Results 151 to 160 of about 88,078 (299)

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

open access: yesThe FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi   +12 more
wiley   +1 more source

Effect of sodium–glucose cotransporter 2 inhibitors on heart failure readmission in older patients with diabetes: A Japanese claims‐based cohort study

open access: yesJournal of Diabetes Investigation, EarlyView.
SGLT2 inhibitor use at discharge was associated with a reduced risk of heart failure readmission in elderly patients with diabetes, with no significant differences among individual agents. ABSTRACT Aims To evaluate the effect of sodium–glucose cotransporter 2 inhibitor (SGLT2i) administration at hospital discharge on heart failure (HF) readmission ...
Kazuya Hiura   +3 more
wiley   +1 more source

Optimization of photobiomodulation therapy for spinal cord injury: A review

open access: yesPhotochemistry and Photobiology, EarlyView.
Photobiomodulation (PBM) therapy in the red and near‐infrared range can significantly modulate the secondary injury response and promote the reparative and regenerative potential of neural tissue after spinal cord injury (SCI). At present, due to the nature of delivery methods, the most effective dose and irradiance at the injury site to optimize ...
Isabella K. M. Drew   +3 more
wiley   +1 more source

From cognitive coherence to political polarization: A data‐driven agent‐based model of belief change

open access: yesPolitical Psychology, EarlyView.
Abstract Political polarization represents a rising issue in many countries, making it more and more important to understand its relation to cognitive‐motivational and social influence mechanisms. Yet, the link between micro‐level mechanisms and macro‐level phenomena remains unclear.
Marlene C. L. Batzke   +4 more
wiley   +1 more source

Partisans' evaluations of unconstitutional legislative activity

open access: yesPolicy Studies Journal, EarlyView.
Abstract In this research note, we examine whether public evaluations of a policy depend on the constitutionality of the process by which that policy was passed. We observe whether people's views depend on accusations that a policy was passed in violation of a state constitution's single subject rule, and whether the effect of that accusation depends ...
Kevin K. Banda   +2 more
wiley   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

open access: yesExperimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Ultra-low field <sup>13</sup>C MRI of hyperpolarized pyruvate. [PDF]

open access: yesCommun Chem
Boele T   +12 more
europepmc   +1 more source

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