Results 141 to 150 of about 57,216 (335)

Hemocyanin-derived phenoloxidase activity: A contributing factor to hyperpigmentation in Nephrops norvegicus

open access: yes, 2013
The phenomenon of hyperpigmentation (melanosis) in shellfish has long been attributed to phenoloxidase enzymes. Over the last number of years, the oxygen carrier hemocyanin, has demonstrated several immune- and physiological functionalities, most notably,
Coates, Christopher J.   +2 more
core   +1 more source

Self-Delivering RNAi Compounds for Reduction of Hyperpigmentation

open access: yes
Melissa Maxwell, Katherine Holton, Richard J Looby, Michael Byrne, James Cardia Phio Pharmaceuticals, Marlborough, MA, USACorrespondence: Melissa Maxwell, Phio Pharmaceuticals, 11 Apex Dr., Ste.
Byrne M   +4 more
core  

Efficacy and Safety of Anal High‐Grade Squamous Intraepithelial Lesion Treatment Modalities: A Systematic Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino   +5 more
wiley   +1 more source

Age distribution and characteristics of choroidal nevi in 35 559 individuals: A nationwide study using optometry fundus photography

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To examine the age distribution and characteristics of choroidal nevi in a large nationwide sample. Methods We included all individuals who underwent fundus photography in a nationwide chain of optometry stores during a 5‐week period in 2023.
Carsten Faber   +3 more
wiley   +1 more source

Allgrove Syndrome with Absent Adrenal Gland in a Child: A Case Report

open access: yesIndian Pediatrics Case Reports
Background: Allgrove syndrome is an autosomal recessive disorder caused by mutation in AAAS gene and characterized by alacrimia, achalasia, and adrenal insufficiency. Subtle clinical features may be the only findings and need good workup.
Medha Mittal   +5 more
doaj   +1 more source

Novel Postzygotic Variants Associated With Hypomelanosis of Ito Expand the ACTB‐Related Neurocutaneous Disease Spectrum

open access: yesClinical Genetics, EarlyView.
We describe a previously unreported phenotype related to postzygotic ACTB variants with hypomelanosis of Ito, characterized by hypopigmentation associated or not with neurodevelopmental features, distinct from Becker presentations, bridging constitutional neurodevelopmental and somatic cutaneous phenotypes.
Estella Castillon   +9 more
wiley   +1 more source

Addison’s disease without hyperpigmentation in pediatrics: pointing towards specific causes

open access: yes, 2023
Introduction: Hyperpigmentation of skin and mucous membranes comprises a hallmark of the clinical diagnosis of Addison’s disease. However, there have been reports of patients with adrenal insufficiency from diverse causes who did not develop ...
Efthymiadou, A.   +3 more
core  

Contact Sensitization in Patients With Frontal Fibrosing Alopecia: Patch Test Results With an Extended Baseline Series in Consecutive Patients

open access: yesContact Dermatitis, EarlyView.
Sensitization to propolis, shellac and gallate mix is FFA‐associated, but its relevance is largely unknown. Sensitization to salicylates is frequent and associated with symptoms of intolerance to sun exposure or sunscreens. No significant improvement by allergen avoidance is identified.
María‐Antonia Pastor‐Nieto   +11 more
wiley   +1 more source

Tranexamic Acid for the Treatment of Hyperpigmentation and Telangiectatic Disorders Other Than Melasma: An Update

open access: yes
Tianyu Chen,1 Jing Xue,2 Qian Wang2 1School of Medicine, University of Electronic Science and Technology of China, Chengdu, People’s Republic of China; 2The Institute of Dermatology and Venereology, Sichuan Provincial People’s Hospital, School of ...
Wang Q, Xue J, Chen T
core  

Metformin: A Potential Drug to Treat Hyperpigmentation Disorders

open access: yes, 2014
Hyperpigmentation disorders are generally difficult to treat because of the limited availability of effective therapeutics with minimal side effects. In this issue, Lehraiki et al.
Park, Hee-Young, Belisle, Elisabeth S.
core   +1 more source

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