Results 21 to 30 of about 31,630 (212)

Anti-apoptotic effects of minocycline on doxorubicin-induced cardiotoxicity in male Wistar rats [PDF]

مجله علمی دانشگاه علوم پزشکی کردستان, 2023
Background and Aim: Doxorubicin is an effective chemotherapeutic agent. However, use of this drug is limited due to its dose-dependent cardiotoxicity. Activation of apoptotic pathways in myocardial tissue plays an important role in doxorubicin- induced ...
Hossein Piri, Ehsan Aali, Samaneh Keshavarz Hedayati, Sanaz Keshavarz Shahbaz, Yazdan Naderi   +4 more
doaj  

Minocycline-based therapy for carbapenem-resistant Acinetobacter baumannii pneumonia: A multicenter retrospective study

International Journal of Infectious Diseases
Background: Minocycline is one of the few antibiotics that remain highly effective against carbapenem-resistant Acinetobacter baumannii (CRAB). However, the efficacy of minocycline for treating CRAB pneumonia has not been clearly demonstrated yet ...
Hyeri Seok, Si-Ho Kim, Hye Jin Shi, Won Suk Choi, Dae Won Park, Yu Mi Wi, Cheon-Hoo Jeon, Yoonseon Park, Shin Hee Hong, Kyungmin Huh   +9 more
doaj   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

A double-blind placebo-controlled trial of minocycline on translocator protein distribution volume in treatment-resistant major depressive disorder

Translational Psychiatry, 2021
Gliosis is implicated in the pathophysiology of many neuropsychiatric diseases, including treatment-resistant major depressive disorder (TRD). Translocator protein total distribution volume (TSPO VT), a brain marker mainly reflective of gliosis in ...
Sophia Attwells, Elaine Setiawan, Pablo M. Rusjan, Cynthia Xu, Stephen J. Kish, Neil Vasdev, Sylvain Houle, Apitharani Santhirakumar, Jeffrey H. Meyer   +8 more
doaj   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Minocycline Nanocrystals: A New Approach for Treating Acne with Reduced Systemic Side Effects

Pharmaceutics
Background/Objectives: Acne vulgaris is a chronic skin infection characterized by high sebum secretion, keratosis around hair follicles, inflammation, and imbalance in androgen levels. Acne vulgaris causes permanent scars or skin pigmentation in cases of
Suha M. Abudoleh, Juhaina M. Abu Ershaid, Dima Lafi, Nisreen A. Dahshan, Ahmad Talhouni, Amjad Abuirmeileh   +5 more
doaj   +1 more source

Minocycline for Controlling Neuropathic Pain: A Systematic Narrative Review of Studies in Humans

Journal of Pain Research, 2021
Dong Ah Shin,1 Tae Uk Kim,2 Min Cheol Chang3 1Department of Neurosurgery, Yonsei University, College of Medicine, Seoul, Republic of Korea; 2Department of Physical Medicine and Rehabilitation, College of Medicine, Dankook University, Cheonan, Republic of
Shin DA, Kim TU, Chang MC
doaj  

Diffuse skin hyperpigmentation associated with chronic minocycline use in a patient with prosthetic joint infection

IDCases, 2017
Cutaneous hyperpigmentation is a recognized adverse effect of chronic minocycline use occurring in up to 50% of patients. In this report we present a rare case of extensive skin hyperpigmentation involving both lower extremities in a patient receiving ...
Hadi Berbari, Elie F. Berbari, Irene G. Sia   +2 more
doaj   +1 more source

Minocycline intra-bacterial pharmacokinetic hysteresis as a basis for pharmacologic memory and a backbone for once-a-week pan-tuberculosis therapy

Frontiers in Pharmacology, 2022
Background: There is need for shorter duration regimens for the treatment of tuberculosis, that can treat patients regardless of multidrug resistance status (pan-tuberculosis).Methods: We combined minocycline with tedizolid, moxifloxacin, and rifampin ...
Devyani Deshpande, Shashikant Srivastava, Jotam Garaimunashe Pasipanodya, Tawanda Gumbo, Tawanda Gumbo   +4 more
doaj   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source