Results 1 to 10 of about 8,134 (194)

PEG minocycline-liposomes ameliorate CNS autoimmune disease. [PDF]

open access: yesPLoS ONE, 2009
Minocycline is an oral tetracycline derivative with good bioavailability in the central nervous system (CNS). Minocycline, a potent inhibitor of matrix metalloproteinase (MMP)-9, attenuates disease activity in experimental autoimmune encephalomyelitis ...
Wei Hu   +9 more
doaj   +2 more sources

Testicular Pain Associated With Minocycline Use [PDF]

open access: yesUrology Case Reports, 2015
Two males ages 16 and 23 years presented with new testicular pain while taking minocycline. Both patients experienced resolution of their symptoms only after minocycline discontinuation. Testicular pain with minocycline use has been previously described,
Victor Kucherov   +2 more
doaj   +2 more sources

Prolonged minocycline treatment impairs motor neuronal survival and glial function in organotypic rat spinal cord cultures. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: Minocycline, a second-generation tetracycline antibiotic, exhibits anti-inflammatory and neuroprotective effects in various experimental models of neurological diseases, such as stroke, Alzheimer's disease, amyotrophic lateral sclerosis and ...
Josephine Pinkernelle   +3 more
doaj   +1 more source

Metformin reverse minocycline to inhibit minocycline-resistant Acinetobacter baumannii by destroy the outer membrane and enhance membrane potential in vitro

open access: yesBMC Microbiology, 2022
Background Acinetobacter baumannii (A. baumannii) is an opportunistic pathogen and has emerged as one of the most troublesome pathogens. Drug resistance in A. baumannii has been reported on a global scale. Minocycline was found to be active against multi-
Tingting Guo   +7 more
doaj   +1 more source

Characterization of the Interactions between Minocycline Hydrochloride and Trypsin with Spectroscopic and Molecular Docking Technology

open access: yesMolecules, 2023
In the current study, the interaction of minocycline hydrochloride (MC) and trypsin (TRP) was studied using fluorescence spectroscopy, synchronous fluorescence spectroscopy, three-dimensional fluorescence spectroscopy, UV-Vis spectroscopy, and molecular ...
Xiaoxia Wang   +6 more
doaj   +1 more source

The blues of minocycline [PDF]

open access: yesQJM, 2011
A 74-year-old female patient with a history of coronary artery disease, hypertension and peripheral vascular disease was admitted with an upper gastrointestinal bleed. She also had a long history of rheumatoid arthritis with the characteristic features of the hands (Figure 1A). She was on minocycline for her rheumatoid arthritis for ∼8 years.
A, Mahta, S, Kesari
openaire   +2 more sources

Prediction of Minocycline Activity in the Gut From a Pig Preclinical Model Using a Pharmacokinetic -Pharmacodynamic Approach

open access: yesFrontiers in Microbiology, 2021
The increase of multidrug-resistant (MDR) bacteria has renewed interest in old antibiotics, such as minocycline, that can be active against various MDR Gram-negative pathogens.
Quentin Vallé   +8 more
doaj   +1 more source

Antimicrobial Effects of Minocycline, Tigecycline, Ciprofloxacin, and Levofloxacin against Elizabethkingia anophelis Using In Vitro Time-Kill Assays and In Vivo Zebrafish Animal Models

open access: yesAntibiotics, 2021
Elizabethkingia anophelis is a multidrug-resistant pathogen. This study evaluated the antimicrobial activity of minocycline, tigecycline, ciprofloxacin, and levofloxacin using in vitro time-kill assays and in vivo zebrafish animal models.
Jiun-Nong Lin   +3 more
doaj   +1 more source

Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review

open access: yesNeural Regeneration Research, 2020
To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and considering the inclusion and exclusion criteria of the study. Studies were included
Yazdan Naderi   +3 more
doaj   +1 more source

Minocycline Treatment Reduces Mass and Force Output From Fast-Twitch Mouse Muscles and Inhibits Myosin Production in C2C12 Myotubes

open access: yesFrontiers in Physiology, 2021
Minocycline, a tetracycline-class of antibiotic, has been tested with mixed effectiveness on neuromuscular disorders such as amyotrophic lateral sclerosis, autoimmune neuritis and muscular dystrophy.
Leonit Kiriaev   +6 more
doaj   +1 more source

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