Results 161 to 170 of about 51,213 (265)

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George   +5 more
wiley   +1 more source

Combining photo-CIDNP and long-lived spin states enables high-contrast detection of weak protein-ligand interactions.

open access: yesPhys Chem Chem Phys
Bütikofer M   +6 more
europepmc   +1 more source

Over four minutes of pyruvate T<sub>1</sub> using chemically and physically induced deceleration of relaxation. [PDF]

open access: yesNat Commun
Peters JP   +8 more
europepmc   +1 more source

Maturation of spinal motor control through developmental changes in ion currents

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Ion channels of spinal neurons have been shown to change during development in a wide range of species. These changes occur at specific stages of development. An important developmental process is the maturation of motor control by which the body acquires new movements or refines movements already present.
Stephanie F. Gaudreau, Tuan V. Bui
wiley   +1 more source

Modelling the memory of unmyelinated axons: Integration of a data‐driven approach with physiological memory concept

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Simplified and resource‐efficient computational model for predicting activity‐dependent conduction velocity changes in individual spikes within spike trains in unmyelinated axons. Fibre memory: The conduction speed of each action potential is modulated non‐linearly by the axon's prior activity.
Anna Maxion   +3 more
wiley   +1 more source

Intrinsic pH chemosensitivity of acutely dissociated medullary serotonergic and retrotrapezoid neurones

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Central respiratory chemoreceptors (CRCs) are critical for maintaining normal systemic levels of pH and PCO2. A CRC must respond to pH via intrinsic mechanisms. Here we quantified intrinsic chemosensitivity of medullary 5‐HT neurones and retrotrapezoid nucleus (RTN) neurones using acute dissociation.
Yuanming Wu   +2 more
wiley   +1 more source

Sperm plasma membrane potential as a marker for fertilization success for non-normozoospermic patients undergoing assisted reproduction technologies. [PDF]

open access: yesJ Assist Reprod Genet
Carrasquel-Martínez G   +7 more
europepmc   +1 more source

Electrostatic tuning of NaV channel activation by the domain II S3–S4 extracellular loop

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Voltage‐gated sodium (NaV) channels are critical for electrical signalling, yet the molecular determinants that tune isoform‐specific activation remain incompletely understood. Here, we show that charged amino acids in the extracellular DII S3–S4 loop of NaV1.7 play a key role in setting voltage‐dependent activation.
Ashvriya Thapa   +5 more
wiley   +1 more source

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