Results 121 to 130 of about 342,355 (309)

Mechanism of Ciclosporin-induced gingival hyperplasia An in vitro study of the effect of ciclosporin on human gingival fibroblasts and oral keratinocytes

, 2011
PhDObjectives: Ciclosporin (CsA) is a potent and effective immuno-suppressive drug, but its use is associated with the development of gingival hyperplasia in up to 70% of patients.
Hanino, Mohammad
core  

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Travis, W., Beuschlein, Felix, Karl, M., Chrousos, G. P., Abdelhamid, S., Allolio, B., Jaursch-Hancke, C., Reincke, Martin   +7 more
core  

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Pathological Characterization and Risk Factors of Splenic Nodular Lesions in Dogs (Canis lupus familiaris)

Animals
In dogs, the spleen is a secondary lymphoid organ that can be affected by both neoplastic and non-neoplastic nodules. In general, few studies relate histopathological diagnosis to tumor size and the number of nodules in spleen biopsies.
Gloria Corvera, Raúl Alegría-Morán, Federico Francisco Cifuentes, Cristian Gabriel Torres   +3 more
doaj   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Telomeres and telomerase in endometrial cancer and hyperplasia

Introduction The study aimed to measure telomeres length (TL) and telomerase expression in normal endometrium and endometrial hyperplasia and cancer. Material and methods Total RNA and DNA were isolated from endometrium samples of 117 patients.
Anna Pańczyszyn, Karolina Włodarczyk, Ewa Boniewska-Bernacka, Iwona Wertel, Anna Goc   +4 more
core   +1 more source

Genetic prediction of blood cell reactivity and its potential causal influence on bone continuity and density disorders

Animal Models and Experimental Medicine, EarlyView.
We applied Mendelian randomization to explore causal links between blood cell traits and skeletal disorders. Using genetic instruments from large‐scale summary statistics, we assessed effects on bone continuity, density, and structural integrity. Sensitivity and reverse analyses confirmed robust associations, highlighting potential shared biological ...
Zhiqin Deng, Zhe Zhao, Wenting Jiang, Xiaoqiang Chen, Jianquan Liu, Xu Tao, Zhengyang Lin, Zhenhan Deng, Wencui Li   +8 more
wiley   +1 more source

Bilateral Condylar Hyperplasia: Importance of Its Diagnosis in the Treatment and Long-Term Stability of Skeletal Class III Correction

Diagnostics
Background: Condylar hyperplasia (CH) leads to mandibular overgrowth with anatomical, aesthetic, and functional consequences, particularly affecting facial harmony. It is characterized by severe mandibular prognathism (MP) in bilateral cases.
Diego Fernando López, Martín Fernando Orozco, Sofia Ochoa Gómez, Santiago Herrera Guardiola, Luis Eduardo Almeida   +4 more
doaj   +1 more source

Papilloma and sebaceous gland hyperplasia of the lacrimal caruncle: a case report

, 2018
Maria Miura-Karasawa,1 Hiroshi Toshida,1 Toshihiko Ohta,1 Akira Murakami2 1Department of Ophthalmology, Juntendo University Shizuoka Hospital, Izunokuni, Shizuoka, Japan; 2Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan ...
Ohta T, Miura-Karasawa M, Murakami A, Toshida H   +3 more
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Condylar Hyperplasia

, 2014
Condylar hyperplasia is a rare pathology of the growth of the mandibular condylar cartilage leading to facial deformation. A bone scan demonstrates the active or inactive character of the condylar hyperplasia and helps guide therapeutic choices.
Marion Billet, Bernard Cadre
core   +1 more source