Results 261 to 270 of about 88,078 (299)
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Endothelium-dependent hyperpolarizations: the history

Pharmacological Research, 2004
Endothelial cells control the tone and the growth of the underlying vascular smooth muscle by releasing Nitric Oxide (NO). This introduction summarizes the early experiments which first suggested and then demonstrated the existence of an alternative pathway, endothelium-dependent hyperpolarization.
openaire   +4 more sources

Prostacyclin and endothelium-dependent hyperpolarization

Pharmacological Research, 2004
Prostacyclin released from the endothelium is capable of relaxing vascular smooth muscle. Here, we review the mechanisms underpinning this relaxation, with a focus on the role of smooth muscle hyperpolarization. The contribution of endothelium-derived prostacyclin to overall blood pressure is discussed.
Helena C, Parkington   +2 more
openaire   +2 more sources

Hyperpolarization/Depolarization on Human Spermatozoa

Archives of Andrology, 1991
The accumulation of the lipophilic cation radiolabeled triphenylmethylphosphonium (TPMP+) was utilized to determine the resting membrane potential across the plasma membrane (psi) of human sperm. Washed sperm were suspended and incubated in low-K+ and high-K+ medium and allowed to take up the cation to a steady state (20 min at 37 degrees C).
L, Calzada, E L, Salazar, H, Macias
openaire   +2 more sources

Applications of Hyperpolarized Agents in Solutions

2011
This chapter provides an overview of pulse sequences adapted to hyperpolarized MR imaging. Applications of hyperpolarized agents in aqueous solution are reviewed. Vascular (e.g., angiography, perfusion, and catheter tracking) as well as metabolic (e.g., oncology, cardiology, neurology, and pH mapping) applications are covered.
Jan Henrik, Ardenkjaer-Larsen   +3 more
openaire   +2 more sources

Dynamic Nuclear Hyperpolarization in Liquids

2011
Nuclear magnetic resonance (NMR) spectroscopy is a broadly used analytical method with major applications in chemistry, biochemistry and medicine. Key applications include structural analysis of small molecules, metabolites, larger biomolecules such as proteins, RNA and DNA, and applications in material science.
openaire   +2 more sources

Hyperpolarization

2010
Michael H. Bloch   +94 more
openaire   +1 more source

Structures of the Human HCN1 Hyperpolarization-Activated Channel

Cell, 2017
Chia-Hsueh Lee, Roderick Mackinnon
exaly  

Quantitative Trace Analysis of Complex Mixtures Using SABRE Hyperpolarization

Angewandte Chemie - International Edition, 2015
Martin C Feiters   +2 more
exaly  

Voltage Sensor Movements during Hyperpolarization in the HCN Channel

Cell, 2019
Chia-Hsueh Lee, Roderick Mackinnon
exaly  

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