Results 181 to 190 of about 61,022 (308)

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Transcranial direct current stimulation: challenges, opportunities and impact on psychiatry and neurorehabilitation

Frontiers in Psychiatry, 2013
Andre R Brunoni, Felipe eFregni, Alberto ePriori, Roberta eFerrucci, Paulo Sérgio Boggio   +4 more
doaj   +1 more source

Isoflurane causes muscle contraction in <i>Drosophila melanogaster</i> despite inducing hyperpolarized state. [PDF]

MicroPubl Biol
Griffith J, Kim J, Cooper R.
europepmc   +1 more source

Noise‐induced reduction and early recovery of superior paraolivary nucleus sound‐offset responses

The Journal of Physiology, EarlyView.
Abstract figure legend Acoustic over‐exposure transiently disrupts auditory temporal processing in mouse superior paraolivary nucleus neurons. In control conditions, neurons exhibit robust sound‐offset (OFF) responses, which are abolished immediately following noise trauma, indicating impaired temporal encoding.
Mihai Stancu, Ezhilarasan Rajaram, Joseph A. Kroeger, Benedikt Grothe, Conny Kopp‐Scheinpflug   +4 more
wiley   +1 more source

Potassium channel-targeted therapy in reducing vascular complications in diabetes mellitus: novel insights. [PDF]

Front Pharmacol
Rajkovic J, Ribic A, Rekovic L, Gostimirovic M, Bukarica A, Terzic D, Gojkovic-Bukarica L.   +6 more
europepmc   +1 more source

Solvents effects in SABRE-based nuclear spin hyperpolarization

Introduction One of the most promising signal enhancement techniques with respect to future biomedical applications is parahydrogen-based nuclear spin hyperpolarization.[1] In particular, the method Signal Amplification by Reversible Exchange (SABRE ...
Bullinger, F., Bernarding, J., Plaumann, M., Pravdivtsev, A., Houben, T., Myers, J., Körber, R., Kempf, N. ; https://orcid.org/, Mysegaes, F., Assaf, C., Buckenmaier, K. ; https://orcid.org/   +10 more
core  

Stac2 genetic deletion alters mouse chromaffin cells’ CaV channel composition, increases membrane excitability and reduces vesicle exocytosis

The Journal of Physiology, EarlyView.
Abstract figure legend Stac2 adaptor protein is expressed in neurons and endocrine cells. Using a global Stac2 knockout mouse model here we investigated the role of endogenous Stac2 in adrenal gland mouse chromaffin cell (MCC) excitability and catecholamine vesicle exocytosis.
Stefanie M. Geisler, Noelia Jacobo‐Piqueras, Tamara Theiner, Ryoichi S. Taguchi, Laura E. Häfele, Marta Campiglio, Petronel Tuluc   +6 more
wiley   +1 more source

Benchtop NMR signal enhancement of metabolites in urine extract using SABRE. [PDF]

Chem Commun (Camb)
Fleischer S, Yang J, Ausmees K, Reile I, MacKinnon N, Korvink JG, Lehmkuhl S.   +6 more
europepmc   +1 more source

Intercalated disk structure, tissue heterogeneity and ion channel distribution modulate conduction and local calcium influx

The Journal of Physiology, EarlyView.
Abstract figure legend A, three‐dimensional representation of cardiac intercalated disk, reduced to a 100‐partition, computationally efficient network representation. B, ion dynamics within intercalated disk extracellular cleft space. C, rapid pacing leads to localized conduction block in tissue with regions of perturbed intercalated disk (ID ...
Nicolae Moise, Heather L. Struckman, James W. Smyth, Gregory S. Hoeker, Steven Poelzing, Rengasayee Veeraraghavan, Seth H. Weinberg   +6 more
wiley   +1 more source

IrTMes - a stable SABRE catalyst for the hyperpolarization of [1-¹³C]-pyruvate.

Analyst
Wacker J, Korvink JG, Lehmkuhl S.
europepmc   +1 more source