Results 281 to 290 of about 129,353 (325)
A conserved bioelectrical signature defines subventricular zone-derived human fetal neural stem cells and tracks their differentiation state. [PDF]
Front Cell Dev BiolDe Zio R +9 more
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Phase-specific premotor inhibition modulates leech rhythmic motor output. [PDF]
ElifeRadice M +3 more
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Dual block evidence of the effects of topiramate, a sulfamate-substituted monosaccharide, on voltage-gated sodium current and hyperpolarization-activated cation current. [PDF]
BMC Pharmacol ToxicolTzeng RC, Lai MC, Wu SN, Huang CW.
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Transcriptional and electrical identity in endothelial cells is orchestrated by intercellular coupling. [PDF]
Front PhysiolBurboa PC +4 more
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Biochemical Pharmacology, 1997
There is now overwhelming evidence for factors, other than nitric oxide (NO), that mediate endothelium-dependent vasodilation by hyperpolarizing the underlying smooth muscle via activation of Ca2+-activated K+ channels. Although the identity of endothelium-derived hyperpolarizing factor (EDHF) remains to be established, cytochrome P450 (CYP)-dependent ...
J, Quilley, D, Fulton, J C, McGiff
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There is now overwhelming evidence for factors, other than nitric oxide (NO), that mediate endothelium-dependent vasodilation by hyperpolarizing the underlying smooth muscle via activation of Ca2+-activated K+ channels. Although the identity of endothelium-derived hyperpolarizing factor (EDHF) remains to be established, cytochrome P450 (CYP)-dependent ...
J, Quilley, D, Fulton, J C, McGiff
openaire +2 more sources
SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization.
Progress in nuclear magnetic resonance spectroscopy, 2019In this review, we present the physical principles of the SABRE (Signal Amplification By Reversible Exchange) method. SABRE is a promising hyperpolarization technique that enhances NMR signals by transferring spin order from parahydrogen (an isomer of ...
D. Barskiy +3 more
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Current Pharmaceutical Biotechnology, 2010
Hyperpolarized (HP) (13)C labeled compounds can be used as MR contrast agents to investigate metabolic pathways in vivo in almost real time. To date, a high proportion of reported studies have utilized HP 1-(13)C pyruvate to investigate intracellular metabolism in tumors and other tissues. The long T(1) relaxation time of the carboxylate carbon enables
Ian J, Rowland +3 more
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Hyperpolarized (HP) (13)C labeled compounds can be used as MR contrast agents to investigate metabolic pathways in vivo in almost real time. To date, a high proportion of reported studies have utilized HP 1-(13)C pyruvate to investigate intracellular metabolism in tumors and other tissues. The long T(1) relaxation time of the carboxylate carbon enables
Ian J, Rowland +3 more
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ENDOTHELIUM‐DERIVED HYPERPOLARIZING FACTOR
Clinical and Experimental Pharmacology and Physiology, 1996SUMMARY1. Not all endothelium‐dependent relaxation can be full explained by the release of either nitric oxide (NO) and/or prostacyclin. Another unidentified substance(s) that hyperpolarizes the underlying vascular smooth muscle cells (endothelium‐derived hyperpolarizing factor; EDHF) contributes to endothelium‐dependent relaxations.2. In blood vessels
Vanhoutte, PMGR, Félétou, M
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Endothelium-Derived Hyperpolarizing Factor
Journal of Vascular Research, 1990Although nitric oxide appears to be the major endothelium-derived relaxing factor (EDRF), it cannot explain all endothelium-dependent responses of isolated arteries. Thus, acetylcholine causes an endothelium-dependent, transient hyperpolarization, which is due to the release from the endothelial cells of a diffusible substance (endothelium-derived ...
Komori, K, Vanhoutte, PMGR
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