Results 181 to 190 of about 51,213 (265)

Atlas of Brain Glucose Metabolism Using Deuterium Metabolic Imaging at 3 T

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1834-1845, October 2026.
ABSTRACT Purpose Deuterium metabolic imaging (DMI) offers noninvasive magnetic resonance imaging (MRI)–based assessment of metabolism in vivo, making it a relevant paraclinical tool for diseases with neurological metabolic alterations. This study aimed to establish a normative reference atlas of brain glucose metabolism accounting for age and sex ...
Kamilla K. Trosborg, Nichlas V. Christensen, Malene Aastrup, Nikolaj Bøgh, Janne K. Mortensen, Hanne Gottrup, Per Borghammer, Mattias H. Kristensen, Esben S. S. Hansen, Sofie H. Christensen, Jack J. Miller, Rolf F. Schulte, Michael Vaeggemose, Lotte B. Bertelsen, Christoffer Laustsen   +14 more
wiley   +1 more source

Biocompatible SABRE Hyperpolarization of [1-¹³C]Ketoleucine for Cellular Metabolic Flux Sensing. [PDF]

Chemistry
TomHon P, Gyesi J, Abdurraheem A, McBride S, Samoilenko A, Oladun C, Curran E, Pike M, Welch SD, Scofield S, Goodson BM, Sadagurski M, Theis T, Chekmenev EY.   +13 more
europepmc   +1 more source

A Modified Balanced Steady State Free Precession Sequence for Overhauser Magnetic Resonance Imaging

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1655-1665, October 2026.
ABSTRACT Purpose Low‐ and ultralow‐field magnetic resonance imaging (ULF MRI) have inherently low signal‐to‐noise ratio (SNR) by design. Overhauser dynamic nuclear polarization (ODNP) stands out as an effective solution for continuous signal enhancement.
Kai Buckenmaier, Friedemann Bullinger, Georgiy Alekseevich Solomakha, Marcel Schneider, Jörn Engelmann, Philipp Pohlmann, Pavel Povolni, Laura Kuebler, André Ferreira Martins, Klaus Scheffler   +9 more
wiley   +1 more source

Open-Source Multinuclear Low-Field Preclinical MRI Scanner. [PDF]

NMR Biomed
Rodriguez GG, Korchak S, von Petersdorff-Campen C, Sucre O, Felger J, Mei R, Glöggler S.   +6 more
europepmc   +1 more source

Parvalbumin interneurons in Alzheimer's disease: Physiological insights and pathophysiological mechanisms

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Physiological and Pathological Alterations in PV+ Neurons: Under physiological conditions, PV+ interneurons exhibit fast‐spiking properties and generate gamma oscillations at the cost of high energy consumption. In AD, PV+ neurons display abnormalities in ion channels, dendrites, neurotransmission, energy metabolism, and neural oscillations, ultimately
Mengyan Wu, Xingdong Zeng, Yongle Cai, Haonan Chen, Qianying Li, Hao Yang   +5 more
wiley   +1 more source

Noradrenergic inhibition of definitive POMC neurons through direct and indirect mechanisms. [PDF]

J Neuroendocrinol
Lavoie O, Turmel A, Khouma A, Minbashi Moeini M, Liu C, Michael NJ, Caron A.   +6 more
europepmc   +1 more source

Unveiling the Functional Role of KIF21B in Microglia Inflammatory Response

Glia, Volume 74, Issue 9, September 2026.
Microglia express KIF21B in both sexes. KIF21B binds to microglia cytoskeleton; inflammation alters such interaction promoting a phagocytic state in females. In male microglia KIF21B modulates migration. ABSTRACT Microglia are brain immune cells that maintain homeostasis and respond to injury, changing cell morphology to drive inflammation, migration ...
Danny Ganchala, Alvaro Bautista‐Abad, Daniel Pinto‐Benito, Julia Simon‐Areces, Daniela Grassi, Francesco Paolo Ulloa Severino, Maria‐Angeles Arevalo   +6 more
wiley   +1 more source

Mitochondrial acid-sensing ion channel 1a deficiency induces mitochondrial dysfunction in pulmonary arterial smooth muscle cells. [PDF]

Am J Physiol Lung Cell Mol Physiol
Tuineau MN, Herbert LM, Medina HE, Naik JS, Resta TC, Jernigan NL.   +5 more
europepmc   +1 more source

Dorso‐Ventral and Night‐Day Regulation of Extracellular K+ Dynamics in Mouse Hippocampal Astrocytes

Glia, Volume 74, Issue 9, September 2026.
Hippocampal astrocytic K+ buffering varies by region and time. Ventral astrocytes show faster K+ accumulation due to reduced Kir4.1 function. Such regional divergence is modulated by circadian shifts in Kir4.1 and gap junction coupling. ABSTRACT Astrocytes regulate extracellular potassium (K+) through multiple mechanisms operating across distinct ...
Nariman Kiani, Kabeer Abubakar, Tin Luka Petanjek, Monique Esclapez, Anton Ivanov, Christophe Bernard   +5 more
wiley   +1 more source

Optical Mapping of Pacing-Elicited Slow Waves in the Swine Stomach: Role of Virtual Electrodes. [PDF]

Neurogastroenterol Motil
Zhang H, Patton HN, Nagahawatte ND, Guragain B, Cheng LK, Walcott GP, Rogers JM.   +6 more
europepmc   +1 more source