Results 161 to 170 of about 47,063 (335)
ABSTRACT Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous disorder with limited treatment options in pediatric patients. We report the case of a 9‐year‐old boy with juvenile PRP (type III), who achieved complete disease remission after treatment with secukinumab, an IL‐17A inhibitor, following initial therapeutic resistance to topical ...
Zeno Fratton +2 more
wiley +1 more source
ABSTRACT Peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads (PLACK) syndrome (OMIM616295) is an exceptionally rare autosomal recessive genodermatosis caused by loss‐of‐function pathogenic variants in the CAST gene, encoding calpastatin.
Fiona Haxho +7 more
wiley +1 more source
Reversible generalized cutaneous hyperpigmentation: presenting manifestation of pernicious anemia [PDF]
Filipa Diamantino +3 more
openalex +1 more source
Pigmented Birthmarks and Spinal Neurofibromas in KRAS Mosaicism—Not to Be Confused With NF1
ABSTRACT We report a child presenting with pigmentary skin lesions and spinal neurofibromas who was diagnosed molecularly with KRAS mosaicism. We review the previous literature of two cases of congenital skin lesions and neurofibromas and spinal nerve root hypertrophy caused by KRAS variants and highlight this presentation as an important differential ...
Karina M. Forde +3 more
wiley +1 more source
ABSTRACT Background Early promotion of sun‐protective behavior may play a pivotal role in skin cancer prevention. School‐based interventions have shown effectiveness in increasing sun‐safety knowledge, yet few studies assess children's baseline perceptions before formal education. Objective To assess elementary students' baseline sun‐safety perceptions
Aliyah King, Russell Leong, Reetesh Bose
wiley +1 more source
Hyperpigmentation and chikungunya fever [PDF]
openaire +5 more sources
Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal +3 more
wiley +1 more source
Bleomycin-induced flagellate hyperpigmentation [PDF]
Cristina Resende +3 more
openalex +1 more source
AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer +4 more
wiley +1 more source

