Results 91 to 100 of about 342,355 (309)

Malignant transformation in oral epithelial dysplasticlesions: An observational study

Journal of Health Sciences
Introduction: This research study is a comprehensive analysis of cases oral epithelial dysplasia (OED) to oral squamous cell carcinoma (OSCC) over the past decade, with a particular focus on eliciting the frequency of malignant transformation (MT) of ...
Anuhya Jayanthi, Sagar Krishna, Sunitha Carnelio, Vasudeva Guddattu, Spoorti Kulkarni   +4 more
doaj   +1 more source

Supplementation of grazing beef cows during gestation as a strategy to improve skeletal muscle development of the offspring

Animal, 2017
The appropriate supply of nutrients in pregnant cows has been associated with the optimal development of foetal tissues, performance of their progeny and their meat quality. The aim of this study was to evaluate supplementation effects of grazing cows in
D.C. Marquez, M.F. Paulino, L.N. Rennó, F.C. Villadiego, R.M. Ortega, D.S. Moreno, L.S. Martins, D.M. de Almeida, M.P. Gionbelli, M.R. Manso, L.P. Melo, F.H. Moura, M.S. Duarte   +12 more
doaj   +1 more source

Pharmacological treatment of benign prostatic hyperplasia

, 2017
Lower urinary tract symptoms (LUTS) is the major clinical manifestation of benign prostatic hyperplasia (BPH) which is one of the most common disorders that affects the aging male population.
Economou, Spyros
core  

SSR4 sustains Tertiary Lymphoid Structures by Regulation Quality Control of N‐linked Glycosylation During B‐cell Differentiation Into Plasmacyte in Colorectal Cancer

Advanced Science, EarlyView.
SSR4, a TRAP component induced in B cells, governs BAFFR N‐glycosylation via DDOST to sustain NF‐κB signaling, B‐cell differentiation, and TLS maturation. Its loss impairs anti‐tumor immunity, while overexpression improves antibody glycosylation and ADCC, revealing a critical regulator for cancer immunotherapy.
Wei Zhao, Youcai Zhao, Haiyang Li, Bowen Yang, Siyan Lu, Xueting Fu, Caixia Zhang, Yirong Chen, Xiaofeng Bian, Xinghua Ma, Xiaobing Yang, Bin Wang, Yuan Fang, Lulu Yang, Yelin Zhao, Shuli Zhao   +15 more
wiley   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

Verrucous Hyperplasia : Case report and differential diagnosis

Sultan Qaboos University Medical Journal, 2017
Verrucous hyperplasia (VH) is a rare exophytic oral mucosal lesion which can transform into verrucous carcinoma (VC), its malignant but clinically similar counterpart.
Sonal Grover, Mihir Jha, Bhushan Sharma, Shekhar Kapoor, Kumud Mittal, Nithin K. Parakkat, Anil B. Shivappa, Ravleen Kaur   +7 more
doaj   +1 more source

Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc

, 2008
Context: Mitochondrial cytochrome P450scc converts cholesterol to pregnenolone in all steroidogenic tissues. Although progesterone production from the fetally-derived placenta is necessary to maintain pregnancy to term, four patients with mutations in ...
Huang, NW, Achermann, JC, Lin, L, Kim, CJ, Miller, WL, Quigley, CA, AvRuskin, TW   +6 more
core  

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

Advanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang, Yingying Wang, Lujie Yu, Chunmei Jiang, Haoyu Liu, Yaohua Chen, Shutong Wu, Qin Liu, Lingling Wei, Xiaochun Zheng, Huifang Hao, Mengting Gao, Weiwei Kang, Rong Dai, Ziliang Zheng, Ruiping Zhang   +15 more
wiley   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

BJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek, M. Almquist, A. O. Bergenfelz, T. J. Musholt, E. Nordenström, on behalf of the EUROCRINE® Council, M. Almquist, M. Barczynski, L. Brunaud, T. Clerici, M. H. Hansen, M. Iacobone, Ö. Makay, F. F. Palazzo, N. Muñoz‐Pérez, M. Raffaelli, P. Riss, S. van Slycke, M. R. Vriens   +18 more
wiley   +1 more source

Hypoplastic Left Heart Syndrome: A New Paradigm for an Old Disease?

Journal of Cardiovascular Development and Disease, 2019
Hypoplastic left heart syndrome occurs in up to 3% of all infants born with congenital heart disease and is a leading cause of death in this population. Although there is strong evidence for a genetic component, a specific genetic cause is only known in ...
Paul Grossfeld, Shuyi Nie, Lizhu Lin, Lu Wang, Robert H. Anderson   +4 more
doaj   +1 more source