are adequately controlled with once‐daily administration ...
Maira Visscher   +5 more
wiley   +1 more source

p-Cresyl sulfate [PDF]

open access: yes, 2017
If chronic kidney disease (CKD) is associated with an impairment of kidney function, several uremic solutes are retained. Some of these exert toxic effects, which are called uremic toxins.
Glorieux, Griet   +3 more
core   +3 more sources

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